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Drug Evaluations

Agomelatine for the treatment of major depressive disorder

, MD & , MD
Pages 2411-2419 | Published online: 15 Sep 2011

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Trevor R. Norman & James S. Olver. (2019) Agomelatine for depression: expanding the horizons?. Expert Opinion on Pharmacotherapy 20:6, pages 647-656.
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Susan G Kornstein, Roger S McIntyre, Michael E Thase & Matthieu Boucher. (2014) Desvenlafaxine for the treatment of major depressive disorder. Expert Opinion on Pharmacotherapy 15:10, pages 1449-1463.
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Massimiliano Buoli, Massimo Carlo Mauri & Alfredo Carlo Altamura. (2014) Pharmacokinetic evaluation of agomelatine for the treatment of generalised anxiety disorder. Expert Opinion on Drug Metabolism & Toxicology 10:6, pages 885-892.
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Jan Pecenak. (2013) Agomelatine as monotherapy for major depression: an outpatient, open-label study. Neuropsychiatric Disease and Treatment 9, pages 1595-1604.
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Trevor R Norman. (2013) Agomelatine, melatonin and depressive disorder. Expert Opinion on Investigational Drugs 22:4, pages 407-410.
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Ludovit Paulis, Fedor Simko & Moshe Laudon. (2012) Cardiovascular effects of melatonin receptor agonists. Expert Opinion on Investigational Drugs 21:11, pages 1661-1678.
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Frank I Tarazi & Stephen M Stahl. (2012) Iloperidone, asenapine and lurasidone: a primer on their current status. Expert Opinion on Pharmacotherapy 13:13, pages 1911-1922.
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Chun Yang, Wen-yuan Li, Zhi-qiang Zhou & Jian-jun Yang. (2011) Innovative antidepressants: jumping out of the monoamine-based theory?. Expert Opinion on Pharmacotherapy 12:18, pages 2929-2930.
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Jozef Višňovský & Jakub Vaněk. (2023) New pharmaceuticals in the treatment of insomnia. Psychiatrie pro praxi 24:3, pages 176-179.
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Sheikh Bilal Ahmad, Aarif Ali, Midhat Bilal, Shahzada Mudasir Rashid, Amir Bashir Wani, Rahil Razak Bhat & Muneeb U. Rehman. (2023) Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders. Cellular and Molecular Neurobiology 43:6, pages 2437-2458.
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Mei Gao, Kai Chen, Wei Gu, Xiaoyu Liu, Tianbin Liu, Yong Ying, Chong Cao, Yanhua Zhang, Daizhou Zhang & Guiwen Yang. (2022) 28‐day repeated dose toxicity and toxicokinetics study on new melatonergic antidepressant GW117 in beagle dogs. Journal of Applied Toxicology 43:4, pages 577-588.
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Mei Gao, Hui Ma, Tianbin Liu, Chong Cao, Zhiyong Zheng, Liansheng Tang, Wei Gu, Daizhou Zhang & Haiji Sun. (2023) Acute toxicity and genotoxicity studies on new melatonergic antidepressant GW117. Heliyon 9:3, pages e14026.
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琳琳 董. (2022) New Progress in the Treatment of Elderly Depression. Advances in Clinical Medicine 12:08, pages 7123-7128.
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Xin Ma, Jing Cao, Hailin Zheng, Xinchun Mei, Meijuan Wang, Haoran Wang, Yu Shuai & Yuan Shen. (2021) Peripheral body temperature rhythm is associated with suicide risk in major depressive disorder: a case-control study. General Psychiatry 34:1, pages e100219.
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Chelsea A. Vadnie, Lauren M. DePoy & Colleen A. McClung. 2021. Circadian Clocks. Circadian Clocks 69 78 .
Qiushi Yang, Xuelin Zhou, Jingyi Li, Yi Ma, Li Lu, Jie Xiong, Pingxiang Xu, Yuhang Li, Yi Chen, Wei Gu, Ming Xue, Zengliang Jin & Xiaorong Li. (2019) Sub-Acute Oral Toxicity of a Novel Derivative of Agomelatine in Rats in a Sex-Dependent Manner. Frontiers in Pharmacology 10.
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Chelsea A. Vadnie & Colleen A. McClung. (2017) Circadian Rhythm Disturbances in Mood Disorders: Insights into the Role of the Suprachiasmatic Nucleus. Neural Plasticity 2017, pages 1-28.
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Daniel J. Buysse & Shachi Tyagi. 2017. Principles and Practice of Sleep Medicine. Principles and Practice of Sleep Medicine 432 445.e7 .
Fang Tang, Rui Zhou, Zeneng Cheng, Guoping Yang, Aiqiao Chen, Zhi Liu, Hongyi Tan, Shuang Yang, Sanwang Li, Lingli Mu & Peng Yu. (2016) Implementation of a reference-scaled average bioequivalence approach for highly variable generic drug products of agomelatine in Chinese subjects. Acta Pharmaceutica Sinica B 6:1, pages 71-78.
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Ryan W. Logan, Nicole Edgar, Andrea G. Gillman, Daniel Hoffman, Xiyu Zhu & Colleen A. McClung. (2015) Chronic Stress Induces Brain Region-Specific Alterations of Molecular Rhythms that Correlate with Depression-like Behavior in Mice. Biological Psychiatry 78:4, pages 249-258.
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Moshe Laudon & Anat Frydman-Marom. (2014) Therapeutic Effects of Melatonin Receptor Agonists on Sleep and Comorbid Disorders. International Journal of Molecular Sciences 15:9, pages 15924-15950.
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Paul Willner, Jørgen Scheel-Krüger & Catherine Belzung. (2014) Resistance to antidepressant drugs. Behavioural Pharmacology 25:5 and 6, pages 352-371.
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Kai-Lin Huang, Wan-Chen Lu, Ying-Yue Wang, Gwo-Chi Hu, Chien-Hung Lu, Wei-Ying Lee & Chien-Chi Hsu. (2014) Comparison of agomelatine and selective serotonin reuptake inhibitors/serotonin–norepinephrine reuptake inhibitors in major depressive disorder: A meta-analysis of head-to-head randomized clinical trials. Australian & New Zealand Journal of Psychiatry 48:7, pages 663-671.
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Nori Tolosa de Talamoni, Vanessa Andrea Areco, Maria Elena Peralta Lopez, Gabriela Diaz de Barboza, Maria Angelica Rivoira & Agata Rita Carpentieri. 2014. Melatonin and Melatonergic Drugs in Clinical Practice. Melatonin and Melatonergic Drugs in Clinical Practice 27 42 .
Hui Ling Tan. (2013) Agomelatine-induced gynaecomastia. Australian & New Zealand Journal of Psychiatry 47:12, pages 1211-1212.
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Paul Willner, Jørgen Scheel-Krüger & Catherine Belzung. (2013) The neurobiology of depression and antidepressant action. Neuroscience & Biobehavioral Reviews 37:10, pages 2331-2371.
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Giovanni Martinotti, Gianna Sepede, Francesco Gambi, Giuseppe Di Iorio, Domenico De Berardis, Marco Di Nicola, Marco Onofrj, Luigi Janiri & Massimo Di Giannantonio. (2012) Agomelatine Versus Venlafaxine XR in the Treatment of Anhedonia in Major Depressive Disorder. Journal of Clinical Psychopharmacology 32:4, pages 487-491.
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Dan J SteinTracy L GreerBenji T KurianMadhukar H Trivedi. 2012. Antidepressants and Major Depressive Disorder. Antidepressants and Major Depressive Disorder 108 119 .
Makoto Kamata, Toshiro Yamashita, Toshihiro Imaeda, Toshio Tanaka, Shinichi Masada, Masahiro Kamaura, Shizuo Kasai, Ryoma Hara, Shigekazu Sasaki, Shiro Takekawa, Asano Asami, Tomoko Kaisho, Nobuhiro Suzuki, Shuntaro Ashina, Hitomi Ogino, Yoshihide Nakano, Yasutaka Nagisa, Koki Kato, Kaneyoshi Kato & Yuji Ishihara. (2012) Melanin-Concentrating Hormone Receptor 1 Antagonists. Synthesis and Structure–Activity Relationships of Novel 3-(Aminomethyl)quinolines. Journal of Medicinal Chemistry 55:5, pages 2353-2366.
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