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Drug Evaluations

Role of ribavirin in HCV treatment response: now and in the future

, MD MPH & , PharmD
Pages 673-683 | Published online: 17 Feb 2010

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Y.S. Li, J.J. Zhang, L.Q. Mei & C.X. Tan. (2012) An Improved Procedure for the Preparation of Ribavirin. Organic Preparations and Procedures International 44:4, pages 387-391.
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Towseef Akram, Irfan Gul, Mahrukh Parveez Zia, Amreena Hassan, Amina Khatun, Riaz Ahmad Shah, Syed Mudasir Ahmad, Nazir Ahmad Ganai, Naveed Anjum Chikan, Won-Il Kim & Nadeem Shabir. (2023) Ribavirin inhibits the replication of infectious bursal disease virus predominantly through depletion of cellular guanosine pool. Frontiers in Veterinary Science 10.
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Lisa Sandmann & Heiner Wedemeyer. (2022) Interferon‐based treatment of chronic hepatitis D. Liver International.
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K.S. Abdelkawy, S.M. El-Haggar, D.H. Ziada, N.F. Ebaid, M.A. El-Magd & F.A. Elbarbry. (2020) The effect of genetic variations on ribavirin pharmacokinetics and treatment response in HCV-4 Egyptian patients receiving sofosbuvir/daclatasvir and ribavirin. Biomedicine & Pharmacotherapy 121, pages 109657.
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Karina Gonzalez-Aldaco, Arturo Panduro, João R. Rebello Pinho, Erika Martinez-Lopez, Ketti Gleyzer, Nora A. Fierro & Sonia Roman. (2017) High Prevalence of ITPA Alleles Associated with Ribavirin-Induced Hemolytic Anemia Among Mexican Population. Annals of Hepatology 16:2, pages 221-229.
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Dorta Guridi Zaily, Castellanos Fernandez Marlen, Dueñas-Carrera Santiago, Martínez Donato Gillian, Valenzuela Silva Carmen, Cinza Estevez Zurina, Arús Soler Enrique R.Alvarez-Lajonchere Liz, González Fabián Lisset, Lazo del Vallín Sacha & Ferrer Bataille Elena. (2017) Clinical Evaluation of Terap C Vaccine in Combined Treatment with Interferon and Ribavirin in Patients with Hepatitis C. Current Therapeutic Research 85, pages 20-28.
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Nicholas A. Meanwell. (2016) 2015 Philip S. Portoghese Medicinal Chemistry Lectureship. Curing Hepatitis C Virus Infection with Direct-Acting Antiviral Agents: The Arc of a Medicinal Chemistry Triumph. Journal of Medicinal Chemistry 59:16, pages 7311-7351.
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Yang Wang, David R McGivern, Liang Cheng, Guangming Li, Stanley M Lemon, Junqi Niu, Lishan Su & Natalia J Reszka-Blanco. (2015) Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production. PLOS ONE 10:8, pages e0135232.
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VICTORIA ZISMANOV, OSHRAT ATTAR-SCHNEIDER, MICHAEL LISHNER, RACHEL HEFFEZ AIZENFELD, SHELLY TARTAKOVER MATALON & LIAT DRUCKER. (2015) Multiple myeloma proteostasis can be targeted via translation initiation factor eIF4E. International Journal of Oncology 46:2, pages 860-870.
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Sarah Allegra, Jessica Cusato, Amedeo De Nicolò, Lucio Boglione, Alberto Gatto, Giuseppe Cariti, Giovanni Di Perri & Antonio D’Avolio. (2015) Role of pharmacogenetic in ribavirin outcome prediction and pharmacokinetics in an Italian cohort of HCV-1 and 4 patients. Biomedicine & Pharmacotherapy 69, pages 47-55.
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Benjamin M. Wohl, Anton A.A. Smith, Bettina E.B. Jensen & Alexander N. Zelikin. (2014) Macromolecular (pro)drugs with concurrent direct activity against the hepatitis C virus and inflammation. Journal of Controlled Release 196, pages 197-207.
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Warren N. Schmidt, David R. Nelson, Jean–Michel Pawlotsky, Kenneth E. Sherman, David L. Thomas & Raymond T. Chung. (2014) Direct-Acting Antiviral Agents and the Path to Interferon Independence. Clinical Gastroenterology and Hepatology 12:5, pages 728-737.
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Mille B. L. Kryger, Anton A. A. Smith, Benjamin M. Wohl & Alexander N. Zelikin. (2014) Macromolecular Prodrugs for Controlled Delivery of Ribavirin. Macromolecular Bioscience 14:2, pages 173-185.
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Benjamin M. Wohl, Anton A. A. Smith, Mille B. L. Kryger & Alexander N. Zelikin. (2013) Narrow Therapeutic Window of Ribavirin as an Inhibitor of Nitric Oxide Synthesis is Broadened by Macromolecular Prodrugs. Biomacromolecules 14:11, pages 3916-3926.
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Monika Rau, Felix Stickel, Stefan Russmann, Christine N. Manser, Philip P. Becker, Michael Weisskopf, Johannes Schmitt, Michael T. Dill, Jean-François Dufour, Darius Moradpour, David Semela, Beat Müllhaupt & Andreas Geier. (2013) Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection. Journal of Hepatology 58:4, pages 669-675.
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Nicholas A. Meanwell, Stanley V. D'Andrea, Christopher W. Cianci, Ira B. Dicker, Kap-Sun Yeung, Makonen Belema & Mark Krystal. 2013. Drug Discovery. Drug Discovery 439 515 .
Rafael Bárcena, Ana Moreno, Miguel Angel Rodríguez-Gandía, Agustín Albillos, Carlos Arocena, Carlos Blesa, Fernando García-Hoz, Javier Graus, Javier Nuño, Pedro López-Hervás, Luis Gajate, Adolfo Martínez, Teresa Bermejo, María Luisa Mateos & Santos del Campo. (2013) Safety and anti-HCV effect of prolonged intravenous silibinin in HCV genotype 1 subjects in the immediate liver transplant period. Journal of Hepatology 58:3, pages 421-426.
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Emmanuel Thomas, Marc G Ghany & T Jake Liang. (2012) The Application and Mechanism of Action of Ribavirin in Therapy of Hepatitis C. Antiviral Chemistry and Chemotherapy 23:1, pages 1-12.
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Sandra Gemma, Stefania Butini, Giuseppe Campiani, Margherita Brindisi, Samantha Zanoli, Maria Pia Romano, Pierangela Tripaldi, Luisa Savini, Isabella Fiorini, Giuseppe Borrelli, Ettore Novellino & Giovanni Maga. (2011) Discovery of potent nucleotide-mimicking competitive inhibitors of hepatitis C virus NS3 helicase. Bioorganic & Medicinal Chemistry Letters 21:9, pages 2776-2779.
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Sheeja M. Krishnan & Narendra M. Dixit. (2011) Ribavirin-Induced Anemia in Hepatitis C Virus Patients Undergoing Combination Therapy. PLoS Computational Biology 7:2, pages e1001072.
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Shigekazu Nagata & Kohki Kawane. 2011. 139 161 .

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