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Expert Opinion on Investigational Drugs Volume 20, 2011 - Issue 10
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Blocking the interaction of vascular endothelial growth factor receptors with their ligands and their effector signaling as a novel therapeutic target for cancer: time for a new look?

David BruceOxford University, Nuffield Department of Surgical Science, The John Radcliffe, Headley Way, Oxford, Oxon, OX3 9DU, UK
&
Peng H TanOxford University, Nuffield Department of Surgical Science, The John Radcliffe, Headley Way, Oxford, Oxon, OX3 9DU, UK; Charing Cross Hospital, Imperial College London, Breast Care Unit, Fulham Palace Road, London, W6 8RF, UK+44 0 20 33117624; [email protected]
Pages 1413-1434 | Published online: 25 Aug 2011

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Lizbeth Robles Irizarry, Dolores Hambardzumyan, Ichiro Nakano, Candece L Gladson & Manmeet S Ahluwalia. (2012) Therapeutic targeting of VEGF in the treatment of glioblastoma. Expert Opinion on Therapeutic Targets 16:10, pages 973-984.
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Articles from other publishers (9)

Bhagyashri Chaudhari, Harun Patel, Snehal Thakar, Iqrar Ahmad & Deepali Bansode. (2022) Optimizing the Sunitinib for cardio-toxicity and thyro-toxicity by scaffold hopping approach. In Silico Pharmacology 10:1.
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Mohammad Malekan & Mohammad Ali Ebrahimzadeh. (2022) Vascular Endothelial Growth Factor Receptors [VEGFR] as Target in Breast Cancer Treatment: Current Status in Preclinical and Clinical Studies and Future Directions. Current Topics in Medicinal Chemistry 22:11, pages 891-920.
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Sabya Sachi Das, Saad Alkahtani, Priyanshu Bharadwaj, Mohammed Tahir Ansari, Muneera D.F. ALKahtani, Zhiqing Pang, Md Saquib Hasnain, Amit Kumar Nayak & Tejraj M. Aminabhavi. (2020) Molecular insights and novel approaches for targeting tumor metastasis. International Journal of Pharmaceutics 585, pages 119556.
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Khalid A. Mohamedali, Yu Cao, Lawrence H. Cheung, Walter N. Hittelman & Michael G. Rosenblum. (2013) The Functionalized Human Serine Protease Granzyme B/VEGF121 Targets Tumor Vasculature and Ablates Tumor Growth. Molecular Cancer Therapeutics 12:10, pages 2055-2066.
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Kazuhisa Ishimoto, Yasuhiro Sawai, Naohiro Fukuda, Toshiaki Nagata & Tomomi Ikemoto. (2013) Convergent and streamlined synthesis of 6-etherified imidazo[1,2-b]pyridazine-2-amine derivatives possessing VEGFR-2 kinase inhibitory activity. Tetrahedron 69:40, pages 8564-8571.
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David J. Bruce & Peng H. Tan. 2013. Biochemical Basis and Therapeutic Implications of Angiogenesis. Biochemical Basis and Therapeutic Implications of Angiogenesis 3 22 .
Ronit Freeman, Julia Girsh, Amily Fang-ju Jou, Ja-an Annie Ho, Thomas Hug, Jens Dernedde & Itamar Willner. (2012) Optical Aptasensors for the Analysis of the Vascular Endothelial Growth Factor (VEGF). Analytical Chemistry 84:14, pages 6192-6198.
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Mallika Singh & Napoleone Ferrara. (2012) Modeling and predicting clinical efficacy for drugs targeting the tumor milieu. Nature Biotechnology 30:7, pages 648-657.
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Juan Zhang, Haixin Li, Xiuyun Wang, Haidi Qi, Xiaoniu Miao, Tao Zhang, Guosheng Chen & Min Wang. (2012) Phage-derived fully human antibody scFv fragment directed against human vascular endothelial growth factor receptor 2 blocked its interaction with VEGF. Biotechnology Progress 28:4, pages 981-989.
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