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Original Research

The safety and tolerability evaluation of DepoFoam bupivacaine (bupivacaine extended-release liposome injection) administered by incision wound infiltration in rabbits and dogs

, PhD, , , , , , , & show all
Pages 1327-1341 | Published online: 26 Aug 2011

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Read on this site (4)

Mark Lambrechts, Michael J O’Brien, Felix H Savoie & Zongbing You. (2013) Liposomal extended-release bupivacaine for postsurgical analgesia. Patient Preference and Adherence 7, pages 885-890.
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Brian M Ilfeld. (2013) Liposome bupivacaine in peripheral nerve blocks and epidural injections to manage postoperative pain. Expert Opinion on Pharmacotherapy 14:17, pages 2421-2431.
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Praveen Chahar & Kenneth C Cummings$suffix/text()$suffix/text(). (2012) Liposomal bupivacaine: a review of a new bupivacaine formulation. Journal of Pain Research 5, pages 257-264.
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Articles from other publishers (36)

Alexander P. Rahn, George E. Moore & Marije Risselada. (2023) Postoperative injectable opioid use and incidence of surgical site complications after use of liposomal bupivacaine in canine gastrointestinal foreign body surgery. Veterinary Surgery.
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Bill Kellner & Lauren Duffee. (2023) Liposomal Bupivacaine in Dentistry and Oral and Maxillofacial Surgery. A Review of Human and Veterinary Literature.. Journal of Veterinary Dentistry, pages 089875642311570.
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Berit Otremba, Hanns-Christian Dinges, Ann-Kristin Schubert, Wolfgang Zink, Thorsten Steinfeldt, Hinnerk Wulf & Thomas Wiesmann. (2022) Liposomales Bupivacain – kein Durchbruch in der postoperativen SchmerztherapieLiposomal bupivacaine—No breakthrough in postoperative pain management. Die Anaesthesiologie 71:7, pages 556-564.
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Gredson Keiff Souza, André Gallo, Luiza Hauser Novicki, Heitor Rodrigues Neto, Eneida de Paula, Anita Jocelyne Marsaioli & Luis Fernando Cabeça. (2022) Inclusion Complex between Local Anesthetic/2-hydroxypropyl-β-cyclodextrin in Stealth Liposome. Molecules 27:13, pages 4170.
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Hüseyin Oğuz Yılmaz & Alparslan Turan. 2022. Treatments, Mechanisms, and Adverse Reactions of Anesthetics and Analgesics. Treatments, Mechanisms, and Adverse Reactions of Anesthetics and Analgesics 291 307 .
Fernando Freitas de Lima, Bianca Brandão da Silva, Juliana Damasceno Oliveira, Ludmilla David de Moura, Gustavo Henrique Rodrigues da Silva, Priscila Cordeiro Lima Fernandes, Roosevelt Isaias Carvalho Souza, Ariany Carvalho dos Santos & Eneida de Paula. (2021) Prolonged anesthesia and decreased toxicity of enantiomeric-excess bupivacaine loaded in ionic gradient liposomes. International Journal of Pharmaceutics 606, pages 120944.
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Brittany Knight, Joseph Walker & Lakshmi S. Nair. (2021) Perineural Local Anesthetic Treatments for Osteoarthritic Pain. Regenerative Engineering and Translational Medicine 7:3, pages 262-282.
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Christopher F. Tirotta, Richard G. Lagueruela, Daria Salyakina, Apeksha Gupta, Frank Alonso, Jason Inoa, Jessica Hughes, Jonathan Pappas & Redmond Burke. (2021) Liposomal Bupivacaine Infiltration After Median Sternotomy in Pediatric Cardiac Surgery. Journal of Cardiothoracic and Vascular Anesthesia 35:6, pages 1715-1721.
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Natasha C. Brigham, Ru-Rong Ji & Matthew L. Becker. (2021) Degradable polymeric vehicles for postoperative pain management. Nature Communications 12:1.
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W. Zink, T. Steinfeldt & T. Wiesmann. (2020) Bestandsaufnahme der Lokalanästhetika 2020Stocktaking of local anesthetics 2020. Der Anaesthesist 69:5, pages 301-313.
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Ian Duensing, Christopher L Peters, Priscila Monteiro, Mike B Anderson & Christopher E Pelt. (2020) Higher incidence of manipulation under anesthesia following TKA associated with the periarticular infiltration of a liposomal bupivacaine cocktail compared to a modified Ranawat cocktail. Journal of Orthopaedic Surgery 28:1, pages 230949902091081.
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Furqan A. Maulvi, Lakshmi V. Pillai, Kajal P. Patel, Ankita R. Desai, Manish R. Shukla, Ditixa T. Desai, Hetal P. Patel, Ketan M. Ranch, Shailesh A. Shah & Dinesh O. Shah. (2020) Lidocaine tripotassium phosphate complex laden microemulsion for prolonged local anaesthesia: In vitro and in vivo studies. Colloids and Surfaces B: Biointerfaces 185, pages 110632.
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Michele Barletta & Rachel Reed. (2019) Local Anesthetics. Veterinary Clinics of North America: Small Animal Practice 49:6, pages 1109-1125.
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Steve J.R. Coppens, Zoriana Zawodny, Geertrui Dewinter, Arne Neyrinck, Angela Lucia Balocco & Steffen Rex. (2019) In search of the Holy Grail: Poisons and extended release local anesthetics. Best Practice & Research Clinical Anaesthesiology 33:1, pages 3-21.
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Santhanam Suresh, David M. Polaner & Charles J. Coté. 2019. A Practice of Anesthesia for Infants and Children. A Practice of Anesthesia for Infants and Children 941 987.e9 .
Bryan D. Springer, J. Bohannon Mason & Susan M. Odum. (2018) Systemic Safety of Liposomal Bupivacaine in Simultaneous Bilateral Total Knee Arthroplasty. The Journal of Arthroplasty 33:1, pages 97-101.
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Ana Filipa Cruz, Nuno A. Fonseca, Ana C. Gregório, Vera Moura, Sérgio Simões & João Nuno Moreira. 2018. Particles and Nanoparticles in Pharmaceutical Products. Particles and Nanoparticles in Pharmaceutical Products 171 211 .
You Jin Jang, Jin Ho Lee, Tae Beom Seo & Se Heang Oh. (2017) Lidocaine/multivalent ion complex as a potential strategy for prolonged local anesthesia. European Journal of Pharmaceutics and Biopharmaceutics 115, pages 113-121.
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B. Duncan X. Lascelles, Lesley C. Rausch-Derra, Jessica A. Wofford & Margie Huebner. (2016) Pilot, randomized, placebo-controlled clinical field study to evaluate the effectiveness of bupivacaine liposome injectable suspension for the provision of post-surgical analgesia in dogs undergoing stifle surgery. BMC Veterinary Research 12:1.
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Eleftheria Kalogera, Jamie N. Bakkum-Gamez, Amy L. Weaver, James P. Moriarty, Bijan J. Borah, Carrie L. Langstraat, Christopher J. Jankowski, Jenna K. Lovely, William A. Cliby & Sean C. Dowdy. (2016) Abdominal Incision Injection of Liposomal Bupivacaine and Opioid Use After Laparotomy for Gynecologic Malignancies. Obstetrics & Gynecology 128:5, pages 1009-1017.
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B. Duncan X. Lascelles & Kristin Kirkby Shaw. (2016) An extended release local anaesthetic: potential for future use in veterinary surgical patients?. Veterinary Medicine and Science 2:4, pages 229-238.
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Luiz Eduardo Nunes Ferreira, Bruno Vilela Muniz, Cleiton Pita dos Santos, Maria Cristina Volpato, Eneida de Paula & Francisco Carlos Groppo. (2016) Comparison of liposomal and 2-hydroxypropyl-β-cyclodextrin–lidocaine on cell viability and inflammatory response in human keratinocytes and gingival fibroblasts. Journal of Pharmacy and Pharmacology 68:6, pages 791-802.
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Francesca Maestrelli, Marco Bragagni & Paola Mura. (2016) Advanced formulations for improving therapies with anti-inflammatory or anaesthetic drugs: A review. Journal of Drug Delivery Science and Technology 32, pages 192-205.
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Karina Gritsenko, Diego Fernandez Garcia-Roves, Boleslav Kosharskyy & Naum Shaparin. (2015) Postoperative Blocks That Afford Long-Lasting Pain Relief. Topics in Pain Management 31:3, pages 1-8.
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Hrishikesh C. Modi & Nicholas Lam. 2015. Decision-Making in Orthopedic and Regional Anesthesiology. Decision-Making in Orthopedic and Regional Anesthesiology 22 27 .
. 2015. Decision-Making in Orthopedic and Regional Anesthesiology. Decision-Making in Orthopedic and Regional Anesthesiology 1 46 .
Christopher AJ Webb & Edward R Mariano. (2015) Best multimodal analgesic protocol for total knee arthroplasty. Pain Management 5:3, pages 185-196.
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Taemin Kim, Dong Rim Seol, Suk-Chan Hahm, Cheolwoong Ko, Eun-Hye Kim, Keyoungjin Chun, Junesun Kim & Tae-Hong Lim. (2015) Analgesic Effect of Intra-Articular Injection of Temperature-Responsive Hydrogel Containing Bupivacaine on Osteoarthritic Pain in Rats. BioMed Research International 2015, pages 1-9.
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Christopher L. Norkus. 2014. Pain Management for Veterinary Technicians and Nurses. Pain Management for Veterinary Technicians and Nurses 125 146 .
Bret D. Ulery, Ho‐Man Kan, Bryce A. Williams, Balaji Narasimhan, Kevin W.‐H. Lo, Lakshmi S. Nair & Cato T. Laurencin. (2013) Facile Fabrication of Polyanhydride/Anesthetic Nanoparticles with Tunable Release Kinetics. Advanced Healthcare Materials 3:6, pages 843-847.
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J. Brian McAlvin, Robert F. Padera, Sahadev A. Shankarappa, Gally Reznor, Albert H. Kwon, Homer H. Chiang, Jason Yang & Daniel S. Kohane. (2014) Multivesicular liposomal bupivacaine at the sciatic nerve. Biomaterials 35:15, pages 4557-4564.
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Yi Cai Isaac Tong, Alan David Kaye & Richard D. Urman. (2014) Liposomal bupivacaine and clinical outcomes. Best Practice & Research Clinical Anaesthesiology 28:1, pages 15-27.
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J. Brian McAlvin & Daniel S. Kohane. 2014. Focal Controlled Drug Delivery. Focal Controlled Drug Delivery 653 677 .
Cheryl B. Greenacre. 2013. Pain Management in Veterinary Practice. Pain Management in Veterinary Practice 399 406 .
Dongrim Seol, Michael J. Magnetta, Prem S. Ramakrishnan, Gail L. Kurriger, Hyeonghun Choe, Keewoong Jang, James A. Martin & Tae‐Hong Lim. (2013) Biocompatibility and preclinical feasibility tests of a temperature‐sensitive hydrogel for the purpose of surgical wound pain control and cartilage repair. Journal of Biomedical Materials Research Part B: Applied Biomaterials 101:8, pages 1508-1515.
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J. Brian McAlvin, Gally Reznor, Sahadev A. Shankarappa, Cristina F. Stefanescu & Daniel S. Kohane. (2013) Local Toxicity from Local Anesthetic Polymeric Microparticles. Anesthesia & Analgesia 116:4, pages 794-803.
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