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Investigational FMS-like tyrosine kinase 3 inhibitors in treatment of acute myeloid leukemia

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Courtney D DiNardo & Jorge E Cortes. (2015) New treatment for acute myelogenous leukemia. Expert Opinion on Pharmacotherapy 16:1, pages 95-106.
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Yue Zhong, Run-Ze Qiu, Shan-Liang Sun, Chao Zhao, Tian-Yuan Fan, Min Chen, Nian-Guang Li & Zhi-Hao Shi. (2020) Small-Molecule Fms-like Tyrosine Kinase 3 Inhibitors: An Attractive and Efficient Method for the Treatment of Acute Myeloid Leukemia. Journal of Medicinal Chemistry 63:21, pages 12403-12428.
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Khalil Saleh, Nadine Khalifeh-Saleh & Hampig Raphael Kourie. (2020) Acute myeloid leukemia transformed to a targetable disease. Future Oncology 16:14, pages 961-972.
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Daniel A. Pollyea. (2018) Which novel agents for acute myeloid leukemia are likely to change practice?. Best Practice & Research Clinical Haematology 31:4, pages 391-395.
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Daniel A. Pollyea. (2018) New drugs for acute myeloid leukemia inspired by genomics and when to use them. Hematology 2018:1, pages 45-50.
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Mark C. Weir, Sherry T. Shu, Ravi K. Patel, Sabine Hellwig, Li Chen, Li Tan, Nathanael S. Gray & Thomas E. Smithgall. (2018) Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo . ACS Chemical Biology 13:6, pages 1551-1559.
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Shanhao Tang, Hongjie Shen, Xinliang Mao, Haiping Dai, Xiaming Zhu, Shengli Xue, Zixuan Ding, Jing Lu, Depei Wu & Xiaowen Tang. (2017) FLT3-ITD with DNMT3A R882 double mutation is a poor prognostic factor in Chinese patients with acute myeloid leukemia after chemotherapy or allogeneic hematopoietic stem cell transplantation. International Journal of Hematology 106:4, pages 552-561.
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Kate McArthur, Akshay A. D’Cruz, David Segal, Kurt Lackovic, Andrew F. Wilks, Joanne A. O’Donnell, Cameron J. Nowell, Motti Gerlic, David C.S. Huang, Christopher J. Burns & Ben A. Croker. (2017) Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia. Oncotarget 8:35, pages 57948-57963.
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Singkome Tima, Siriporn Okonogi, Chadarat Ampasavate, Chad Pickens, Cory Berkland & Songyot Anuchapreeda. (2016) Development and Characterization of FLT3-Specific Curcumin-Loaded Polymeric Micelles as a Drug Delivery System for Treating FLT3-Overexpressing Leukemic Cells. Journal of Pharmaceutical Sciences 105:12, pages 3645-3657.
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Marlise R. Luskin, Phyllis A. Gimotty, Catherine Smith, Alison W. Loren, Maria E. Figueroa, Jenna Harrison, Zhuoxin Sun, Martin S. Tallman, Elisabeth M. Paietta, Mark R. Litzow, Ari M. Melnick, Ross L. Levine, Hugo F. Fernandez, Selina M. Luger, Martin Carroll, Stephen R. Master & Gerald B.W. Wertheim. (2016) A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia. JCI Insight 1:9.
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Naveen Pemmaraju, Hagop Kantarjian, Farhad Ravandi, Graciela M. Nogueras-Gonzalez, Xuelin Huang, Susan O'Brien, William Wierda, Guillermo Garcia-Manero, Deborah Thomas, Sherry Pierce, Srdan Verstovsek, Gautam Borthakur & Jorge Cortes. (2016) Patient Characteristics and Outcomes in Adolescents and Young Adults (AYA) With Acute Myeloid Leukemia (AML). Clinical Lymphoma Myeloma and Leukemia 16:4, pages 213-222.e2.
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Harinder Gill, Anskar Leung & Yok-Lam Kwong. (2016) Molecular and Cellular Mechanisms of Myelodysplastic Syndrome: Implications on Targeted Therapy. International Journal of Molecular Sciences 17:4, pages 440.
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Harinder Gill, Anskar YH Leung & Yok-Lam Kwong. (2016) Molecularly targeted therapy in acute myeloid leukemia. Future Oncology 12:6, pages 827-838.
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Elisa Zuffa, Eugenia Franchini, Cristina Papayannidis, Carmen Baldazzi, Giorgia Simonetti, Nicoletta Testoni, Maria Chiara Abbenante, Stefania Paolini, Chiara Sartor, Sarah Parisi, Giovanni Marconi, Federica Cattina, Maria Teresa Bochicchio, Claudia Venturi, Emanuela Ottaviani, Michele Cavo & Giovanni Martinelli. (2015) Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients. Oncotarget 6:31, pages 31284-31294.
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Rimma Berenstein. (2015) Class III Receptor Tyrosine Kinases in Acute Leukemia – Biological Functions and Modern Laboratory Analysis. Biomarker Insights 10s3, pages BMI.S22433.
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Naveen Pemmaraju, Hagop Kantarjian, Guillermo Garcia-Manero, Sherry Pierce, Marylou Cardenas-Turanzas, Jorge Cortes & Farhad Ravandi. (2015) Improving outcomes for patients with acute myeloid leukemia in first relapse: A single center experience. American Journal of Hematology 90:1, pages 27-30.
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