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Expert Opinion on Investigational Drugs Volume 7, 1998 - Issue 1
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Drug Evaluation

Modafinil: a novel stimulant for the treatment of narcolepsy

Thomas E Scammell Sleep Disorders Program, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave., Boston, MA 02215, USA.
&
Jean Matheson Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave., Boston, MA 02215, USA.
Pages 99-112 | Published online: 23 Feb 2005

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Ramalingam Vetrivelan, Clifford B Saper & Patrick M Fuller. (2014) Armodafinil-induced wakefulness in animals with ventrolateral preoptic lesions. Nature and Science of Sleep 6, pages 57-63.
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Articles from other publishers (14)

Keri-Ann Buchanan-Peart & Cynthia Levy. (2022) Novel Therapies in Primary Biliary Cholangitis. Clinics in Liver Disease 26:4, pages 747-764.
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Michael J. Thorpy & Richard K. Bogan. (2020) Update on the pharmacologic management of narcolepsy: mechanisms of action and clinical implications. Sleep Medicine 68, pages 97-109.
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Amberkar Mohanbabu Vittalrao, Abhishek ChakrabortiMeena Kumari KNandit BanawalikarKiran Kumar N. (2019) Evaluation of Vigilance Promoting Drugs Modafinil and Caffeine on Cognition Enhancing Activities in Wistar Albino Rats-A Comparative Study. Biomedical & Pharmacology Journal 12:3, pages 1463-1470.
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Xiao Yu, Ying Ma, Edward C Harding, Raquel Yustos, Alexei L Vyssotski, Nicholas P Franks & William Wisden. (2019) Genetic lesioning of histamine neurons increases sleep–wake fragmentation and reveals their contribution to modafinil-induced wakefulness. Sleep 42:5.
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Michel Billiard & Roger Broughton. (2018) Modafinil: its discovery, the early European and North American experience in the treatment of narcolepsy and idiopathic hypersomnia, and its subsequent use in other medical conditions. Sleep Medicine.
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Michal Gajewski & Gerald Weinhouse. (2015) The Use of Modafinil in the Intensive Care Unit. Journal of Intensive Care Medicine 31:2, pages 142-145.
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A. Claret, S. Bioulac, M. Bouvard & P. Philip. (2014) Trouble déficit de l’attention/hyperactivité chez l’adulte et troubles du sommeil : revue de la littérature. Médecine du Sommeil 11:4, pages 165-181.
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Christian R. Burgess & Thomas E. Scammell. (2012) Narcolepsy: Neural Mechanisms of Sleepiness and Cataplexy. The Journal of Neuroscience 32:36, pages 12305-12311.
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Deirdre A. Conroy & Kirk J. Brower. 2011. Sleep Disorders. Sleep Disorders 587 612 .
Christian R. Burgess, Gavin Tse, Lauren Gillis & John H. Peever. (2010) Dopaminergic Regulation of Sleep and Cataplexy in a Murine Model of Narcolepsy. Sleep 33:10, pages 1295-1304.
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Scott Grady, Daniel Aeschbach, Kenneth P Wright & Charles A Czeisler. (2010) Effect of Modafinil on Impairments in Neurobehavioral Performance and Learning Associated with Extended Wakefulness and Circadian Misalignment. Neuropsychopharmacology 35:9, pages 1910-1920.
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Marian Tsanov, Declan G. Lyons, Sally Barlow, Rodrigo E. González Reyes & Shane M. O’Mara. (2010) The psychostimulant modafinil facilitates water maze performance and augments synaptic potentiation in dentate gyrus. Neuropharmacology 59:1-2, pages 9-19.
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E. GALVIN, H. BOESJES, J. HOL, J. F. UBBEN, J. KLEIN & S. J. C. VERBRUGGE. (2010) Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills. Acta Anaesthesiologica Scandinavica 54:2, pages 154-161.
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S. Ian Gan, Mariana de Jongh & Marshall M. Kaplan. (2008) Modafinil in the Treatment of Debilitating Fatigue in Primary Biliary Cirrhosis: A Clinical Experience. Digestive Diseases and Sciences 54:10, pages 2242-2246.
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