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Discontinued Drug Perspective

Inflammatory bowel disease therapies discontinued between 2009 and 2014

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Ole Haagen Nielsen, Jakob Benedict Seidelin, Mark Ainsworth & Mehmet Coskun. (2016) Will novel oral formulations change the management of inflammatory bowel disease?. Expert Opinion on Investigational Drugs 25:6, pages 709-718.
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Yuki Hayashi & Hiroshi Nakase. (2022) The Molecular Mechanisms of Intestinal Inflammation and Fibrosis in Crohn’s Disease. Frontiers in Physiology 13.
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Galal H. Elgemeie, Rasha A. Azzam, Wafaa A. Zaghary, Ashraf A. Aly, Nadia H. Metwally, Mona O. Sarhan, Elshimaa M. Abdelhafez & Rasha E. Elsayed. 2022. N-Sulfonated-N-Heterocycles. N-Sulfonated-N-Heterocycles 447 496 .
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Cheng Zhao, Xiaoming Kao, Zhiwei Wang, Qinjie Liu, Jie Wu, Qiongyuan Hu, Xiuwen Wu & Jianan Ren. (2020) Biomimetic enzyme barrier for preventing intestine-derived LPS induced diseases. RSC Advances 10:15, pages 9126-9132.
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Philip Mease, Euthalia Roussou, Gerd-Rüdiger Burmester, Philippe Goupille, Alice Gottlieb, Susan R. Moriarty, Olivier Benichou, David H. Adams, Wen Xu & Peter Nash. (2019) Safety of Ixekizumab in Patients With Psoriatic Arthritis: Results From a Pooled Analysis of Three Clinical Trials. Arthritis Care & Research 71:3, pages 367-378.
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Luca Di Martino, Abdullah Osme, Sarah Kossak-Gupta, Theresa T. Pizarro & Fabio Cominelli. (2019) TWEAK/Fn14 Is Overexpressed in Crohn’s Disease and Mediates Experimental Ileitis by Regulating Critical Innate and Adaptive Immune Pathways. Cellular and Molecular Gastroenterology and Hepatology 8:3, pages 427-446.
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Anthony So & Robert Davies Inman. (2018) An overview of biologic disease-modifying antirheumatic drugs in axial spondyloarthritis and psoriatic arthritis. Best Practice & Research Clinical Rheumatology 32:3, pages 453-471.
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Sahil Sekhon, Caleb Jeon & Wilson Liao. 2018. Evidence-Based Psoriasis. Evidence-Based Psoriasis 73 92 .
Bruce Strober, Craig Leonardi, Kim A. Papp, Ulrich Mrowietz, Mamitaro Ohtsuki, Robert Bissonnette, Laura K. Ferris, Carle Paul, Mark Lebwohl, Daniel K. Braun, Lotus Mallbris, Stefan Wilhelm, Wen Xu, Anders Ljungberg, Nayan Acharya & Kristian Reich. (2017) Short- and long-term safety outcomes with ixekizumab from 7 clinical trials in psoriasis: Etanercept comparisons and integrated data. Journal of the American Academy of Dermatology 76:3, pages 432-440.e17.
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Clara Abraham, Parambir S. Dulai, Séverine Vermeire & William J. Sandborn. (2017) Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases. Gastroenterology 152:2, pages 374-388.e4.
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Dhavalkumar D. Patel & Vijay K. Kuchroo. (2015) Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions. Immunity 43:6, pages 1040-1051.
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