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Expert Opinion on Investigational Drugs Volume 24, 2015 - Issue 9
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Review

An overview of early investigational therapies for chemoresistant ovarian cancer

Claudia MarchettiUniversity of Rome “Sapienza”, Department of Gynecological and Obstetrical Sciences and Urological Sciences, Viale del Policlinico, Rome, Italy
, MD (Clinical Research Fellow in Gynecological Oncology) ,
Jonathan A LedermannUniversity College London, UCL Cancer Institute, Cancer Research UK and University College London Cancer Trials Centre, 90 Tottenham Court Road, London, UK
, BSc MD FRCP (Professor of Medical Oncology UCL Cancer Institute, Clinical Director, UCL Cancer Institute & Director) &
Pierluigi Benedetti PaniciProfessor of Gynecological Oncology and Gynecological Sciences at “Sapienza” University, Rome; Director Department of Gynecologic Oncology, University of Rome “Sapienza”, Department of Gynecological and Obstetrical Sciences and Urological Sciences, Viale del Policlinico, Rome, [email protected];University College London, UCL Cancer Institute, Cancer Research UK and University College London Cancer Trials Centre, 90 Tottenham Court Road, London, UK
, MD
Pages 1163-1183 | Published online: 24 Jul 2015

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Federica Tomao, Claudia Marchetti, Alessia Romito, Anna Di Pinto, Violante Di Donato, Oriana Capri, Innocenza Palaia, Marco Monti, Ludovico Muzii & Pierluigi Benedetti Panici. (2017) Overcoming platinum resistance in ovarian cancer treatment: from clinical practice to emerging chemical therapies. Expert Opinion on Pharmacotherapy 18:14, pages 1443-1455.
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Alice Bergamini, Simone Ferrero, Umberto Leone Roberti Maggiore, Carolina Scala, Francesca Pella, Valerio Gaetano Vellone, Micaela Petrone, Emanuela Rabaiotti, Raffaella Cioffi, Massimo Candiani & Giorgia Mangili. (2016) Folate receptor alpha antagonists in preclinical and early stage clinical development for the treatment of epithelial ovarian cancer. Expert Opinion on Investigational Drugs 25:12, pages 1405-1412.
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Articles from other publishers (10)

Yi He, Salvador Alejo, Prabhakar Pitta Venkata, Jessica D. Johnson, Ilanna Loeffel, Uday P. Pratap, Yi Zou, Zhao Lai, Rajeshwar R. Tekmal, Edward R. Kost & Gangadhara R. Sareddy. (2022) Therapeutic Targeting of Ovarian Cancer Stem Cells Using Estrogen Receptor Beta Agonist. International Journal of Molecular Sciences 23:13, pages 7159.
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Stephanie Lheureux, Charlie Gourley, Ignace Vergote & Amit M Oza. (2019) Epithelial ovarian cancer. The Lancet 393:10177, pages 1240-1253.
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Tzu-Pin Lu, Kuan-Ting Kuo, Ching-Hsuan Chen, Ming-Cheng Chang, Hsiu-Ping Lin, Yu-Hao Hu, Ying-Cheng Chiang, Wen-Fang Cheng & Chi-An Chen. (2019) Developing a Prognostic Gene Panel of Epithelial Ovarian Cancer Patients by a Machine Learning Model. Cancers 11:2, pages 270.
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Han-Wei Lin, Chi-Feng Fu, Ming-Cheng Chang, Tzu-Pin Lu, Hsiu-Ping Lin, Ying-Cheng Chiang, Chi-An Chen & Wen-Fang Cheng. (2018) CDH1 , DLEC1 and SFRP5 methylation panel as a prognostic marker for advanced epithelial ovarian cancer . Epigenomics 10:11, pages 1397-1413.
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Xin Wu, Junda Zhao, Yuanyuan Ruan, Li Sun, Congjian Xu & Hua Jiang. (2018) Sialyltransferase ST3GAL1 promotes cell migration, invasion, and TGF-β1-induced EMT and confers paclitaxel resistance in ovarian cancer. Cell Death & Disease 9:11.
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Sophia A. Shahin, Ruining Wang, Shirleen I. Simargi, Altagracia Contreras, Liliana Parra Echavarria, Louise Qu, Wei Wen, Thanh Dellinger, Juli Unternaehrer, Fuyuhiko Tamanoi, Jeffrey I. Zink & Carlotta A. Glackin. (2018) Hyaluronic acid conjugated nanoparticle delivery of siRNA against TWIST reduces tumor burden and enhances sensitivity to cisplatin in ovarian cancer. Nanomedicine: Nanotechnology, Biology and Medicine 14:4, pages 1381-1394.
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Giulia Pinton, Stefan Nilsson & Laura Moro. (2018) Targeting estrogen receptor beta (ERβ) for treatment of ovarian cancer: importance of KDM6B and SIRT1 for ERβ expression and functionality. Oncogenesis 7:2.
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Lili Zhao, Jun Li, Manli Liu, Hongrun Zhou, Hong Zou, Yutao Wei, Kunming Sun, Ganxiong Li, Shugang Li & Lijuan Pang. (2017) The clinicopathological parameters significance of CD133 and Nestin in epithelial ovarian cancer: a meta-analysis. Future Oncology 13:28, pages 2555-2570.
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Angela Musella, Laura Vertechy, Alessia Romito, Claudia Marchetti, Andrea Giannini, Valentina Sciuga, Carlotta Bracchi, Federica Tomao, Violante Di Donato, Francesca De Felice, Marco Monti, Ludovico Muzii & Pierluigi Benedetti Panici. (2017) Bevacizumab in Ovarian Cancer: State of the Art and Unanswered Questions. Chemotherapy 62:2, pages 111-120.
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Lu Huang, Ye Jin, Shujun Feng, Yuqing Zou, Sainan Xu, Shuang Qiu, Ling Li & Jianhua Zheng. (2016) Role of Wnt/β-catenin, Wnt/c-Jun N-terminal kinase and Wnt/Ca2+ pathways in cisplatin-induced chemoresistance in ovarian cancer. Experimental and Therapeutic Medicine 12:6, pages 3851-3858.
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