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Review

N-methyl-D-aspartate antagonists for stroke and head trauma

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Pages 389-397 | Published online: 23 Feb 2005

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John A McCauley. (2005) NR2B subtype-selective NMDA receptor antagonists: 2001 – 2004. Expert Opinion on Therapeutic Patents 15:4, pages 389-407.
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Jinyang Hong, Eva Lee, Joi C. Carter, Jeff A. Masse & Darlene A. Oksanen. (2004) Antioxidant‐Accelerated Oxidative Degradation: A Case Study of Transition Metal Ion Catalyzed Oxidation in Formulation. Pharmaceutical Development and Technology 9:2, pages 171-179.
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Trevor W Stone. (2001) Kynurenic acid antagonists and kynurenine pathway inhibitors. Expert Opinion on Investigational Drugs 10:4, pages 633-645.
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Maria Elvira Tranquillini & Angelo Reggiani. (1999) Glycine-site antagonists and stroke. Expert Opinion on Investigational Drugs 8:11, pages 1837-1848.
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Paul L Wood. (1998) NMDA antagonists for stroke and head trauma: current status. Expert Opinion on Investigational Drugs 7:9, pages 1505-1508.
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Articles from other publishers (20)

Mohammadian Maryam & Bahaoddini Aminollah. (2023) IC87201, a PSD-95/nNOS Inhibitor, Ameliorates Heart Rate Variability in the Rat Model of Middle Cerebral Artery Occlusion. Insights in Biology and Medicine 7:1, pages 001-006.
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Chuan Qin, Sheng Yang, Yun-Hui Chu, Hang Zhang, Xiao-Wei Pang, Lian Chen, Luo-Qi Zhou, Man Chen, Dai-Shi Tian & Wei Wang. (2022) Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions. Signal Transduction and Targeted Therapy 7:1.
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Yu Diao, Weijie Yan, Wei Sun, Yanlin Luo, Junfa Li & Yanling Yin. (2018) The dual role of KCNQ/M channels upon OGD or OGD/R insults in cultured cortical neurons of mice: Timing is crucial in targeting M‐channels against ischemic injur ies . Journal of Cellular Physiology 234:8, pages 12714-12726.
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Qiu Jing Wu & Michael Tymianski. (2018) Targeting NMDA receptors in stroke: new hope in neuroprotection. Molecular Brain 11:1.
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Cristobal de los Rios, Maria F. Cano-Abad, Mercedes Villarroya & Manuela G. López. (2017) Chromaffin cells as a model to evaluate mechanisms of cell death and neuroprotective compounds. Pflügers Archiv - European Journal of Physiology 470:1, pages 187-198.
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Jessica A. Panzer, Amy J. Gleichman & David R. Lynch. (2014) Glutamatergic autoencephalitides: an emerging field. Journal of Neural Transmission 121:8, pages 957-968.
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Sandra M. Vetiska & Michael Tymianski. 2014. Handbook of Neurotoxicity. Handbook of Neurotoxicity 1381 1402 .
Manuela Mellone & Fabrizio Gardoni. (2013) Modulation of NMDA receptor at the synapse: Promising therapeutic interventions in disorders of the nervous system. European Journal of Pharmacology 719:1-3, pages 75-83.
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Robert Meller. 2013. Innate Tolerance in the CNS. Innate Tolerance in the CNS 339 361 .
Andrew J Gauden, Veronica Pitt & Russell L Gruen. (2012) Excitatory amino acid inhibitors for traumatic brain injury. Cochrane Database of Systematic Reviews.
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Aarti Sarwal, Muhammad Shazam Hussain & Ashfaq Shuaib. 2012. Translational Stroke Research. Translational Stroke Research 79 97 .
Ted Weita Lai, Woei-Cherng Shyu & Yu Tian Wang. (2011) Stroke intervention pathways: NMDA receptors and beyond. Trends in Molecular Medicine 17:5, pages 266-275.
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Robert Meller & Roger P. Simon. 2008. Structural And Functional Organization Of The Synapse. Structural And Functional Organization Of The Synapse 731 758 .
Carmen Villmann & Cord-Michael Becker. (2007) On the Hypes and Falls in Neuroprotection: Targeting the NMDA Receptor. The Neuroscientist 13:6, pages 594-615.
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Chandra Prakash, Donghui Cui, Michael J. Potchoiba & Todd Butler. (2007) Metabolism, Distribution and Excretion of a Selective N -Methyl-d-Aspartate Receptor Antagonist, Traxoprodil, in Rats and Dogs . Drug Metabolism and Disposition 35:8, pages 1350-1364.
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Angela Angusti, Elisa Durini, Silvia Vertuani, Alessandro Dalpiaz, A. Ruffo, Romano Di Fabio, Daniele Donati, Giorgio Pentassuglia, Giovanni Vitulli, Robert J. Barnaby & Stefano Manfredini. (2005) Synthesis and biological evaluation of pro-drugs of GW196771, a potent glycine antagonist acting at the NMDA receptor. Il Farmaco 60:5, pages 393-397.
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Trevor W Stone. (2001) Kynurenines in the CNS: from endogenous obscurity to therapeutic importance. Progress in Neurobiology 64:2, pages 185-218.
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Deborah A Dawson, Graham Wadsworth & Alan M Palmer. (2001) A comparative assessment of the efficacy and side-effect liability of neuroprotective compounds in experimental stroke. Brain Research 892:2, pages 344-350.
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Alain Boireau, Carole Monterrat, Françoise Bordier, Mireille Meunier & Assunta Imperato. (2000) Effects of RPR 118723, a novel antagonist at the glycine site of the NMDA receptor, in vitro. European Journal of Pharmacology 401:2, pages 131-135.
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Trevor W Stone. (2000) Inhibitors of the kynurenine pathway. European Journal of Medicinal Chemistry 35:2, pages 179-186.
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