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Expert Opinion on Pharmacotherapy Volume 13, 2012 - Issue 9
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Drug Evaluations

Extended-release niacin with laropiprant: a review on efficacy, clinical effectiveness and safety

Rahul YadavUniversity of Manchester, School of Biomedicine, Cardiovascular Research Group, Core Technology Facility, 46, Grafton Street, Manchester, UK
, MRCP,
Michael FranceCentral Manchester University Hospitals NHS Foundation Trust, Department of Clinical Biochemistry, Manchester, UK
, FRCPath,
Naveed YounisUniversity Hospital of South Manchester NHS Foundation Trust, Department of Diabetes and Endocrinology, Southmoor Road, Manchester, UK
, MD,
Salam HamaUniversity of Manchester, School of Biomedicine, Cardiovascular Research Group, Core Technology Facility, 46, Grafton Street, Manchester, UK
, MSc,
Basil J AmmoriThe University of Manchester, and Consultant Surgeon, Salford Royal NHS Foundation Trust, Stott Lane, Salford, UK
, MD,
See KwokUniversity of Manchester, School of Biomedicine, Cardiovascular research group, Core Technology Facility, 46, Grafton street, Manchester, M13 9NT, UK
, MD &
Handrean SoranUniversity Department of Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK+0044 0 161 276 4443/4066; +0044 0 161 276 3630; [email protected]; [email protected]
, MD show all
Pages 1345-1362 | Published online: 21 May 2012

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Michael France. (2014) The withdrawal of the thyromimetic eprotirome. Clinical Lipidology 9:5, pages 483-486.
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Michael France, Jonathan Schofield, See Kwok & Handrean Soran. (2014) Treatment of homozygous familial hypercholesterolemia. Clinical Lipidology 9:1, pages 101-118.
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Atul Ashok Kalanuria, Paul Nyquist & Geoffrey Ling. (2012) The prevention and regression of atherosclerotic plaques: emerging treatments. Vascular Health and Risk Management 8, pages 549-561.
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Mario Cozzolino, Elena Bruschetta, Daniele Cusi, Emanuele Montanari, Maria Enrica Giovenzana & Andrea Galassi. (2012) Phosphate handling in CKD-MBD from stage 3 to dialysis and the three strengths of lanthanum carbonate. Expert Opinion on Pharmacotherapy 13:16, pages 2337-2353.
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Articles from other publishers (20)

Erik T. Diniz, Ana Carolina S. M. Cardoso & Francisco Bandeira. 2022. Endocrinology and Diabetes. Endocrinology and Diabetes 461 472 .
Karen Alejandra Méndez-Lara, David Santos, Núria Farré, Madalina Nicoleta Nan, Víctor Pallarès, Antonio Pérez-Pérez, Núria Alonso, Joan Carles Escolà-Gil, Francisco Blanco-Vaca & Josep Julve. (2019) Vitamin B3 impairs reverse cholesterol transport in Apolipoprotein E-deficient mice. Clínica e Investigación en Arteriosclerosis 31:6, pages 251-260.
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Karen Alejandra Méndez-Lara, David Santos, Núria Farré, Madalina Nicoleta Nan, Víctor Pallarès, Antonio Pérez-Pérez, Núria Alonso, Joan Carles Escolà-Gil, Francisco Blanco-Vaca & Josep Julve. (2019) Vitamin B3 impairs reverse cholesterol transport in Apolipoprotein E-deficient mice. Clínica e Investigación en Arteriosclerosis (English Edition) 31:6, pages 251-260.
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Maria Guarino & Jean-François Dufour. (2019) Nicotinamide and NAFLD: Is There Nothing New Under the Sun?. Metabolites 9:9, pages 180.
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Amir Abbas Momtazi‐Borojeni, Niki Katsiki, Matteo Pirro, Maciej Banach, Khalid Al Rasadi & Amirhossein Sahebkar. (2019) Dietary natural products as emerging lipoprotein(a)‐lowering agents. Journal of Cellular Physiology 234:8, pages 12581-12594.
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Gaber Moustafa, Hemat Khalaf, Ahmed Naglah, Asma Al-Wasidi, Nawal Al-Jafshar & Hassan Awad. (2018) Synthesis, Molecular Docking Studies, In Vitro Antimicrobial and Antifungal Activities of Novel Dipeptide Derivatives Based on N-(2-(2-Hydrazinyl-2-oxoethylamino)-2-oxoethyl)-Nicotinamide. Molecules 23:4, pages 761.
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Regina Appiah-Opong, Isaac Tuffour, Ebenezer Ofori-Attah, Abigail Aning, Philip Atchoglo, Eunice Ampem Danso, Believe Ahedor, Samuel Adjei & Alexander K. Nyarko. (2018) In Vivo Modulation of Rat Liver Microsomal Cytochrome P450 Activity by Antimalarial, Anti-HIV, and Antituberculosis Plant Medicines. Journal of Evidence-Based Integrative Medicine 23, pages 2515690X1881000.
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Stefan Offermanns. (2017) Hydroxy-Carboxylic Acid Receptor Actions in Metabolism. Trends in Endocrinology & Metabolism 28:3, pages 227-236.
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Amutha Iswarya Devi Jeyaraman & Kottai Muthu Arumugam. (2015) Hypolipidemic effect of ethanolic extract from whole plant of Lactuca runcinata (DC.) in atherogenic diet induced hyperlipidemic rats. African Journal of Pharmacy and Pharmacology 9:47, pages 1080-1087.
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Ulrich Julius. (2015) Niacin as antidyslipidemic drug. Canadian Journal of Physiology and Pharmacology 93:12, pages 1043-1054.
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Rahul Yadav, Yifen Liu, See Kwok, Salam Hama, Michael France, Ruth Eatough, Phil Pemberton, Jonathan Schofield, Tarza J. Siahmansur, Rayaz Malik, Basil A. Ammori, Basil Issa, Naveed Younis, Rachelle Donn, Adam Stevens, Paul Durrington & Handrean Soran. (2015) Effect of Extended‐Release Niacin on High‐Density Lipoprotein (HDL) Functionality, Lipoprotein Metabolism, and Mediators of Vascular Inflammation in Statin‐Treated Patients. Journal of the American Heart Association 4:9.
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Dustin L. Cooper, Derek E. Murrell, David S. Roane & Sam Harirforoosh. (2015) Effects of formulation design on niacin therapeutics: mechanism of action, metabolism, and drug delivery. International Journal of Pharmaceutics 490:1-2, pages 55-64.
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Miao Hu, Ya-Ling Yang, Daisaku Masuda, Shizuya Yamashita & Brian Tomlinson. (2015) Effect of Extended-Release Niacin/Laropiprant Combination on Plasma Adiponectin and Insulin Resistance in Chinese Patients with Dyslipidaemia. Disease Markers 2015, pages 1-8.
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Nujarin Sinthupoom, Veda Prachayasittikul, Supaluk Prachayasittikul, Somsak Ruchirawat & Virapong Prachayasittikul. (2014) Nicotinic acid and derivatives as multifunctional pharmacophores for medical applications. European Food Research and Technology 240:1, pages 1-17.
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Monica Gomaraschi, Maria Pia Adorni, Maciej Banach, Franco Bernini, Guido Franceschini & Laura Calabresi. 2015. High Density Lipoproteins. High Density Lipoproteins 593 615 .
Paul N. Durrington, Jonathan D. Schofield, Tarza Siahmansur & Handrean Soran. (2014) Lipoprotein (a). Current Opinion in Lipidology 25:4, pages 289-296.
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Esfandiar Heidarian, Mahmoud Rafieian-Kopaei, Abolfazle Khoshdel & Morteza Bakhshesh. (2014) Metabolic effects of berberine on liver phosphatidate phosphohydrolase in rats fed on high lipogenic diet: an additional mechanism for the hypolipidemic effects of berberine. Asian Pacific Journal of Tropical Biomedicine 4, pages S429-S435.
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Erik T. Diniz & Francisco Bandeira. 2014. Endocrinology and Diabetes. Endocrinology and Diabetes 489 502 .
U. Julius & S. Fischer. (2013) Nicotinic acid as a lipid-modifying drug – A review. Atherosclerosis Supplements 14:1, pages 7-13.
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Rigotti R. Attilio. (2012) Actualización en el manejo del colesterol hdl bajo. Revista Médica Clínica Las Condes 23:6, pages 689-692.
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