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Paola Rogliani, Luigino Calzetta, Mario Cazzola & Maria Gabriella Matera. (2016) Drug safety evaluation of roflumilast for the treatment of COPD: a meta-analysis. Expert Opinion on Drug Safety 15:8, pages 1133-1146.
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Stephen I Rennard, Fernando J Martinez, Klaus F Rabe, Sanjay Sethi, Emilio Pizzichini, Andrew McIvor, Shahid Siddiqui, Antonio Anzueto & Haiyuan Zhu. (2016) Effects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting β2-agonist fixed-dose combination: RE2SPOND rationale and study design. International Journal of Chronic Obstructive Pulmonary Disease 11, pages 1921-1928.
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Donald P Tashkin. (2010) Impact of tiotropium on the course of moderate-to-very severe chronic obstructive pulmonary disease: the UPLIFT® trial. Expert Review of Respiratory Medicine 4:3, pages 279-289.
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Xinjie Zhu, Jun Wei, Chenxian Hu, Qitao Xiao, Lvtao Cai, Hao Wang, Yuanyuan Xie & Rong Sheng. (2022)
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Guo-Kai Liu, Wen-Bing Qin, Xin Li, Li-Ting Lin & Henry N. C. Wong. (2019)
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Guo-Kai Liu, Xin Li, Wen-Bing Qin, Wei-Feng Lin, Li-Ting Lin, Jia-Yi Chen & Jian-Jian Liu. (2019) Selective O-difluoromethylation of 1,3-diones using S-(difluoromethyl) sulfonium salt. Chinese Chemical Letters 30:8, pages 1515-1518.
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Guo-Kai Liu, Xin Li, Wen-Bing Qin, Xiao-Shui Peng, Henry N. C. Wong, Linxing Zhang & Xinhao Zhang. (2019)
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Taiji Goto, Akiko Shiina, Takeshi Murata, Masato Tomii, Takanori Yamazaki, Ken-ichi Yoshida, Toshiharu Yoshino, Osamu Suzuki, Yoshitaka Sogawa, Kiyoshi Mizukami, Nana Takagi, Tomomi Yoshitomi, Maki Etori, Hiroshi Tsuchida, Tsuyoshi Mikkaichi, Naoki Nakao, Mizuki Takahashi, Hisashi Takahashi & Shigeki Sasaki. (2014) Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors. Bioorganic & Medicinal Chemistry Letters 24:3, pages 893-899.
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Taiji Goto, Akiko Shiina, Toshiharu Yoshino, Kiyoshi Mizukami, Kazuki Hirahara, Osamu Suzuki, Yoshitaka Sogawa, Tomoko Takahashi, Tsuyoshi Mikkaichi, Naoki Nakao, Mizuki Takahashi, Masashi Hasegawa & Shigeki Sasaki. (2013) Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors. Bioorganic & Medicinal Chemistry 21:22, pages 7025-7037.
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Timothy E. Albertson, Michael Schivo, Amir A. Zeki, Samuel Louie, Mark E. Sutter, Mark Avdalovic & Andrew L. Chan. (2013) The Pharmacological Approach to the Elderly COPD Patient. Drugs & Aging 30:7, pages 479-502.
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Taiji Goto, Akiko Shiina, Toshiharu Yoshino, Kiyoshi Mizukami, Kazuki Hirahara, Osamu Suzuki, Yoshitaka Sogawa, Tomoko Takahashi, Tsuyoshi Mikkaichi, Naoki Nakao, Mizuki Takahashi, Masashi Hasegawa & Shigeki Sasaki. (2013) Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors. Bioorganic & Medicinal Chemistry Letters 23:11, pages 3325-3328.
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Mario Cazzola, Clive P. Page, Luigino Calzetta & M. Gabriella Matera. (2012) Pharmacology and Therapeutics of Bronchodilators. Pharmacological Reviews 64:3, pages 450-504.
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Noah P. Zimmerman, Suresh N. Kumar, Jerrold R. Turner & Michael B. Dwinell. (2012) Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and RhoA*. Inflammatory Bowel Diseases 18:6, pages 1081-1091.
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Nikola Marjanović, Martina Bosnar, Francesca Michielin, David R. Willé, Tatjana Anić-Milić, Ognjen Čulić, Sanja Popović-Grle, Mile Bogdan, Michael J. Parnham & Vesna Eraković Haber. (2011) Macrolide antibiotics broadly and distinctively inhibit cytokine and chemokine production by COPD sputum cells in vitro. Pharmacological Research 63:5, pages 389-397.
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D Peter, R Göggel, F Colbatzky & P Nickolaus. (2010) Inhibition of cyclooxygenase‐2 prevents adverse effects induced by phosphodiesterase type 4 inhibitors in rats. British Journal of Pharmacology 162:2, pages 415-427.
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Mario Cazzola. (2010) The divergent opinions of regulatory authorities on roflumilast are puzzling but we need new drugs for treating chronic obstructive pulmonary disease. Therapeutic Advances in Respiratory Disease 4:4, pages 195-198.
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