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Drug Evaluations

Trabectedin for the treatment of breast cancer

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Silvia Pegoraro, Gloria Ros, Michela Sgubin, Sara Petrosino, Alberto Zambelli, Riccardo Sgarra & Guidalberto Manfioletti. (2020) Targeting the intrinsically disordered architectural High Mobility Group A (HMGA) oncoproteins in breast cancer: learning from the past to design future strategies. Expert Opinion on Therapeutic Targets 24:10, pages 953-969.
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Simone Borgoni, Andrea Iannello, Santina Cutrupi, Paola Allavena, Maurizio D'Incalci, Francesco Novelli & Paola Cappello. (2018) Depletion of tumor-associated macrophages switches the epigenetic profile of pancreatic cancer infiltrating T cells and restores their anti-tumor phenotype. OncoImmunology 7:2.
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Adrián Povo-Retana, Marco Fariñas, Rodrigo Landauro-Vera, Marina Mojena, Carlota Alvarez-Lucena, Miguel A. Fernández-Moreno, Antonio Castrillo, Juan Vladimir de la Rosa Medina, Sergio Sánchez-García, Carles Foguet, Francesc Mas, Silvia Marin, Marta Cascante & Lisardo Boscá. (2023) Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: relevance for their anti-tumor activity. Frontiers in Immunology 14.
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Li Xiao, Qiao Wang & Hongling Peng. (2023) Tumor-associated macrophages: new insights on their metabolic regulation and their influence in cancer immunotherapy. Frontiers in Immunology 14.
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Weihong Huang, Zhong Li, Yanlei Kang, Xinghuo Ye & Wenming Feng. (2022) Drug Repositioning Based on the Enhanced Message Passing and Hypergraph Convolutional Networks. Biomolecules 12:11, pages 1666.
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Depeng Yang, Lijun Yang, Jialing Cai, Huaxin Li, Zheng Xing & Ying Hou. (2022) Phosphoinositide 3-kinase/Akt and its related signaling pathways in the regulation of tumor-associated macrophages polarization. Molecular and Cellular Biochemistry 477:10, pages 2469-2480.
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Rita De Sanctis, Flavia Jacobs, Chiara Benvenuti, Mariangela Gaudio, Raul Franceschini, Richard Tancredi, Paolo Pedrazzoli, Armando Santoro & Alberto Zambelli. (2022) From seaside to bedside: Current evidence and future perspectives in the treatment of breast cancer using marine compounds. Frontiers in Pharmacology 13.
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Francesco Pacifico, Stefano Mellone, Maurizio D'Incalci, Mariano Stornaiuolo, Antonio Leonardi & Elvira Crescenzi. (2022) Trabectedin suppresses escape from therapy-induced senescence in tumor cells by interfering with glutamine metabolism. Biochemical Pharmacology 202, pages 115159.
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Jiali Wang, Pengfei Wang, Zheng Zeng, Caiji Lin, Yiru Lin, Danli Cao, Wenqing Ma, Wenwen Xu, Qian Xiang, Lingjie Luo, Wenxue Wang, Yongwei Shi, Zixiang Gao, Yufan Zhao, Huidi Liu & Shu-Lin Liu. (2022) Trabectedin in Cancers: Mechanisms and Clinical Applications. Current Pharmaceutical Design 28:24, pages 1949-1965.
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Huakan Zhao, Lei Wu, Guifang Yan, Yu Chen, Mingyue Zhou, Yongzhong Wu & Yongsheng Li. (2021) Inflammation and tumor progression: signaling pathways and targeted intervention. Signal Transduction and Targeted Therapy 6:1.
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Yifan Tan, Min Wang, Yang Zhang, Shengyang Ge, Fan Zhong, Guowei Xia & Chuanyu Sun. (2021) Tumor-Associated Macrophages: A Potential Target for Cancer Therapy. Frontiers in Oncology 11.
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Nádia Ghinelli Amôr, Paulo Sérgio da Silva Santos & Ana Paula Campanelli. (2021) The Tumor Microenvironment in SCC: Mechanisms and Therapeutic Opportunities. Frontiers in Cell and Developmental Biology 9.
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Nan Cheng, Xuexia Bai, Yuxin Shu, Owais Ahmad & Pingping Shen. (2021) Targeting tumor-associated macrophages as an antitumor strategy. Biochemical Pharmacology 183, pages 114354.
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Soumaya Souid, Dorra Aissaoui, Najet Srairi-Abid & Khadija Essafi-Benkhadir. (2020) Trabectedin (Yondelis®) as a Therapeutic Option in Gynecological Cancers: A Focus on its Mechanisms of Action, Clinical Activity and Genomic Predictors of Drug Response. Current Drug Targets 21:10, pages 996-1007.
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David S. Moura, Paloma Sanchez-Bustos, Antonio Fernandez-Serra, María Lopez-Alvarez, José L. Mondaza-Hernandez, Elena Blanco-Alcaina, Angela Gavilan-Naranjo, Paula Martinez-Delgado, Serena Lacerenza, Paloma Santos-Fernandez, Irene Carrasco-Garcia, Samuel Hidalgo-Rios, Antonio Gutierrez, Rafael Ramos, Nadia Hindi, Miguel Taron, Jose Antonio Lopez-Guerrero & Javier Martin-Broto. (2020) CUL4A, ERCC5, and ERCC1 as Predictive Factors for Trabectedin Efficacy in Advanced Soft Tissue Sarcomas (STS): A Spanish Group for Sarcoma Research (GEIS) Study. Cancers 12:5, pages 1128.
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Jihyun Kim, Doyeong Yu, Youngmee Kwon, Keun Seok Lee, Sung Hoon Sim, Sun-Young Kong, Eun Sook Lee, In Hae Park & Charny Park. (2020) Genomic Characteristics of Triple-Negative Breast Cancer Nominate Molecular Subtypes That Predict Chemotherapy Response. Molecular Cancer Research 18:2, pages 253-263.
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C. Rubio, E. Munera-Maravilla, I. Lodewijk, C. Suarez-Cabrera, V. Karaivanova, R. Ruiz-Palomares, J. M. Paramio & M. Dueñas. (2018) Macrophage polarization as a novel weapon in conditioning tumor microenvironment for bladder cancer: can we turn demons into gods?. Clinical and Translational Oncology 21:4, pages 391-403.
Crossref
Mauro Provinciali, Elisa Pierpaoli, Marco Malavolta, Alessia Donnini, Arianna Smorlesi & Cristina Gatti. 2019. Handbook of Immunosenescence. Handbook of Immunosenescence 2115 2145 .
Simona Camorani, Laura Cerchia, Monica Fedele, Eugenio Erba, Maurizio D’Incalci & Elvira Crescenzi. (2018) Trabectedin modulates the senescence-associated secretory phenotype and promotes cell death in senescent tumor cells by targeting NF-κB. Oncotarget 9:28, pages 19929-19944.
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Paola Cappello, Claudia Curcio, Giorgia Mandili, Cecilia Roux, Sara Bulfamante & Francesco Novelli. (2018) Next Generation Immunotherapy for Pancreatic Cancer: DNA Vaccination is Seeking New Combo Partners. Cancers 10:2, pages 51.
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Meher Majety, Valeria Runza, Christian Lehmann, Sabine Hoves & Carola H. Ries. (2017) A drug development perspective on targeting tumor‐associated myeloid cells. The FEBS Journal 285:4, pages 763-776.
Crossref
Mauro Provinciali, Elisa Pierpaoli, Marco Malavolta, Alessia Donnini, Arianna Smorlesi & Cristina Gatti. 2017. Handbook of Immunosenescence. Handbook of Immunosenescence 1 31 .
Kei Kawaguchi, Kentaro Igarashi, Takashi Murakami, Tasuku Kiyuna, Thinzar M. Lwin, Ho Kyoung Hwang, Jonathan C. Delong, Bryan M. Clary, Michael Bouvet, Michiaki Unno & Robert M. Hoffman. (2017) MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX). Oncotarget 8:29, pages 47490-47496.
Crossref
Géraldine Genard, Stéphane Lucas & Carine Michiels. (2017) Reprogramming of Tumor-Associated Macrophages with Anticancer Therapies: Radiotherapy versus Chemo- and Immunotherapies. Frontiers in Immunology 8.
Crossref
Karin Binnemars-Postma, Gert Storm & Jai Prakash. (2017) Nanomedicine Strategies to Target Tumor-Associated Macrophages. International Journal of Molecular Sciences 18:5, pages 979.
Crossref
Xin Miao, Gilbert Koch, Sihem Ait-Oudhia, Robert M. Straubinger & William J. Jusko. (2016) Pharmacodynamic Modeling of Cell Cycle Effects for Gemcitabine and Trabectedin Combinations in Pancreatic Cancer Cells. Frontiers in Pharmacology 7.
Crossref
Bradley J. Monk, Domenica Lorusso, Antoine Italiano, Stan B. Kaye, Miguel Aracil, Adnan Tanovi?Maurizio D?Incalci. (2016) Trabectedin as a chemotherapy option for patients with BRCA deficiency. Cancer Treatment Reviews 50, pages 175-182.
Crossref
Joanne L. Blum, Anthony Gonçalves, Noa Efrat, Marc Debled, Pierfranco Conte, Paul D. Richards, Donald Richards, Pilar Lardelli, Antonio Nieto, Martin Cullell-Young & Suzette Delaloge. (2016) A phase II trial of trabectedin in triple-negative and HER2-overexpressing metastatic breast cancer. Breast Cancer Research and Treatment 155:2, pages 295-302.
Crossref

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