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Expert Opinion on Investigational Drugs Volume 21, 2012 - Issue 12
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Reviews

JAK2 inhibitors in the treatment of myeloproliferative neoplasms

Raoul TibesDivision of Hematology and Oncology, Mayo Clinic, 13400 E. Shea Blvd, Scottsdale, AZ 85259, USA480 301 4502;480 301 4675;[email protected]
,
James M BogenbergerDivision of Hematology and Oncology, Mayo Clinic, 13400 E. Shea Blvd, Scottsdale, AZ 85259, USA480 301 4502;480 301 4675;[email protected]
,
Holly L GeyerMayo Clinic, Hospital Internal Medicine, 13400 E. Shea Blvd, Scottsdale, AZ 85259, USA
&
Ruben A MesaMayo Clinic, Hematology, 200 First Street SW, Rochester, MN 55905, USA
Pages 1755-1774 | Published online: 19 Sep 2012

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Read on this site (2)

Adriana Zámečníkova. (2014) Novel approaches to the development of tyrosine kinase inhibitors and their role in the fight against cancer. Expert Opinion on Drug Discovery 9:1, pages 77-92.
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Raoul Tibes & Ruben A Mesa. (2013) Emerging drugs for polycythemia vera. Expert Opinion on Emerging Drugs 18:3, pages 393-404.
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Articles from other publishers (10)

Mi-Ae Kang, Jongsung Lee, Sang Ha, Chang Lee, Kyoung Kim, Kyu Jang & See-Hyoung Park. (2019) Interleukin4Rα (IL4Rα) and IL13Rα1 Are Associated with the Progress of Renal Cell Carcinoma through Janus Kinase 2 (JAK2)/Forkhead Box O3 (FOXO3) Pathways. Cancers 11:9, pages 1394.
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R Tamari, T I Mughal, D Rondelli, R Hasserjian, V Gupta, O Odenike, V Fauble, G Finazzi, F Pane, J Mascarenhas, J Prchal, S Giralt & R Hoffman. (2015) Allo-SCT for myelofibrosis: reversing the chronic phase in the JAK inhibitor era?. Bone Marrow Transplantation 50:5, pages 628-636.
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Chao Zhao, Su Hui Yang, Daulat Bikram Khadka, Yifeng Jin, Kyung-Tae Lee & Won-Jea Cho. (2015) Computer-aided discovery of aminopyridines as novel JAK2 inhibitors. Bioorganic & Medicinal Chemistry 23:5, pages 985-995.
Crossref
Raoul Tibes & Ruben A Mesa. (2014) Targeting hedgehog signaling in myelofibrosis and other hematologic malignancies. Journal of Hematology & Oncology 7:1.
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SHU-WEI WANG, JUN HU, QIN-HAO GUO, YAN ZHAO, JIE-JING CHENG, DONG-SHENG ZHANG, QIANG FEI, JUAN LI & YUE-MING SUN. (2014) AZD1480, a JAK inhibitor, inhibits cell growth and survival of colorectal cancer via modulating the JAK2/STAT3 signaling pathway. Oncology Reports 32:5, pages 1991-1998.
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Jamie Williams, Kirsten Munro & Timothy Palmer. (2014) Role of Ubiquitylation in Controlling Suppressor of Cytokine Signalling 3 (SOCS3) Function and Expression. Cells 3:2, pages 546-562.
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Lei Gu, Pooja Talati, Paraskevi Vogiatzi, Ana L. Romero-Weaver, Junaid Abdulghani, Zhiyong Liao, Benjamin Leiby, David T. Hoang, Tuomas Mirtti, Kalle Alanen, Michael Zinda, Dennis Huszar & Marja T. Nevalainen. (2014) Pharmacologic Suppression of JAK1/2 by JAK1/2 Inhibitor AZD1480 Potently Inhibits IL-6–Induced Experimental Prostate Cancer Metastases Formation. Molecular Cancer Therapeutics 13:5, pages 1246-1258.
Crossref
Bernd Groner & Astrid Weiss. (2013) Targeting Survivin in Cancer: Novel Drug Development Approaches. BioDrugs 28:1, pages 27-39.
Crossref
A. Mortlock, K. Foote, J. Kettle & B. Aquila. 2014. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering.
Chi-Tai Yeh, Wen-Chien Huang, Yerra Koteswara Rao, Min Ye, Wei-Hwa Lee, Liang-Shun Wang, David T.W. Tzeng, Chih-Hsiung Wu, Yi-Shing Shieh, Chi-Ying F. Huang, Yu-Jen Chen, Michael Hsiao, Alexander T.H. Wu, Zhen Yang & Yew-Min Tzeng. (2013) A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells. Carcinogenesis 34:12, pages 2918-2928.
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