Advanced search
Publication Cover
Expert Opinion on Investigational Drugs Volume 20, 2011 - Issue 12
Submit an article Journal homepage
375
Views
11
CrossRef citations to date
0
Altmetric
Reviews

Investigational Notch and Hedgehog inhibitors – therapies for cardiovascular disease

Eileen M RedmondUniversity of Rochester, Department of Surgery, 601 Elmwood Ave, Box SURG, Rochester, NY 14642, USA
,
Shaunta GuhaKing's College London, Department of Cardiology, James Black Centre 125 Coldharbour Lane, London SE5 9NU, UK
,
Dermot WallsDublin City University, School of Biotechnology, National Centre for Sensor Research, Glasnevin, Dublin 9, Ireland
&
Paul A CahillDublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland+3531 700 8466; +3531 700 5412; [email protected]
Pages 1649-1664 | Published online: 18 Oct 2011

Citations (11)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Noopur Sinha, Saikat Chowdhury & Ram Rup Sarkar. (2018) Deciphering structural stability and binding mechanisms of potential antagonists with smoothened protein. Journal of Biomolecular Structure and Dynamics 36:11, pages 2917-2937.
Read now

Articles from other publishers (10)

Jun LiYazhou HanMingduo LiCaixia Nie. (2019) Curcumin Promotes Proliferation of Adult Neural Stem Cells and the Birth of Neurons in Alzheimer's Disease Mice via Notch Signaling Pathway. Cellular Reprogramming 21:3, pages 152-161.
Crossref
Jessica Davis-Knowlton, Jacqueline E. Turner, Anna Turner, Sydney Damian-Loring, Nicholas Hagler, Terry Henderson, Ivette F. Emery, Kyle Bond, Christine W. Duarte, Calvin P.H. Vary, Jens Eldrup-Jorgensen & Lucy Liaw. (2019) Characterization of smooth muscle cells from human atherosclerotic lesions and their responses to Notch signaling. Laboratory Investigation 99:3, pages 290-304.
Crossref
Irundika H.K. Dias, Ivana Milic, Gregory Y.H. Lip, Andrew Devitt, M. Cristina Polidori & Helen R. Griffiths. (2018) Simvastatin reduces circulating oxysterol levels in men with hypercholesterolaemia. Redox Biology 16, pages 139-145.
Crossref
Guanghai Jin, Aneesh Sivaraman & Kyeong Lee. (2017) Development of taladegib as a sonic hedgehog signaling pathway inhibitor. Archives of Pharmacal Research 40:12, pages 1390-1393.
Crossref
Xianjun Zhang, Fei Zhao, Yiran Wu, Jun Yang, Gye Won Han, Suwen Zhao, Andrii Ishchenko, Lintao Ye, Xi Lin, Kang Ding, Venkatasubramanian Dharmarajan, Patrick R. Griffin, Cornelius Gati, Garrett Nelson, Mark S. Hunter, Michael A. Hanson, Vadim Cherezov, Raymond C. Stevens, Wenfu Tan, Houchao Tao & Fei Xu. (2017) Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand. Nature Communications 8:1.
Crossref
Bethany A. Kerr, Xiaoxia Z. West, Young-Woong Kim, Yongzhong Zhao, Miroslava Tischenko, Rebecca M. Cull, Timothy W. Phares, Xiao-Ding Peng, Jeremiah Bernier-Latmani, Tatiana V. Petrova, Ralf H. Adams, Nissim Hay, Sathyamangla V. Naga Prasad & Tatiana V. Byzova. (2016) Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium. Nature Communications 7:1.
Crossref
Yury S. Tarahovsky, Yuri A. Kim, Elena A. Yagolnik & Eugeny N. Muzafarov. (2014) Flavonoid–membrane interactions: Involvement of flavonoid–metal complexes in raft signaling. Biochimica et Biophysica Acta (BBA) - Biomembranes 1838:5, pages 1235-1246.
Crossref
Joshua M. BoucherAnne HarringtonBahman RostamaVolkhard LindnerLucy Liaw. (2013) A Receptor-Specific Function for Notch2 in Mediating Vascular Smooth Muscle Cell Growth Arrest Through Cyclin-dependent Kinase Inhibitor 1B. Circulation Research 113:8, pages 975-985.
Crossref
. (2012) Current World Literature. Current Opinion in Organ Transplantation 17:6, pages 688-699.
Crossref
Larry A. Greenbaum, Rainer Benndorf & William E. Smoyer. (2012) Childhood nephrotic syndrome—current and future therapies. Nature Reviews Nephrology 8:8, pages 445-458.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.