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Iloperidone, asenapine and lurasidone: a primer on their current status

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Pages 1911-1922 | Published online: 31 Jul 2012

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Sakine Atila Karaca & Duygu Yeniceli Uğur. (2018) Determination of Iloperidone in Pharmaceuticals by Validated High-Performance Liquid Chromatography. Analytical Letters 51:1-2, pages 24-32.
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Edoardo Spina & Jose de Leon. (2014) Clinically relevant interactions between newer antidepressants and second-generation antipsychotics. Expert Opinion on Drug Metabolism & Toxicology 10:5, pages 721-746.
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Frank I Tarazi & Marco A Riva. (2013) The preclinical profile of lurasidone: clinical relevance for the treatment of schizophrenia. Expert Opinion on Drug Discovery 8:10, pages 1297-1307.
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Changsu Han, Sheng-Min Wang, Masaki Kato, Soo-Jung Lee, Ashwin A Patkar, Prakash S Masand & Chi-Un Pae. (2013) Second-generation antipsychotics in the treatment of major depressive disorder: current evidence. Expert Review of Neurotherapeutics 13:7, pages 851-870.
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Frank I Tarazi & Jo C Neill. (2013) The preclinical profile of asenapine: clinical relevance for the treatment of schizophrenia and bipolar mania. Expert Opinion on Drug Discovery 8:1, pages 93-103.
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Articles from other publishers (29)

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Andrea de Bartolomeis, Mariateresa Ciccarelli, Giuseppe De Simone, Benedetta Mazza, Annarita Barone & Licia Vellucci. (2023) Canonical and Non-Canonical Antipsychotics’ Dopamine-Related Mechanisms of Present and Next Generation Molecules: A Systematic Review on Translational Highlights for Treatment Response and Treatment-Resistant Schizophrenia. International Journal of Molecular Sciences 24:6, pages 5945.
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Przemysław J. Danek & Władysława A. Daniel. (2022) The Atypical Antipsychotic Lurasidone Affects Brain but Not Liver Cytochrome P450 2D (CYP2D) Activity. A Comparison with Other Novel Neuroleptics and Significance for Drug Treatment of Schizophrenia. Cells 11:21, pages 3513.
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Jamelah S. Al-Otaibi, Y. Sheena Mary & Y. Shyma Mary. (2022) Spectroscopic analyses on an azatricycloderivative by DFT with different solvents, reactivity analysis and MD simulations. Journal of Molecular Structure 1260, pages 132845.
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Przemysław J. Danek & Władysława A. Daniel. (2021) Long-Term Treatment with Atypical Antipsychotic Iloperidone Modulates Cytochrome P450 2D (CYP2D) Expression and Activity in the Liver and Brain via Different Mechanisms. Cells 10:12, pages 3472.
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Przemysław J. Danek, Wojciech Kuban & Władysława A. Daniel. (2021) The Effect of Chronic Iloperidone Treatment on Cytochrome P450 Expression and Activity in the Rat Liver: Involvement of Neuroendocrine Mechanisms. International Journal of Molecular Sciences 22:16, pages 8447.
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Przemysław J. Danek, Ewa Bromek & Władysława A. Daniel. (2021) The Influence of Long-Term Treatment with Asenapine on Liver Cytochrome P450 Expression and Activity in the Rat. The Involvement of Different Mechanisms. Pharmaceuticals 14:7, pages 629.
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Y. Sheena Mary, Y. Shyma Mary, Stevan Armaković, Sanja J. Armaković, Magdalena Pakosinska-Parys, Rohitash Yadav & Ismail Celik. (2021) Investigation of reactive properties of an antiviral azatricyclo derivative–KDFT, MD and docking simulations. Journal of Molecular Structure 1230, pages 129937.
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Przemysław J. Danek, Jacek Wójcikowski & Władysława A. Daniel. (2020) The atypical neuroleptics iloperidone and lurasidone inhibit human cytochrome P450 enzymes in vitro. Evaluation of potential metabolic interactions. Pharmacological Reports 72:6, pages 1685-1694.
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Stephen M. Stahl. 2021. Prescriber's Guide. Prescriber's Guide 359 366 .
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Przemysław Zaręba, Anna K. Drabczyk, Jolanta Jaśkowska & Grzegorz Satała. (2020) Chemical puzzles in the search for new, flexible derivatives of lurasidone as antipsychotic drugs. Bioorganic & Medicinal Chemistry 28:10, pages 115459.
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Ewa Bromek, Marta Rysz, Anna Haduch & Władysława A. Daniel. (2019) Stimulation of 5-HT2C serotonin receptor subtype in the hypothalamic arcuate nuclei (ARC) increases the cytochrome P450 activity in the liver. Pharmacological Reports 71:6, pages 1210-1212.
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Yong Kee Choi & Frank I. Tarazi. (2018) Long-term effects of iloperidone on cerebral dopamine receptor subtypes. Synapse 72:10, pages e22039.
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Yong Kee Choi & Frank I. Tarazi. (2018) Long-Term Effects of Iloperidone on Cerebral Serotonin and Adrenoceptor Subtypes. Journal of Molecular Neuroscience 66:1, pages 59-67.
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Andrea Aguglia, Ludovico Mineo, Alessandro Rodolico, Maria S. Signorelli & Eugenio Aguglia. (2018) Asenapine in the management of impulsivity and aggressiveness in bipolar disorder and comorbid borderline personality disorder. International Clinical Psychopharmacology 33:3, pages 121-130.
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Laura Orsolini, Federica Vellante, Alessandro Valchera, Michele Fornaro, Alessandro Carano, Maurizio Pompili, Giampaolo Perna, Gianluca Serafini, Marco Di Nicola, Giovanni Martinotti, Massimo Di Giannantonio & Domenico De Berardis. 2018. Understanding Depression. Understanding Depression 257 268 .
Elisabetta Filomena Buonaguro, Felice Iasevoli, Federica Marmo, Anna Eramo, Gianmarco Latte, Camilla Avagliano, Carmine Tomasetti & Andrea de Bartolomeis. (2017) Re-arrangements of gene transcripts at glutamatergic synapses after prolonged treatments with antipsychotics: A putative link with synaptic remodeling. Progress in Neuro-Psychopharmacology and Biological Psychiatry 76, pages 29-41.
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Michele Fornaro, Domenico De Berardis, Giampaolo Perna, Marco Solmi, Nicola Veronese, Laura Orsolini, Elisabetta Filomena Buonaguro, Felice Iasevoli, Cristiano André Köhler, André Ferrer Carvalho & Andrea de Bartolomeis. (2017) Lurasidone in the Treatment of Bipolar Depression: Systematic Review of Systematic Reviews. BioMed Research International 2017, pages 1-17.
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Chris A. Oosterhof, Mostafa El Mansari, Christoffer Bundgaard & Pierre Blier. (2016) Brexpiprazole Alters Monoaminergic Systems following Repeated Administration: an in Vivo Electrophysiological Study. International Journal of Neuropsychopharmacology 19:3, pages pyv111.
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Michael Poyurovsky & Abraham Weizman. (2015) Treatment of Antipsychotic-Related Akathisia Revisited. Journal of Clinical Psychopharmacology 35:6, pages 711-714.
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James B. Lohr, Carolyn A. Eidt, Areej Abdulrazzaq Alfaraj & Mounir A. Soliman. (2015) The clinical challenges of akathisia. CNS Spectrums 20:S1, pages 1-16.
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Chris A. Oosterhof, Mostafa El Mansari & Pierre Blier. (2015) Asenapine alters the activity of monoaminergic systems following its subacute and long-term administration: An in vivo electrophysiological characterization. European Neuropsychopharmacology 25:4, pages 531-543.
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Steven G. Potkin, David B. Keator, Marilyn L. Kesler-West, Dana D. Nguyen, Theo. G. M. van Erp, Jogeshwar Mukherjee, Nikunj Shah & Adrian Preda. (2013) D 2 receptor occupancy following lurasidone treatment in patients with schizophrenia or schizoaffective disorder . CNS Spectrums 19:2, pages 176-181.
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Pierre Chue & Bogdan Neagu. 2014. A worldwide yearly survey of new data in adverse drug reactions. A worldwide yearly survey of new data in adverse drug reactions 59 84 .
Stephen M. Stahl. (2013) Role of α1 adrenergic antagonism in the mechanism of action of iloperidone: reducing extrapyramidal symptoms. CNS Spectrums 18:6, pages 285-288.
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Cynthia A. Mascareñas & Rosana Oliveira. (2013) Dynamics of drug evaluation: Formulary placement of antipsychotics. Mental Health Clinician 3:4, pages 185-187.
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Marketa Marvanova. (2013) Strategies for prevention and management of second generation antipsychotic-induced metabolic side effects. Mental Health Clinician 3:3, pages 154-161.
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