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Expert Opinion on Pharmacotherapy Volume 12, 2011 - Issue 15
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Drug Evaluations

Omacetaxine mepesuccinate for the treatment of leukemia

Theo Daniel Kim Medizinische Klinik m.S. Hämatologie und Onkologie, Charité–Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany+49 30 450 653 619; +49 30 450 553 964; [email protected]
, MD,
Mareike Frick Medizinische Klinik m.S. Hämatologie und Onkologie, Charité–Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany+49 30 450 653 619; +49 30 450 553 964; [email protected]
, MD &
Philipp le Coutre Medizinische Klinik m.S. Hämatologie und Onkologie, Charité–Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany+49 30 450 653 619; +49 30 450 553 964; [email protected]
, MD
Pages 2381-2392 | Published online: 15 Sep 2011

Citations (13)

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Yaoyu Chen & Shaoguang Li. (2014) Omacetaxine mepesuccinate in the treatment of intractable chronic myeloid leukemia. OncoTargets and Therapy 7, pages 177-186.
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Articles from other publishers (12)

Yujian Yang, Qiuchun Yu, Lean Hu, Botao Dai, Ruxi Qi, Yu Chang, Qingwen Zhang, Zhang Zhang, Yingjun Li & Xumu Zhang. (2022) Enantioselective semisynthesis of novel cephalotaxine esters with potent antineoplastic activities against leukemia. European Journal of Medicinal Chemistry 244, pages 114731.
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Aleksandra Sochacka-Ćwikła, Marcin Mączyński & Andrzej Regiec. (2021) FDA-Approved Drugs for Hematological Malignancies—The Last Decade Review. Cancers 14:1, pages 87.
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Doudou Yan, Hui Wei, Xinning Lai, Yangyang Ge, Shilin Xu, Jie Meng, Tao Wen, Jian Liu, Weiqi Zhang, Jianxiang Wang & Haiyan Xu. (2020) Co-delivery of homoharringtonine and doxorubicin boosts therapeutic efficacy of refractory acute myeloid leukemia. Journal of Controlled Release 327, pages 766-778.
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Lele Wang, Linlin Zhao, Guo Wei, Dieter Saur, Barbara Seidler, Junyan Wang, Chuanxin Wang & Tonggang Qi. (2018) Homoharringtonine could induce quick protein synthesis of PSMD11 through activating MEK1/ERK1/2 signaling pathway in pancreatic cancer cells. Journal of Cellular Biochemistry 119:8, pages 6644-6656.
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Quincy Quick. (2018) Microtubule-Actin Crosslinking Factor 1 and Plakins as Therapeutic Drug Targets. International Journal of Molecular Sciences 19:2, pages 368.
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Matthew Trendowski. (2015) Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products. Drugs 75:17, pages 1993-2016.
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Hagop Kantarjian, Susan O'Brien, Elias Jabbour, Gisoo Barnes, Ashutosh Pathak & Jorge Cortes. (2015) Effectiveness of Homoharringtonine (Omacetaxine Mepesuccinate) for Treatment of Acute Myeloid Leukemia: A Meta-Analysis of Chinese Studies. Clinical Lymphoma Myeloma and Leukemia 15:1, pages 13-21.
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Gayong Shim, Sangbin Lee, Junhyeok Choi, Soondong Lee, Chan-Wha Kim & Yu-Kyoung Oh. (2014) Liposomal Co-Delivery of Omacetaxine Mepesuccinate and Doxorubicin for Synergistic Potentiation of Antitumor Activity. Pharmaceutical Research 31:8, pages 2178-2185.
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Giuseppe Saglio & Carmen FavaStephan Joseph Dorkhom, Hady Ghanem & Elias Jabbour. 2013. The Treatment of Chronic Myeloid Leukemia. The Treatment of Chronic Myeloid Leukemia 78 96 .
Lenka Beranova, Antonio R. Pombinho, Jarmila Spegarova, Michal Koc, Magdalena Klanova, Jan Molinsky, Pavel Klener, Petr Bartunek & Ladislav Andera. (2013) The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms. Apoptosis 18:6, pages 739-750.
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Joanne Bronson, Amelia Black, T. G. Murali Dhar, Bruce A. Ellsworth & J. Robert Merritt. 2013. 471 546 .
Hemant Kulkarni, Harald H H Göring, Vincent Diego, Shelley Cole, Ken R Walder, Greg R Collier, John Blangero & Melanie A Carless. (2012) Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines. BMC Medical Genomics 5:1.
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