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Expert Opinion on Investigational Drugs Volume 9, 2000 - Issue 5
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Drug Evaluation

Bivalirudin: a new generation antithrombotic drug

Roberto Scatena Istituto Chimica e Chimica Clinica, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy. [email protected]
Pages 1119-1127 | Published online: 24 Feb 2005

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M. van Gameren, M. E. Lemmert, J. M. Wilschut, J. Daemen, P. P. T. De Jaegere, F. Zijlstra, N. M. D. A. Van Mieghem & R. Diletti. (2018) An update on the use of anticoagulant therapy in ST-segment elevation myocardial infarction. Expert Opinion on Pharmacotherapy 19:13, pages 1441-1450.
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Torsten Steinmetzer, Jörg Hauptmann & Jörg Stürzebecher. (2001) Advances in the development of thrombin inhibitors. Expert Opinion on Investigational Drugs 10:5, pages 845-864.
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Articles from other publishers (18)

Chen Junren, Xie Xiaofang, Zhang Huiqiong, Li Gangmin, Yin Yanpeng, Cao Xiaoyu, Gao Yuqing, Li Yanan, Zhang Yue, Peng Fu & Peng Cheng. (2021) Pharmacological Activities and Mechanisms of Hirudin and Its Derivatives - A Review. Frontiers in Pharmacology 12.
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Hanxiong Liu, Shuzhen Cheng, Zhenyu Wang & Ming Du. (2020) Evaluation and Improvement of in vitro Detection Methods of Thrombin Inhibitor Activity . eFood 1:5, pages 377-379.
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Takahiro Nonaka, Noriko Tsurui, Teruhisa Mannen, Yoshimi Kikuchi & Kentaro Shiraki. (2018) A new pH-responsive peptide tag for protein purification. Protein Expression and Purification 146, pages 91-96.
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J. A. Hutchinson, S. Burholt & I. W. Hamley. (2017) Peptide hormones and lipopeptides: from self-assembly to therapeutic applications. Journal of Peptide Science 23:2, pages 82-94.
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Maximilian H. M. Hatz, Reiner Leidl, Nichola A. Yates & Björn Stollenwerk. (2014) A Systematic Review of the Quality of Economic Models Comparing Thrombosis Inhibitors in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. PharmacoEconomics 32:4, pages 377-393.
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Elena I. Sinauridze, Mikhail A. Panteleev & Fazoil I. Ataullakhanov. (2012) Anticoagulant therapy. Blood Coagulation & Fibrinolysis 23:6, pages 482-493.
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Songbin Ben, Bin Liu, Xiujun Deng, Lei Bai & Changlan Chen. (2009) Expression and Affinity Purification of Small Molecule Functional Peptide of Hirudin in E. coli. Expression and Affinity Purification of Small Molecule Functional Peptide of Hirudin in E. coli.
Said Charef, Emmanuel Petit, Denis Barritault, José Courty & Jean‐Pierre Caruelle. (2007) Effects on coagulation of a synthetic heparan mimetic given intraperitoneally or orally. Journal of Biomedical Materials Research Part A 83A:4, pages 1024-1031.
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Theodore E. Warkentin & Andreas GreinacherJohn R. Bartholomew. 2007. Heparin-Induced Thrombocytopenia. Heparin-Induced Thrombocytopenia 409 440 .
Edith A Nutescu & Ann K Wittkowsky. (2004) Direct Thrombin Inhibitors for Anticoagulation. Annals of Pharmacotherapy 38:1, pages 99-109.
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Stig L Boström, Göran F.H Hansson, Troy C Sarich & Michael Wolzt. (2004) The inhibitory effect of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, compared with enoxaparin and r-hirudin on ex vivo thrombin generation in human plasma. Thrombosis Research 113:1, pages 85-91.
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Rahat Kumar, Narinder Singh, Kartar Singh, Atul Kalhan & K. K. Prasad. (2004) Recent insights on biochemical and molecular basis for developing antihaemostatic agents: A review. Indian Journal of Clinical Biochemistry 19:1, pages 122-128.
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Jack Hirsh. (2003) Current anticoagulant therapy—unmet clinical needs. Thrombosis Research 109, pages S1-S8.
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Donald J. AbrahamGregory S. Bisacchi. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 283 338 .
Barbara S. Wiggins, Sarah Spinler, Ann K. Wittkowsky & Kathleen A. Stringer. (2012) Bivalirudin: A Direct Thrombin Inhibitor for Percutaneous Transluminal Coronary Angioplasty. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 22:8, pages 1007-1018.
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Perumal Thiagarajan. (2002) New Targets for Antithrombotic Drugs. American Journal of Cardiovascular Drugs 2:4, pages 227-235.
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Christopher I. Carswell & Greg L. Plosker. (2002) Bivalirudin. Drugs 62:5, pages 841-870.
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Bernard Gaudilliere, Patrick Bernardelli & Patrick Berna. 2001. 293 318 .

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