Quetiapine XR efficacy and tolerability as monotherapy and as adjunctive treatment to conventional antidepressants in the acute and maintenance treatment of major depressive disorder: a review of registration trials

Roger S McIntyre University of Toronto, Department of Psychiatry, Toronto, ON, Canada; University of Toronto, Department of Pharmacology, Toronto, ON, Canada; University Health Network, Toronto Western Hospital, Mood Disorders Psychopharmacology Unit, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada +1 416 603 5279; +1 416 603 5368; [email protected]; University of Toronto, Institute of Medical Science, Toronto, ON, Canada

, MD FRCPC,

David J Muzina Cleveland Clinic Psychiatry & PsychologyTreatment & Research, 9500 Euclid Avenue, P57 Cleveland Clinic,Cleveland, OH 44195, USA [email protected]

Amanda Adams University Health Network, Toronto Western Hospital, Mood Disorders Psychopharmacology Unit, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada +1 416 603 5279; +1 416 603 5368; [email protected]

Maria Teresa C Lourenco University Health Network, Toronto Western Hospital, Mood Disorders Psychopharmacology Unit, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada +1 416 603 5279; +1 416 603 5368; [email protected]

Candy WY Law University Health Network, Toronto Western Hospital, Mood Disorders Psychopharmacology Unit, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada +1 416 603 5279; +1 416 603 5368; [email protected]

Joanna K Soczynska University Health Network, Toronto Western Hospital, Mood Disorders Psychopharmacology Unit, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada +1 416 603 5279; +1 416 603 5368; [email protected]; University of Toronto, Institute of Medical Science, Toronto, ON, Canada

Hanna O Woldeyohannes University Health Network, Toronto Western Hospital, Mood Disorders Psychopharmacology Unit, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada +1 416 603 5279; +1 416 603 5368; [email protected]

Jay Nathanson University Health Network, Toronto Western Hospital, Mood Disorders Psychopharmacology Unit, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada +1 416 603 5279; +1 416 603 5368; [email protected]

Sidney H Kennedy University Health Network, Toronto Western Hospital, Mood Disorders Psychopharmacology Unit, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada +1 416 603 5279; +1 416 603 5368; [email protected]; University of Toronto, Institute of Medical Science, Toronto, ON, Canada

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Quetiapine XR efficacy and tolerability as monotherapy and as adjunctive treatment to conventional antidepressants in the acute and maintenance treatment of major depressive disorder: a review of registration trials

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Quetiapine XR efficacy and tolerability as monotherapy and as adjunctive treatment to conventional antidepressants in the acute and maintenance treatment of major depressive disorder: a review of registration trials

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