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Drug Evaluation

Evidence for the efficacy and safety of tolterodine in the treatment of overactive bladder

Pages 1685-1701 | Published online: 24 Feb 2005

Keep up to date with the latest research on this topic with citation updates for this article.

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Dean S Elterman, Bilal Chughtai, Steven A Kaplan & Jack Barkin. (2013) Tolterodine for the treatment of urge urinary incontinence. Expert Opinion on Pharmacotherapy 14:14, pages 1987-1991.
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Umberto Leone Roberti Maggiore, Stefano Salvatore, Franco Alessandri, Valentino Remorgida, Massimo Origoni, Massimo Candiani, Pier Luigi Venturini & Simone Ferrero. (2012) Pharmacokinetics and toxicity of antimuscarinic drugs for overactive bladder treatment in females. Expert Opinion on Drug Metabolism & Toxicology 8:11, pages 1387-1408.
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Ralph Peeker, Göran Samsioe, Jan Kowalski, Ann-Sofie Andersson & Agneta Bergqvist. (2010) A prospective observational study of the effects of treatment with extended-release tolterodine on health-related quality of life of patients suffering overactive bladder syndrome in Sweden. Scandinavian Journal of Urology and Nephrology 44:3, pages 138-146.
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Norman R Zinner. (2005) Trospium chloride: an anticholinergic quaternary ammonium compound for the treatment of overactive bladder. Expert Opinion on Pharmacotherapy 6:8, pages 1409-1420.
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Eric S Rovner. (2005) Tolterodine for the treatment of overactive bladder: a review. Expert Opinion on Pharmacotherapy 6:4, pages 653-666.
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Articles from other publishers (25)

Shizuo Yamada, Yoshihiko Ito, Saori Nishijima, Katsumi Kadekawa & Kimio Sugaya. (2018) Basic and clinical aspects of antimuscarinic agents used to treat overactive bladder. Pharmacology & Therapeutics 189, pages 130-148.
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Toshinobu Korenaga, Ryo Sasaki, Toshihide Takemoto, Toshihisa Yasuda & Masahito Watanabe. (2018) Computationally-Led Ligand Modification using Interplay between Theory and Experiments: Highly Active Chiral Rhodium Catalyst Controlled by Electronic Effects and CH-π Interactions. Advanced Synthesis & Catalysis 360:2, pages 322-333.
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Maryam Deldar Pasikhani, Zinat Ghanbari, Fateme Talei Khatibi, Ali Ganjalikhan Hakemi & Elaheh Miri Ashtiani. (2016) Comparing the Effect of Tolterodine, Biofeedback (Pelvic Floor Muscles Training) and Drug plus Biofeedback on Quality of Life and Urge Urinary Incontinency in Patients Referred to Imam Khomeini Hospital in 2014. Journal of Obstetrics, Gynecology and Cancer Research 1:3, pages 0-0.
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Yoshihiko Ito, Michishi Kashiwabara, Akira Yoshida, Eriko Hikiyama, Satomi Onoue & Shizuo Yamada. (2016) Muscarinic Receptor Binding in Rat Bladder Urothelium and Detrusor Muscle by Intravesical Solifenacin. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 39:7, pages 1167-1171.
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Michael B. Chancellor, David R. Staskin, Gary G. Kay, Bobby W. SandageJrJr, Michael G. Oefelein & Jack W. Tsao. (2012) Blood–Brain Barrier Permeation and Efflux Exclusion of Anticholinergics Used in the Treatment of Overactive Bladder. Drugs & Aging 29:4, pages 259-273.
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Won Hee PARK & Hyeong GON KIM. (2012) Low‐Dose Anticholinergic Combination Therapy in Male Benign Prostatic Hyperplasia Patients with Overactive Bladder Symptoms. LUTS: Lower Urinary Tract Symptoms 4:s1, pages 102-109.
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Shizuo YamadaShiori KuraokaAyaka OsanoYoshihiko Ito. (2012) Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of In Vivo Drug-Receptor Binding . International Neurourology Journal 16:3, pages 107.
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Emilio Sacco, Riccardo Bientinesi, Francesco Marangi, Alessandro D'addessi, Marco Racioppi, Gaetano Gulino, Francesco Pinto, Angelo Totaro & Pierfrancesco Bassi. (2011) Overactive Bladder Syndrome: The Social and Economic Perspective. Urologia Journal 78:4, pages 241-256.
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Akira Yoshida, Tomomi Fujino, Shuji Maruyama, Yoshihiko Ito, Yuko Taki & Shizuo Yamada. (2010) The Forefront for Novel Therapeutic Agents Based on the Pathophysiology of Lower Urinary Tract Dysfunction: Bladder Selectivity Based on In Vivo Drug–Receptor Binding Characteristics of Antimuscarinic Agents for Treatment of Overactive Bladder. Journal of Pharmacological Sciences 112:2, pages 142-150.
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Shuji Maruyama, Hideo Tsukada, Shingo Nishiyama, Takeharu Kakiuchi, Dai Fukumoto, Naoto Oku & Shizuo Yamada. (2008) In Vivo Quantitative Autoradiographic Analysis of Brain Muscarinic Receptor Occupancy by Antimuscarinic Agents for Overactive Bladder Treatment. Journal of Pharmacology and Experimental Therapeutics 325:3, pages 774-781.
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Kyu-Sung Lee, Hye Won Lee & Deok Hyun Han. (2008) Does anticholinergic medication have a role in treating men with overactive bladder and benign prostatic hyperplasia?. Naunyn-Schmiedeberg's Archives of Pharmacology 377:4-6, pages 491-501.
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Scott R. Armstrong, Sergio Briones, Brian Horger, Carrie L. Richardson, Sarah Jaw-Tsai & Sharath S. Hegde. (2007) Pharmacological analysis of the interaction of antimuscarinic drugs at M2 and M3 muscarinic receptors in vivo using the pithed rat assay. Naunyn-Schmiedeberg's Archives of Pharmacology 376:5, pages 341-349.
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Melinda Wuest. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference 1 8 .
Zhanna Jumadilova, Sujata Varadharajan, Prafulla GiraseDaniel A. Ollendorf. (2006) Retrospective evaluation of outcomes in patients with overactive bladder receiving tolterodine versus oxybutynin. American Journal of Health-System Pharmacy 63:23, pages 2357-2364.
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Steven A. Kaplan, Claus G. Roehrborn, Roger Dmochowski, Eric S. Rovner, Joseph T. Wang & Zhonghong Guan. (2006) Tolterodine extended release improves overactive bladder symptoms in men with overactive bladder and nocturia. Urology 68:2, pages 328-332.
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M. R. Ruggieri & A. S. Braverman. (2006) Regulation of bladder muscarinic receptor subtypes by experimental pathologies. Autonomic and Autacoid Pharmacology 26:3, pages 311-325.
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C.D. Anthony Herndon & David B. Joseph. (2006) Urinary Incontinence. Pediatric Clinics of North America 53:3, pages 363-377.
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CLAUS G. ROEHRBORN, PAUL ABRAMS, ERIC S. ROVNER, STEVEN A. KAPLAN, SENDER HERSCHORN & ZHONGHONG GUAN. (2006) Efficacy and tolerability of tolterodine extended-release in men with overactive bladder and urgency urinary incontinence. BJU International 97:5, pages 1003-1006.
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Stephen J. Griffin & William H. Turner. 2006. Drug Treatment in Urology. Drug Treatment in Urology 1 20 .
MICHAEL R. RUGGIERI, ALAN S. BRAVERMAN & MICHEL A. PONTARI. (2005) COMBINED USE OF α-ADRENERGIC AND MUSCARINIC ANTAGONISTS FOR THE TREATMENT OF VOIDING DYSFUNCTION. Journal of Urology 174:5, pages 1743-1748.
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KYU-SUNG LEE, MYUNG-SOO CHOO, DUK-YOON KIM, JOON CHUL KIM, HYUNG-JEE KIM, KWEON SIK MIN, JONG BOUK LEE, HEE JONG JEONG, TACK LEE & WON HEE PARK. (2005) COMBINATION TREATMENT WITH PROPIVERINE HYDROCHLORIDE PLUS DOXAZOSIN CONTROLLED RELEASE GASTROINTESTINAL THERAPEUTIC SYSTEM FORMULATION FOR OVERACTIVE BLADDER AND COEXISTING BENIGN PROSTATIC OBSTRUCTION: A PROSPECTIVE, RANDOMIZED, CONTROLLED MULTICENTER STUDY. Journal of Urology 174:4 Part 1, pages 1334-1338.
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Stefano Salvatore, Marco Soligo, Fabio Proietti, Stefania Citterio, Walter Artibani & Rodolfo Milani. (2005) Overactive bladder syndrome: considerations in pharmacotherapy and new perspectives. European Journal of Obstetrics & Gynecology and Reproductive Biology 120:2, pages 129-133.
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Stefano Salvatore, Vikram Khullar, Linda Cardozo, Rodolfo Milani, Stavros Athanasiou & Con Kelleher. (2005) Long-term prospective randomized study comparing two different regimens of oxybutynin as a treatment for detrusor overactivity. European Journal of Obstetrics & Gynecology and Reproductive Biology 119:2, pages 237-241.
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Alan D Garely & Lara Burrows. (2004) Benefit-Risk Assessment of Tolterodine in the Treatment of Overactive Bladder in Adults. Drug Safety 27:13, pages 1043-1057.
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TOMOHIRO UEDA, GRANNUM R. SANT, PHILIP M. HANNO & NAOKI YOSHIMURA. (2003) Interstitial cystitis and frequency-urgency syndrome (OAB syndrome). International Journal of Urology 10, pages S39-S48.
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