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Drug Evaluation

Lansoprazole: pharmacokinetics, pharmacodynamics and clinical uses

Pages 1663-1670 | Published online: 24 Feb 2005

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Emad H. M. Hassanein, Fares E. M. Ali, Zuhair M. Mohammedsaleh, Ahmed M. Atwa & Mohamed Elfiky. (2023) The involvement of Nrf2/HO-1/cytoglobin and Ang-II/NF-κB signals in the cardioprotective mechanism of lansoprazole against cisplatin-induced heart injury. Toxicology Mechanisms and Methods 33:4, pages 316-326.
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Yuhai Bian & Ming Zhong. (2017) Investigation of the bioequivalence of two lansoprazole formulations in healthy Chinese volunteers after a single oral administration. Artificial Cells, Nanomedicine, and Biotechnology 45:7, pages 1425-1430.
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Martin G Gesheff, Christopher J Franzese, Kevin P Bliden, Chase J Contino, Rahil Rafeedheen, Udaya S Tantry & Paul A Gurbel. (2014) Review of pharmacokinetic and pharmacodynamic modeling and safety of proton pump inhibitors and aspirin. Expert Review of Clinical Pharmacology 7:5, pages 645-653.
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Parth J Parekh, Edward C Oldfield$suffix/text()$suffix/text() & David A Johnson. (2014) Treatment of gastroesophageal reflux disease: two new oral formulations dexlansoprazole MR and esomezol (esomeprazole strontium). Expert Opinion on Pharmacotherapy 15:9, pages 1215-1222.
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Articles from other publishers (33)

Neetu Soni, Rahul Maheshwari, Mayank Sharma & Vijay R. Chidrawar. (2023) Engineered dendritic architecture loaded with proton pump inhibitor for antibacterial therapy: Newer solution for gastric upset. Journal of Drug Delivery Science and Technology 89, pages 105109.
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Aneela Khushal, Umar Farooq, Sara Khan, Azhar Rasul, Tanveer A. Wani, Seema Zargar, Sohail Anjum Shahzad, Syed Majid Bukhari & Nazeer Ahmad Khan. (2023) Bioactivity-Guided Synthesis: In Silico and In Vitro Studies of β-Glucosidase Inhibitors to Cope with Hepatic Cytotoxicity. Molecules 28:18, pages 6548.
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Ming-Hsun Lin, Wen‐Tung Wu, Yong-Chen Chen, Tsung-Kun Lin, Yu‐Ching Chou & Chien‐An Sun. (2023) Association between clinical use of lansoprazole and the risk of type 2 diabetes mellitus: a pharmacoepidemiological cohort study. Diabetology & Metabolic Syndrome 15:1.
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Tomas Koltai, Larry Fliegel, Fátima Baltazar, Stephan J. Reshkin, Khalid O. Alfarouk, Rosa Angela Cardone & Julieta Afonso. 2023. pH Deregulation as the Eleventh Hallmark of Cancer. pH Deregulation as the Eleventh Hallmark of Cancer 81 86 .
Eman Darweish, Ahmed M. Abdel-Raoof, Hoda M. Marzouk, Ashraf M. Ashmawy, Yasmin M. Fayez & Maya S. Eissa. (2022) Innovative pH-dependent approach for electrochemical determination of a triple eradication therapy targeting H. Pylori infection in pharmaceutical formulation and human plasma sample: Modified electrode with Prussian blue analogue decorated multi-walled carbon nanotubes (PbA@MWCNT). Microchemical Journal 181, pages 107784.
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Eman Darweish, Maya S. Eissa, Yasmin M. Fayez & Hoda M. Marzouk. (2022) Ecofriendly high‐performance thin‐layer chromatography‐densitometric method for determination of a new triple pharmaceutical combination targeting Helicobacter pylori eradication along with greenness profile assessment . SEPARATION SCIENCE PLUS 5:7, pages 296-304.
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Eman Darweish, Maya S Eissa, Yasmin M Fayez & Hoda M Marzouk. (2021) Chromatographic estimation of a novel triple-therapy combination targeting Helicobacter pylori eradication in different matrices . Bioanalysis 13:20, pages 1547-1557.
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Mahdieh Darroudi, Ghodsi Mohammadi Ziarani, Shahriyar Bahar, Jahan B. Ghasemi & Alireza Badiei. (2021) Lansoprazole-Based Colorimetric Chemosensor for Efficient Binding and Sensing of Carbonate Ion: Spectroscopy and DFT Studies. Frontiers in Chemistry 8.
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Natalia Estrada-Ortiz, Elena Lopez-Gonzales, Ben Woods, Stefan Stürup, Inge A. M. de Graaf, Geny M. M. Groothuis & Angela Casini. (2019) Ex vivo toxicological evaluation of experimental anticancer gold(i) complexes with lansoprazole-type ligands. Toxicology Research 8:6, pages 885-895.
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Daniel Gutierrez, Loren D. Krueger, Andrea Tan, Joyce H. Park, George Lipkin & Shane A. Meehan. (2019) Proton pump inhibitor–induced erythema dyschromicum perstans–like pigmentation. JAAD Case Reports 5:8, pages 701-703.
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Shangshan Li & Jie Luan. (2018) Recent Advances on Relationship Between Inorganic Phosphate and Pathologic Calcification: Is Calcification After Breast Augmentation with Fat Grafting Correlated with Locally Increased Concentration of Inorganic Phosphate?. Aesthetic Plastic Surgery 43:1, pages 243-252.
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Binbin Wei, Yan Wang, Huizhe Wu, Mingyan Liu, Weifan Yao & Minjie Wei. (2019) Pharmacodynamics and Pharmacokinetics of a New Type of Compound Lansoprazole Capsule in Gastric Ulcer Rats and Beagle Dogs: Importance of Adjusting Oxidative Stress and Inflammation. Pharmaceutics 11:2, pages 49.
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Jiriporn Nantavishit, Varanuj Chatsudthipong & Sunhapas Soodvilai. (2018) Lansoprazole reduces renal cyst in polycystic kidney disease via inhibition of cell proliferation and fluid secretion. Biochemical Pharmacology 154, pages 175-182.
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Carolina Nicolau, Alyson Prorock, Yongde Bao, Ana Neves-Ferreira, Richard Valente & Jay Fox. (2018) Revisiting the Therapeutic Potential of Bothrops jararaca Venom: Screening for Novel Activities Using Connectivity Mapping. Toxins 10:2, pages 69.
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Menizibeya Osain WelcomeMenizibeya Osain Welcome. 2018. Gastrointestinal Physiology. Gastrointestinal Physiology 773 870 .
Parth J. Parekh & David A. Johnson. (2015) Medical treatment versus surgery for treatment of gastroesophageal reflux disease. Techniques in Gastrointestinal Endoscopy 17:2, pages 53-61.
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Maria V. Fawaz, Allen F. Brooks, Melissa E. Rodnick, Garrett M. Carpenter, Xia Shao, Timothy J. Desmond, Phillip Sherman, Carole A. Quesada, Brian G. Hockley, Michael R. Kilbourn, Roger L. Albin, Kirk A. Frey & Peter J. H. Scott. (2014) High Affinity Radiopharmaceuticals Based Upon Lansoprazole for PET Imaging of Aggregated Tau in Alzheimer’s Disease and Progressive Supranuclear Palsy: Synthesis, Preclinical Evaluation, and Lead Selection. ACS Chemical Neuroscience 5:8, pages 718-730.
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Ralph-Steven Wedemeyer & Henning Blume. (2014) Pharmacokinetic Drug Interaction Profiles of Proton Pump Inhibitors: An Update. Drug Safety 37:4, pages 201-211.
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In Young ParkByung Joo DoJae Sung AhnJae Hyuk LeeGye Yeon LeeSunhyung KimJeong-Hee Choi. (2014) Anaphylaxis to lansoprazole with tolerance to other proton pump inhibitors. Allergy, Asthma & Respiratory Disease 2:5, pages 383.
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Richard B. Silverman & Mark W. Holladay. 2014. The Organic Chemistry of Drug Design and Drug Action. The Organic Chemistry of Drug Design and Drug Action 423 468 .
Tina Kiffer-Moreira, Manisha C Yadav, Dongxing Zhu, Sonoko Narisawa, Campbell Sheen, Boguslaw Stec, Nicholas D Cosford, Russell Dahl, Colin Farquharson, Marc F Hoylaerts, Vicky E MacRae & José Luis Millán. (2013) Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification. Journal of Bone and Mineral Research 28:1, pages 81-91.
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Hiroshi Asajima, Naotaka Saito, Yoshinori Ohmura & Kazue Ohmura. (2011) Lansoprazole precipitated QT prolongation and torsade de pointes associated with disopyramide. European Journal of Clinical Pharmacology 68:3, pages 331-333.
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Laurian Vlase, Adina Popa, Maria Neag, Dana Muntean & Sorin E. Leucuta. (2011) Effect of Fluoxetine on the Pharmacokinetics of Lansoprazole. Clinical Drug Investigation 31:10, pages 727-733.
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Shaojun Shi & Ulrich Klotz. (2008) Proton pump inhibitors: an update of their clinical use and pharmacokinetics. European Journal of Clinical Pharmacology 64:10, pages 935-951.
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Desiree L. Tomilo, Patrick F. Smith, Abayomi B. Ogundele, Robin Difrancesco, Charles S. Berenson, Ellana Eberhardt, Edward Bednarczyk & Gene D. Morse. (2012) Inhibition of Atazanavir Oral Absorption by Lansoprazole Gastric Acid Suppression in Healthy Volunteers. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 26:3, pages 341-346.
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Henning Blume, Frank Donath, Andr?? Warnke & Barbara S Schug. (2006) Pharmacokinetic Drug Interaction Profiles of Proton Pump Inhibitors. Drug Safety 29:9, pages 769-784.
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J. Carcelén Andrés, C. Barroso Pérez, C. Fábrega Bosacoma, B. Feal Cortizas, V. Gallego Lago, E. Hidalgo Albert, M.T. Pozas del Río, A. Revert Molina-Niñirola, E. Valverde Molina & M.A. Wood Wood. (2005) Inhibidores de la bomba de protones en pediatría. Farmacia Hospitalaria 29:1, pages 43-54.
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D. A. Gremse, J. R. Donnelly, M. J. Kukulka, E. Lloyd & C. Lee. (2004) A novel option for dosing of proton pump inhibitors: dispersion of lansoprazole orally disintegrating tablet in water via oral syringe. Alimentary Pharmacology & Therapeutics 19:11, pages 1211-1215.
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J. Boulliat, E. Polard, F. Colin, D. Bentué-Ferrer & H. Allain. (2004) Encéphalopathie myoclonique : rôle des inhibiteurs de la pompe à protons. Revue Neurologique 160:3, pages 350-351.
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Dirk Roymans, Cis Van Looveren, Angelique Leone, J.Brandon Parker, Michael McMillian, Mark D. Johnson, Aruna Koganti, Ron Gilissen, Paul Silber, Geert Mannens & Willem Meuldermans. (2004) Determination of cytochrome P450 1A2 and cytochrome P450 3A4 induction in cryopreserved human hepatocytes. Biochemical Pharmacology 67:3, pages 427-437.
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Richard B. Silverman. 2004. The Organic Chemistry of Drug Design and Drug Action. The Organic Chemistry of Drug Design and Drug Action 497 557 .
Nelson Durán, Giselle Z Justo, Patrícia S Melo, Mariângela B.M De Azevedo, Alba R.M Souza Brito, Ana B.A Almeida & Marcela Haun. (2003) Evaluation of the antiulcerogenic activity of violacein and its modulation by the inclusion complexation with β-cyclodextrin. Canadian Journal of Physiology and Pharmacology 81:4, pages 387-396.
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Paola Tomassetti, Teresa Salomone, Marina Migliori, Davide Campana & Roberto Corinaldesi. (2003) Optimal Treatment of Zollinger-Ellison Syndrome and Related Conditions in Elderly Patients. Drugs & Aging 20:14, pages 1019-1034.
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