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Expert Opinion on Investigational Drugs Volume 23, 2014 - Issue 7
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Drug Evaluations

Serelaxin: a potential new drug for the treatment of acute heart failure

Natalia NeverovaUniversity of California San Francisco, Department of Medicine, San Francisco, CA, USA
&
John R TeerlinkUniversity of California San Francisco, Department of Medicine, San Francisco, CA, USA;San Francisco Veterans Affairs Medical Center, Section of Cardiology, 4150 Clement Street, San Francisco, CA 94131, USA+1 415 221 4810; [email protected]
Pages 1017-1026 | Published online: 28 May 2014

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Read on this site (4)

Justyna Krzysztofik & Piotr Ponikowski. (2017) Current and emerging pharmacologic options for the management of patients with chronic and acute decompensated heart failure. Expert Review of Clinical Pharmacology 10:5, pages 517-534.
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Hao A. Tran, Felice Lin & Barry H. Greenberg. (2016) Potential new drug treatments for congestive heart failure. Expert Opinion on Investigational Drugs 25:7, pages 811-826.
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Peter Hauff, Ulrich Gottwald & Matthias Ocker. (2015) Early to Phase II drugs currently under investigation for the treatment of liver fibrosis. Expert Opinion on Investigational Drugs 24:3, pages 309-327.
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Renato De Vecchis & Cesare Baldi. (2014) Cardiorenal syndrome type 2: from diagnosis to optimal management. Therapeutics and Clinical Risk Management 10, pages 949-961.
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Articles from other publishers (7)

Rafael Clara Martins, Mariana Pintalhão, Adelino Leite-Moreira & Paulo Castro-Chaves. (2020) Relaxin and the Cardiovascular System: from Basic Science to Clinical Practice. Current Molecular Medicine 20:3, pages 167-184.
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Teja Devarakonda & Fadi N. Salloum. (2018) Heart Disease and Relaxin: New Actions for an Old Hormone. Trends in Endocrinology & Metabolism 29:5, pages 338-348.
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Juan Valle Raleigh, Adolfo G. Mauro, Teja Devarakonda, Carlo Marchetti, Jun He, Erica Kim, Scott Filippone, Anindita Das, Stefano Toldo, Antonio Abbate & Fadi N. Salloum. (2017) Reperfusion therapy with recombinant human relaxin-2 (Serelaxin) attenuates myocardial infarct size and NLRP3 inflammasome following ischemia/reperfusion injury via eNOS-dependent mechanism. Cardiovascular Research, pages cvw246.
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Robert G. Gourdie, Stefanie Dimmeler & Peter Kohl. (2016) Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease. Nature Reviews Drug Discovery 15:9, pages 620-638.
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Chrishan S. Samuel, Roger J. Summers & Tim D. Hewitson. (2016) Antifibrotic Actions of Serelaxin – New Roles for an Old Player. Trends in Pharmacological Sciences 37:6, pages 485-497.
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Alessandro Pini, Giulia Boccalini, Maria Caterina Baccari, Matteo Becatti, Rachele Garella, Claudia Fiorillo, Laura Calosi, Daniele Bani & Silvia Nistri. (2016) Protection from cigarette smoke-induced vascular injury by recombinant human relaxin-2 (serelaxin). Journal of Cellular and Molecular Medicine 20:5, pages 891-902.
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James A. Iwaz, Elizabeth Lee, Hermineh Aramin, Danilo Romero, Navaid Iqbal, Matt Kawahara, Fatima Khusro, Brian Knight, Minal V. Patel, Sumita Sharma & Alan S. Maisel. (2015) New Targets in the Drug Treatment of Heart Failure. Drugs 76:2, pages 187-201.
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