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Drug Evaluations

Irinotecan and bevacizumab in recurrent glioblastoma multiforme

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Pages 825-833 | Published online: 09 Mar 2011

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Xiaohong Xie, Shangyi Bao, Hong Zhao, Liuying Li & Xiaojun Fu. (2023) Efficacy and Safety of Bevacizumab for Treating Glioblastoma: A Systematic Review and Meta-Analysis of Phase II and III Randomized Controlled Trials. Cancer Investigation 41:3, pages 305-317.
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Zhouqing Chen, Na Xu, Chongshun Zhao, Tao Xue, Xin Wu & Zhong Wang. (2018) Bevacizumab combined with chemotherapy vs single-agent therapy in recurrent glioblastoma: evidence from randomized controlled trials. Cancer Management and Research 10, pages 2193-2205.
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Ulrik Lassen, Morten Mau-Sørensen & Hans Skovgaard Poulsen. (2014) Orphan drugs in glioblastoma multiforme: a review. Orphan Drugs: Research and Reviews 4, pages 83-91.
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Hans Skovgaard Poulsen, Thomas Urup, Signe Regner Michaelsen, Mikkel Staberg, Mette Villingshøj & Ulrik Lassen. (2014) The impact of bevacizumab treatment on survival and quality of life in newly diagnosed glioblastoma patients. Cancer Management and Research 6, pages 373-387.
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Articles from other publishers (26)

Elisa Checa-Chavarria, Eva Rivero-Buceta, Miguel Angel Sanchez Martos, Gema Martinez Navarrete, Cristina Soto-Sánchez, Pablo Botella & Eduardo Fernández. (2021) Development of a Prodrug of Camptothecin for Enhanced Treatment of Glioblastoma Multiforme. Molecular Pharmaceutics 18:4, pages 1558-1572.
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Nathan McDannold, Yongzhi Zhang, Jeffrey G. Supko, Chanikarn Power, Tao Sun, Natalia Vykhodtseva, Alexandra J. Golby & David A. Reardon. (2020) Blood-brain barrier disruption and delivery of irinotecan in a rat model using a clinical transcranial MRI-guided focused ultrasound system. Scientific Reports 10:1.
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Qimeihui Wang, Guoqing Sui, Xiaoli Wu, Dengke Teng, Lingyu Zhu, Shihui Guan, Haitao Ran, Zhigang Wang & Hui Wang. (2020) A sequential targeting nanoplatform for anaplastic thyroid carcinoma theranostics. Acta Biomaterialia 102, pages 367-383.
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A. F. Cardona, L. Rojas, B. Wills, A. Ruiz-Patiño, L. Abril, F. Hakim, E. Jiménez, N. Useche, S. Bermúdez, J. A. Mejía, J. F. Ramón, H. Carranza, C. Vargas, J. Otero, P. Archila, J. Rodríguez, J. Rodríguez, J. Behaine, D. González, J. Jacobo, H. Cifuentes, O. Feo, P. Penagos, D. Pineda, L. Ricaurte, L. E. Pino, C. Vargas, J. C. Marquez, M. I. Mantilla, L. D. Ortiz, C. Balaña, R. Rosell, Z. L. Zatarain-Barrón & O. Arrieta. (2019) A comprehensive analysis of factors related to carmustine/bevacizumab response in recurrent glioblastoma. Clinical and Translational Oncology 21:10, pages 1364-1373.
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Anupriya Anand, Abimanyu Sugumaran & Damodharan Narayanasamy. (2019) Brain targeted delivery of anticancer drugs: prospective approach using solid lipid nanoparticles. IET Nanobiotechnology 13:4, pages 353-362.
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Nataliya Zhukova, Revathi Rajagopal, Adrienne Lam, Lee Coleman, Peter Shipman, Thomas Walwyn, Molly Williams, Michael Sullivan, Martin Campbell, Kanika Bhatia, Nicholas G. Gottardo & Jordan R. Hansford. (2019) Use of bevacizumab as a single agent or in adjunct with traditional chemotherapy regimens in children with unresectable or progressive low-grade glioma. Cancer Medicine 8:1, pages 40-50.
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J. N. Jakobsen, T. Urup, K. Grunnet, A. Toft, M. D. Johansen, S. H. Poulsen, I. J. Christensen, A. Muhic & H. S. Poulsen. (2018) Toxicity and efficacy of lomustine and bevacizumab in recurrent glioblastoma patients. Journal of Neuro-Oncology 137:2, pages 439-446.
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Ok-Sun KimJang Woo ParkEun Sang LeeRan Ji YooWon-Il KimKyo Chul LeeJae Hoon ShimHye Kyung Chung. (2018) [ 18 F]FET PET is a useful tool for treatment evaluation and prognosis prediction of anti-angiogenic drug in an orthotopic glioblastoma mouse model . Laboratory Animal Research 34:4, pages 248.
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Rongrong Zhu, Zhaoqi Wang, Peng Liang, Xiaolie He, Xizhen Zhuang, Ruiqi Huang, Mei Wang, Qigang Wang, Yechang Qian & Shilong Wang. (2017) Efficient VEGF targeting delivery of DOX using Bevacizumab conjugated SiO2@LDH for anti-neuroblastoma therapy. Acta Biomaterialia 63, pages 163-180.
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Giuseppe Lombardi, Ardi Pambuku, Luisa Bellu, Miriam Farina, Alessandro Della Puppa, Luca Denaro & Vittorina Zagonel. (2017) Effectiveness of antiangiogenic drugs in glioblastoma patients: A systematic review and meta-analysis of randomized clinical trials. Critical Reviews in Oncology/Hematology 111, pages 94-102.
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Yuping Li, Mengzhuo Hou, Guangyu Lu, Natalia Ciccone, Xingdong Wang & Hengzhu Zhang. (2016) The Prognosis of Anti-Angiogenesis Treatments Combined with Standard Therapy for Newly Diagnosed Glioblastoma: A Meta-Analysis of Randomized Controlled Trials. PLOS ONE 11:12, pages e0168264.
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Luigi Battaglia, Marina Gallarate, Elena Peira, Daniela Chirio, Ilaria Solazzi, Susanna Marzia Adele Giordano, Casimiro Luca Gigliotti, Chiara Riganti & Chiara Dianzani. (2015) Bevacizumab loaded solid lipid nanoparticles prepared by the coacervation technique: preliminary in vitro studies . Nanotechnology 26:25, pages 255102.
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R. Rahman, K. Hempfling, A. D. Norden, D. A. Reardon, L. Nayak, M. L. Rinne, R. Beroukhim, L. Doherty, S. Ruland, A. Rai, J. Rifenburg, D. LaFrankie, B. M. Alexander, R. Y. Huang, P. Y. Wen & E. Q. Lee. (2014) Retrospective study of carmustine or lomustine with bevacizumab in recurrent glioblastoma patients who have failed prior bevacizumab. Neuro-Oncology 16:11, pages 1523-1529.
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Kelong Han, Jin Jin, Mauricio Maia, John Lowe, Martina A. Sersch & David E. Allison. (2014) Lower Exposure and Faster Clearance of Bevacizumab in Gastric Cancer and the Impact of Patient Variables: Analysis of Individual Data from AVAGAST Phase III Trial. The AAPS Journal 16:5, pages 1056-1063.
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Raymond Y. Huang, Rifaquat Rahman, Alhafidz Hamdan, Caroline Kane, Christina Chen, Andrew D. Norden, David A. Reardon, Srinivasan Mukundun & Patrick Y. Wen. (2013) Recurrent glioblastoma: Volumetric assessment and stratification of patient survival with early posttreatment magnetic resonance imaging in patients treated with bevacizumab. Cancer 119:19, pages 3479-3488.
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Linda Sooman, Simon Ekman, Claes Andersson, Hanna Göransson Kultima, Anders Isaksson, Fredrik Johansson, Michael Bergqvist, Erik Blomquist, Johan Lennartsson & Joachim Gullbo. (2013) Synergistic interactions between camptothecin and EGFR or RAC1 inhibitors and between imatinib and Notch signaling or RAC1 inhibitors in glioblastoma cell lines. Cancer Chemotherapy and Pharmacology 72:2, pages 329-340.
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J. L. Boxerman, Z. Zhang, Y. Safriel, M. Larvie, B. S. Snyder, R. Jain, T. L. Chi, A. G. Sorensen, M. R. Gilbert & D. P. Barboriak. (2013) Early post-bevacizumab progression on contrast-enhanced MRI as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 Central Reader Study. Neuro-Oncology 15:7, pages 945-954.
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E.-M. Ratai, Z. Zhang, B. S. Snyder, J. L. Boxerman, Y. Safriel, R. C. McKinstry, F. Bokstein, M. R. Gilbert, A. G. Sorensen & D. P. Barboriak. (2013) Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677. Neuro-Oncology 15:7, pages 936-944.
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J.-M. Escoffre, A. Novell, S. Serrière, T. Lecomte & A. Bouakaz. (2013) Irinotecan Delivery by Microbubble-Assisted Ultrasound: In Vitro Validation and a Pilot Preclinical Study . Molecular Pharmaceutics 10:7, pages 2667-2675.
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Yongzhi Wang & Tao Jiang. (2013) Understanding high grade glioma: Molecular mechanism, therapy and comprehensive management. Cancer Letters 331:2, pages 139-146.
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Iben Kümler, Nils Brünner, Jan Stenvang, Eva Balslev & Dorte L. Nielsen. (2013) A systematic review on topoisomerase 1 inhibition in the treatment of metastatic breast cancer. Breast Cancer Research and Treatment 138:2, pages 347-358.
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Jing Li, Manish Gupta, Denise Jin, Yan Xin, Jennifer Visich & David E. Allison. (2012) Characterization of the long-term pharmacokinetics of bevacizumab following last dose in patients with resected stage II and III carcinoma of the colon. Cancer Chemotherapy and Pharmacology 71:3, pages 575-580.
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Aurélien Corroyer-Dulmont, Elodie A. Pérès, Edwige Petit, Jean-Sébastien Guillamo, Nathalie Varoqueaux, Simon Roussel, Jérôme Toutain, Didier Divoux, Eric T. MacKenzie, Jérôme Delamare, Méziane Ibazizène, Myriam Lecocq, Andréas H. Jacobs, Louisa Barré, Myriam Bernaudin & Samuel Valable. (2013) Detection of glioblastoma response to temozolomide combined with bevacizumab based on µMRI and µPET imaging reveals [18F]-fluoro-l-thymidine as an early and robust predictive marker for treatment efficacy. Neuro-Oncology 15:1, pages 41-56.
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Aida Muhic, Hans Skovgaard Poulsen, Morten Sorensen, Kirsten Grunnet & Ulrik Lassen. (2012) Phase II open-label study of nintedanib in patients with recurrent glioblastoma multiforme. Journal of Neuro-Oncology 111:2, pages 205-212.
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Guobin Zhang, Shengyue Huang & Zhongcheng Wang. (2012) A meta-analysis of bevacizumab alone and in combination with irinotecan in the treatment of patients with recurrent glioblastoma multiforme. Journal of Clinical Neuroscience 19:12, pages 1636-1640.
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Hana Yu, Junseong Park, Jungsul Lee, Kyungsun Choi & Chulhee Choi. (2012) Constitutive Expression of MAP Kinase Phosphatase-1 Confers Multi-drug Resistance in Human Glioblastoma Cells. Cancer Research and Treatment 44:3, pages 195-201.
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