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Expert Opinion on Investigational Drugs Volume 21, 2012 - Issue 2
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Drug Evaluations

Apaziquone as an intravesical therapeutic agent for urothelial non-muscle-invasive bladder cancer

Vladimir YutkinUniversity of Western Ontario, Schulich School of Medicine & Dentistry, London Health Sciences Centre–Victoria Hospital, Division of Urology, Department of Surgery, 800 Commissioners Road East, Room C3-120, London, Ontario N6A 5W9, Canada+519 685 8451; +519 685 8455; [email protected]
, MD &
Joseph ChinUniversity of Western Ontario, Schulich School of Medicine & Dentistry, London Health Sciences Centre–Victoria Hospital, Division of Urology, Department of Surgery, 800 Commissioners Road East, Room C3-120, London, Ontario N6A 5W9, Canada+519 685 8451; +519 685 8455; [email protected]
, MD
Pages 251-260 | Published online: 21 Dec 2011

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R. M. Phillips, H. R. Hendriks, J. B. Sweeney, G. Reddy & G. J. Peters. (2017) Efficacy, pharmacokinetic and pharmacodynamic evaluation of apaziquone in the treatment of non-muscle invasive bladder cancer. Expert Opinion on Drug Metabolism & Toxicology 13:7, pages 783-791.
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Anna V van Lingen, Tom JH Arends & J Alfred Witjes. (2013) Expert review: an update in current and developing intravesical therapies for non-muscle-invasive bladder cancer. Expert Review of Anticancer Therapy 13:11, pages 1257-1268.
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Willem Oosterlinck & Karel Decaestecker. (2012) Current strategies in the treatment of non-muscle-invasive bladder cancer. Expert Review of Anticancer Therapy 12:8, pages 1097-1106.
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Articles from other publishers (9)

Nora Astrain-Redin, Carmen Sanmartin, Arun K. Sharma & Daniel Plano. (2023) From Natural Sources to Synthetic Derivatives: The Allyl Motif as a Powerful Tool for Fragment-Based Design in Cancer Treatment. Journal of Medicinal Chemistry 66:6, pages 3703-3731.
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Adamshafi Shaik, Allaka Tejeswara Rao, S.V.M. Mohan Rao & Pilli V.V.N. Kishore. (2021) Synthesis of Biologically Active Novel Indole Fused Heterocyclic Derivatives: Molecular Modeling Studies. Asian Journal of Chemistry 33:7, pages 1677-1684.
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Sayan Pramanik, Suvendu Maity, Prasanta Ghosh & Chhanda Mukhopadhyay. (2019) Acid-promoted multicomponent allylic amidation towards 7-acetamido tetrahydroindole derivatives. Tetrahedron Letters 60:5, pages 435-438.
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Shengtao Xu, Hong Yao, Lingling Pei, Mei Hu, Dahong Li, Yangyi Qiu, Guangyu Wang, Liang Wu, Hequan Yao, Zheying Zhu & Jinyi Xu. (2017) Design, synthesis, and biological evaluation of NAD(P)H: Quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing indolequinone moiety for hypoxia-selective activation. European Journal of Medicinal Chemistry 132, pages 310-321.
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Monikaben Padariya & Umesh Kalathiya. (2016) Structure-based design and evaluation of novel N-phenyl-1H-indol-2-amine derivatives for fat mass and obesity-associated (FTO) protein inhibition. Computational Biology and Chemistry 64, pages 414-425.
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Gunjan Srivastava, Raj Thani Somasundaram, Paul G. Walfish & Ranju Ralhan. (2015) Anticancer Activity of Apaziquone in Oral Cancer Cells and Xenograft Model: Implications for Oral Cancer Therapy. PLOS ONE 10:7, pages e0133735.
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Nagendra Kaushik, Neha Kaushik, Pankaj Attri, Naresh Kumar, Chung Kim, Akhilesh Verma & Eun Choi. (2013) Biomedical Importance of Indoles. Molecules 18:6, pages 6620-6662.
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David C. Johnson, Raj S. Pruthi & Michael E. Woods. (2013) Perioperative Chemotherapy. Urologic Clinics of North America 40:2, pages 183-195.
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Callum Logan, Matthew Brown & Dickon Hayne. (2012) Intravesical therapies for bladder cancer - indications and limitations. BJU International 110, pages 12-21.
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