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Expert Opinion on Pharmacotherapy Volume 10, 2009 - Issue 15
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Editorial

Metformin: diamonds are forever

N Papanas Democritus University of Thrace, Second Department of Internal Medicine, Outpatient Clinic of Obesity, Diabetes and Metabolism, Alexandroupolis, Greece +30 6977 544337; +30 25510 74723; [email protected]
,
E Maltezos Democritus University of Thrace, Second Department of Internal Medicine, Outpatient Clinic of Obesity, Diabetes and Metabolism, Alexandroupolis, Greece +30 6977 544337; +30 25510 74723; [email protected]
&
DP Mikhailidis University College London, Royal Free Campus, University College London Medical School, Department of Clinical Biochemistry (Vascular Disease Prevention Clinics), London, UK
Pages 2395-2397 | Published online: 13 Aug 2009

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Natascha Schweighofer, Bernd Genser, Winfried Maerz, Marcus E Kleber, Olivia Trummer, Thomas R Pieber & Barbara Obermayer-Pietsch. (2020) Intronic Variants in OCT1 are Associated with All-Cause and Cardiovascular Mortality in Metformin Users with Type 2 Diabetes. Diabetes, Metabolic Syndrome and Obesity 13, pages 2069-2080.
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Jingbo Hu, Ping Zou, Shuo Zhang, Minzhi Zhou & Xueying Tan. (2016) Empagliflozin/metformin fixed-dose combination: a review in patients with type 2 diabetes. Expert Opinion on Pharmacotherapy 17:18, pages 2471-2477.
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Nikolaos Papanas, Efstratios Maltezos & Dimitri P Mikhailidis. (2012) Metformin and heart failure: never say never again. Expert Opinion on Pharmacotherapy 13:1, pages 1-8.
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Nikolaos Papanas, Efstratios Maltezos & Dimitri P Mikhailidis. (2010) Metformin and cancer: licence to heal?. Expert Opinion on Investigational Drugs 19:8, pages 913-917.
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Articles from other publishers (21)

Ravisinh Solanki, Pooja Wadhwana, Ravi Patel, Bhavinkumar Gayakvad, Charmy Kothari & Chhaganbhai Patel. (2023) Analytical Method Capable of Quantifying Eight Nitrosamine Impurities from Five Different Commercially Available Metformin Formulations with Glipizide, Glibenclamide, Gliclazide, Evogliptin, and Glimepiride by Ultra High Performance Liquid Chromatography Tripple Quadrupole Mass Spectrometry. Journal of Pharmaceutical Sciences 112:5, pages 1268-1276.
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Kalliopi Pafili & Michael Roden. (2021) Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans. Molecular Metabolism 50, pages 101122.
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A. Kavyasree, P. Geetha & P. Shanmugasundaram. (2021) A Review: Comparison of Efficacy of Liraglutide Versus Sitagliptin add-on-to Metformin in Type 2 Diabetes Mellitus patients. Research Journal of Pharmacy and Technology, pages 2291-2295.
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Stella Papachristou & Nikolaos Papanas. (2021) Reduction of Depression in Diabetes: A New Pleiotropic Action of Metformin?. Diabetes Therapy 12:4, pages 965-968.
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Niki Katsiki, Ele Ferrannini & Christos Mantzoros. (2020) New American Diabetes Association (ADA)/European Association for the Study of Diabetes (EASD) guidelines for the pharmacotherapy of type 2 diabetes: Placing them into a practicing physician's perspective. Metabolism 107, pages 154218.
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Morris KarmazynXiaohong Tracey Gan. (2019) Ginseng for the treatment of diabetes and diabetes-related cardiovascular complications: a discussion of the evidence. Canadian Journal of Physiology and Pharmacology 97:4, pages 265-276.
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Nagaraja M Phani, Manik Vohra, Ananth Kakar, Prabha Adhikari, Shivashankara K Nagri, Sydney C D'Souza, Shashikiran Umakanth, Kapaettu Satyamoorthy & Padmalatha S Rai. (2018) Implication of critical pharmacokinetic gene variants on therapeutic response to metformin in Type 2 diabetes. Pharmacogenomics 19:11, pages 905-911.
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Lucio Dell'Atti & Andrea B. Galosi. (2018) The impact of metformin use on the risk of prostate cancer after prostate biopsy in patients with high grade intraepithelial neoplasia. International braz j urol 44:1, pages 69-74.
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Mingxing Li, Yi Yang, Deqi Jiang, Miaofa Ying, Yong Wang & Rui Zhao. (2017) Efficacy and safety of liraglutide versus sitagliptin both in combination with metformin in patients with type 2 diabetes. Medicine 96:39, pages e8161.
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Yoon Suk Jung, Chan Hyuk Park, Chang Soo Eun, Dong Il Park & Dong Soo Han. (2017) Metformin use and the risk of colorectal adenoma: A systematic review and meta-analysis. Journal of Gastroenterology and Hepatology 32:5, pages 957-965.
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T. Rokkas & P. Portincasa. (2016) Colon neoplasia in patients with type 2 diabetes on metformin: A meta-analysis. European Journal of Internal Medicine 33, pages 60-66.
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Gurusamy Umamaheswaran, Ramakrishnan Geethakumari Praveen, Solai Elango Damodaran, Ashok Kumar Das & Chandrasekaran Adithan. (2014) Influence of SLC22A1 rs622342 genetic polymorphism on metformin response in South Indian type 2 diabetes mellitus patients. Clinical and Experimental Medicine 15:4, pages 511-517.
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Hongliang Yu, Li Yin, Xuesong Jiang, Xiujin Sun, Jing Wu, Hao Tian, Xianshu Gao & Xia He. (2014) Effect of Metformin on Cancer Risk and Treatment Outcome of Prostate Cancer: A Meta-Analysis of Epidemiological Observational Studies. PLoS ONE 9:12, pages e116327.
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Maria-Agata Miselli, Edoardo Dalla Nora, Angelina Passaro, Franco Tomasi & Giovanni Zuliani. (2014) Plasma triglycerides predict ten-years all-cause mortality in outpatients with type 2 diabetes mellitus: a longitudinal observational study. Cardiovascular Diabetology 13:1.
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Raylene A Reimer, Gary J Grover, Lee Koetzner, Roland J Gahler, Michael R Lyon & Simon Wood. (2014) Combining sitagliptin/metformin with a functional fiber delays diabetes progression in Zucker rats. Journal of Endocrinology 220:3, pages 361-373.
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Monica Franciosi, Giuseppe Lucisano, Emanuela Lapice, Giovanni F. M. Strippoli, Fabio Pellegrini & Antonio Nicolucci. (2013) Metformin Therapy and Risk of Cancer in Patients with Type 2 Diabetes: Systematic Review. PLoS ONE 8:8, pages e71583.
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Kim A. Pyra, Dolan C. Saha & Raylene A. Reimer. (2012) Prebiotic Fiber Increases Hepatic Acetyl CoA Carboxylase Phosphorylation and Suppresses Glucose-Dependent Insulinotropic Polypeptide Secretion More Effectively When Used with Metformin in Obese Rats,. The Journal of Nutrition 142:2, pages 213-220.
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Evanthia Gouveri, Nikolaos Papanas & Efstratios Maltezos. (2011) The female breast and diabetes. The Breast 20:3, pages 205-211.
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Kosmas I. ParaskevasAlkistis Pantopoulou, Ioannis S. Vlachos, George Agrogiannis, Dimitrios G. Iliopoulos, Gabriel Karatzas, Dimitrios Tzivras, Dimitri P. Mikhailidis & Despina N. Perrea. (2011) Comparison of Fibrate, Ezetimibe, Low- and High-Dose Statin Therapy for the Dyslipidemia of the Metabolic Syndrome in a Mouse Model. Angiology 62:2, pages 144-154.
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Cheng-Xi Zhang, Si-Nian Pan, Rong-Sen Meng, Chao-Quan Peng, Zhao-Jun Xiong, Bao-Lin Chen, Guang-Qin Chen, Feng-Juan Yao, Yi-Li Chen, Yue-Dong Ma & Yu-Gang Dong. (2011) Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats. Clinical and Experimental Pharmacology and Physiology 38:1, pages 55-62.
Crossref
Andrea DeCensi, Matteo Puntoni, Pamela Goodwin, Massimiliano Cazzaniga, Alessandra Gennari, Bernardo Bonanni & Sara Gandini. (2010) Metformin and Cancer Risk in Diabetic Patients: A Systematic Review and Meta-analysis. Cancer Prevention Research 3:11, pages 1451-1461.
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