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Modulation of autophagy for the treatment of liver diseases

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Enwei Wei, Sixi Zhang, Jinghui Zhai, Sitong Wu & Guangshu Wang. (2022) The evaluation of hepatoprotective effects of flavonoids from Scorzonera austriaca Wild against CCl4-induced acute liver injury in vitro and in vivo. Drug and Chemical Toxicology 45:3, pages 1284-1294.
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Yuqing Mao, Fujun Yu, Jianbo Wang, Chuanyong Guo & Xiaoming Fan. (2016) Autophagy: a new target for nonalcoholic fatty liver disease therapy. Hepatic Medicine: Evidence and Research 8, pages 27-37.
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Peter Hauff, Ulrich Gottwald & Matthias Ocker. (2015) Early to Phase II drugs currently under investigation for the treatment of liver fibrosis. Expert Opinion on Investigational Drugs 24:3, pages 309-327.
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Articles from other publishers (26)

Weigang Yuan, Fenglei Jian & Yueguang Rong. (2022) Bifendate inhibits autophagy at multiple steps and attenuates oleic acid-induced lipid accumulation. Biochemical and Biophysical Research Communications 631, pages 115-123.
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Liwei Wu, Qiang Yu, Ping Cheng & Chuanyong Guo. (2021) PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway. PPAR Research 2021, pages 1-15.
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Shanshan Wang, Yu Sun, Yang Wang, Anna Wang, Buxin Kou, Yang Che, Dexi Chen, Yulin Zhang & Ying Shi. (2021) ASPP2 inhibits hepatitis B virus replication by preventing nucleus translocation of HSF1 and attenuating the transactivation of ATG7. Journal of Cellular and Molecular Medicine 25:14, pages 6899-6908.
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Dina Zakaria Mohamed, Alaa El-Din El-Sayed El-Sisi, Samia Salim Sokar, Abdelhadi Mohamed Shebl & Sally El-Sayed Abu-Risha. (2021) Targeting autophagy to modulate hepatic ischemia/reperfusion injury: A comparative study between octreotide and melatonin as autophagy modulators through AMPK/PI3K/AKT/mTOR/ULK1 and Keap1/Nrf2 signaling pathways in rats. European Journal of Pharmacology 897, pages 173920.
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Elias Kouroumalis, Argryro Voumvouraki, Aikaterini Augoustaki & Dimitrios N Samonakis. (2021) Autophagy in liver diseases. World Journal of Hepatology 13:1, pages 6-65.
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Tzu-Min Hung, Chih-Chiang Hsiao, Chih-Wen Lin & Po-Huang Lee. (2020) Complex Cell Type-Specific Roles of Autophagy in Liver Fibrosis and Cirrhosis. Pathogens 9:3, pages 225.
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Juan Zheng, Ting Chen, Xin Guo, James M. Ntambi & Chaodong Wu. 2020. Lipid Signaling and Metabolism. Lipid Signaling and Metabolism 273 295 .
Jia Fan, Yinghong Shi & Yuanfei Peng. 2020. Autophagy: Biology and Diseases. Autophagy: Biology and Diseases 497 528 .
Hai-chang Yin, Shu-li Shao, Xin-jie Jiang, Peng-yu Xie, Wan-shu Sun & Tian-fei Yu. (2019) Interactions between Autophagy and DNA Viruses. Viruses 11:9, pages 776.
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Tzu-Min Hung, Yu-Jen Huang, Yu-Chun Lin, Yu-Hsuan Chen, Yao-Ming Wu & Po-Huang Lee. (2019) A critical role of autophagy in regulating the mesenchymal transition of ductular cells in liver cirrhosis. Scientific Reports 9:1.
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Rumeng Tan, Hongzhe Tian, Bo Yang, Bo Zhang, Chen Dai, Zhenyi Han, Meixi Wang, Yakun Li, Lai Wei, Dong Chen, Guangyao Wang, Huifang Yang, Fan He & Zhishui Chen. (2018) Autophagy and Akt in the protective effect of erythropoietin helix B surface peptide against hepatic ischaemia/reperfusion injury in mice. Scientific Reports 8:1.
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Nicholas J. Hunt, Peter A.G. McCourt, David G. Le Couteur & Victoria C. Cogger. (2018) Novel targets for delaying aging: The importance of the liver and advances in drug delivery. Advanced Drug Delivery Reviews 135, pages 39-49.
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Ricky H. Bhogal, Christopher J. Weston, Susanne Velduis, Henri G. D. Leuvenink, Gary M. Reynolds, Scott Davies, Luu Nyguet‐Thin, Mohammed Alfaifi, Emma L. Shepard, Yuri Boteon, Lorraine Wallace, Ye H. Oo, David H. Adams, Darius F. Mirza, Hynek Mergental, Gillian Muirhead, Barnaby T. F. Stephenson & Simon C. Afford. (2018) The Reactive Oxygen Species–Mitophagy Signaling Pathway Regulates Liver Endothelial Cell Survival During Ischemia/Reperfusion Injury. Liver Transplantation 24:10, pages 1437-1452.
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Mingjie Xie, Zhenggang Yang, Yanning Liu & Min Zheng. (2018) The role of HBV-induced autophagy in HBV replication and HBV related-HCC. Life Sciences 205, pages 107-112.
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Xun Wang, Shuai Wang, Yuan Zhou, Halmurat Obulkasim, Zhi‑Heng Zhang, Bo Dai, Wei Zhu & Xiao‑Lei Shi. (2018) BM‑MSCs protect against liver ischemia/reperfusion injury via HO‑1 mediated autophagy. Molecular Medicine Reports.
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Cong Liu, Lian Liu, Hai-Dan Zhu, Jia-Qi Sheng, Xiao-Li Wu, Xing-Xing He, De-An Tian, Jia-Zhi Liao & Pei-Yuan Li. (2018) Celecoxib alleviates nonalcoholic fatty liver disease by restoring autophagic flux. Scientific Reports 8:1.
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Brijesh Kumar Singh, Rohit Anthony Sinha, Kenji Ohba & Paul Michael Yen. (2017) Role of thyroid hormone in hepatic gene regulation, chromatin remodeling, and autophagy. Molecular and Cellular Endocrinology 458, pages 160-168.
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Shengmin Yan, Nazmul Huda, Bilon Khambu & Xiao-Ming Yin. (2017) Relevance of autophagy to fatty liver diseases and potential therapeutic applications. Amino Acids 49:12, pages 1965-1979.
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Linmao Zhong, Wangqin Shu, Wangbin Dai, Bo Gao & Sidong Xiong. (2017) Reactive Oxygen Species-Mediated c-Jun NH 2 -Terminal Kinase Activation Contributes to Hepatitis B Virus X Protein-Induced Autophagy via Regulation of the Beclin-1/Bcl-2 Interaction . Journal of Virology 91:15.
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Junjie Lan, Ning Wang, Lan Huang, Yazhou Liu, Xiaopan Ma, Huayong Lou, Chao Chen, Yibin Feng & Weidong Pan. (2017) Design and synthesis of novel tetrandrine derivatives as potential anti-tumor agents against human hepatocellular carcinoma. European Journal of Medicinal Chemistry 127, pages 554-566.
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Cong Liu, Jia-Zhi Liao & Pei-Yuan Li. (2017) Traditional Chinese herbal extracts inducing autophagy as a novel approach in therapy of nonalcoholic fatty liver disease. World Journal of Gastroenterology 23:11, pages 1964.
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Sergi Guixé-Muntet, Fernanda Cristina de Mesquita, Sergi Vila, Virginia Hernández-Gea, Carmen Peralta, Juan Carlos García-Pagán, Jaime Bosch & Jordi Gracia-Sancho. (2017) Cross-talk between autophagy and KLF2 determines endothelial cell phenotype and microvascular function in acute liver injury. Journal of Hepatology 66:1, pages 86-94.
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Li-li Gong, Guang-run Li, Wen Zhang, He Liu, Ya-li Lv, Fei-fei Han, Zi-rui Wan, Ming-biao Shi & Li-hong Liu. (2016) Akebia Saponin D Decreases Hepatic Steatosis through Autophagy Modulation. Journal of Pharmacology and Experimental Therapeutics 359:3, pages 392-400.
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Perinur Bozaykut, Ali Sahin, Betul Karademir & Nesrin Kartal Ozer. (2016) Endoplasmic reticulum stress related molecular mechanisms in nonalcoholic steatohepatitis. Mechanisms of Ageing and Development 157, pages 17-29.
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L Zhong, J Hu, W Shu, B Gao & S Xiong. (2015) Epigallocatechin-3-gallate opposes HBV-induced incomplete autophagy by enhancing lysosomal acidification, which is unfavorable for HBV replication. Cell Death & Disease 6:5, pages e1770-e1770.
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Lei Zhan, Yang Yang, Tao-Tao Ma, Cheng Huang, Xiao-Ming Meng, Lei Zhang & Jun Li. (2015) Transient receptor potential vanilloid 4 inhibits rat HSC-T6 apoptosis through induction of autophagy. Molecular and Cellular Biochemistry 402:1-2, pages 9-22.
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