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Drug Evaluations

Dacomitinib, a new therapy for the treatment of non-small cell lung cancer

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Pages 247-253 | Published online: 07 Jan 2013

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Olgun Elicin & Mahmut Ozsahin. (2016) Current Role of Dacomitinib in Head and Neck Cancer. Expert Opinion on Investigational Drugs 25:6, pages 735-742.
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Chieh-Chien Lee, Hui-Yi Shiao, Wen-Chieh Wang & Hsing-Pang Hsieh. (2014) Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer. Expert Opinion on Investigational Drugs 23:10, pages 1333-1348.
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Robert Roskoski$suffix/text()$suffix/text(). (2013) The preclinical profile of crizotinib for the treatment of non-small-cell lung cancer and other neoplastic disorders. Expert Opinion on Drug Discovery 8:9, pages 1165-1179.
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Articles from other publishers (29)

Ibrahim A. Darwish & Hany W. Darwish. (2023) Development of novel green and high-throughput microwell spectrophotometric assay for one-step determination of dacomitinib, a recently approved potent drug for first-line treatment of metastatic non-small cell lung cancer. Sustainable Chemistry and Pharmacy 36, pages 101287.
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Zhen-Xi Niu, Ya-Tao Wang, Nan Lu, Jin-Feng Sun, Peng Nie & Piet Herdewijn. (2023) Advances of clinically approved small-molecule drugs for the treatment of non-small cell lung cancer. European Journal of Medicinal Chemistry 261, pages 115868.
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Rudradip Das, Gayatri Tambe & Amit Shard. (2023) Sulfonamides as tyrosine kinase modulators – A promising class of anticancer agents. Results in Chemistry 5, pages 100950.
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Mudasir Nabi Peerzada, Ernest Hamel, Ruoli Bai, Claudiu T. Supuran & Amir Azam. (2021) Deciphering the key heterocyclic scaffolds in targeting microtubules, kinases and carbonic anhydrases for cancer drug development. Pharmacology & Therapeutics 225, pages 107860.
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Ao Lu, Yidan Shi, Yijuan Liu, Jiahao Lin, Huarong Zhang, Yating Guo, Lisheng Li, Zeman Lin, Junling Wu, Daihan Ji & Chengdang Wang. (2021) Integrative analyses identified ion channel genes GJB2 and SCNN1B as prognostic biomarkers and therapeutic targets for lung adenocarcinoma. Lung Cancer 158, pages 29-39.
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Yuan Liang, Tiehua Zhang & Jie Zhang. (2020) Natural tyrosine kinase inhibitors acting on the epidermal growth factor receptor: Their relevance for cancer therapy. Pharmacological Research 161, pages 105164.
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Yutaro Yamamoto, Tetsuya Saita, Yuta Yamamoto, Rintaro Sogawa, Sakiko Kimura, Yutaka Narisawa, Shinya Kimura & Masashi Shin. (2019) Immunohistochemical localization of afatinib in male rat intestines and skin after its oral administration. Acta Histochemica 121:8, pages 151439.
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Mohamed W. Attwa, Adnan A. Kadi & Ali S. Abdelhameed. (2018) Characterization of reactive intermediates formation in dacomitinib metabolism and bioactivation pathways elucidation by LC-MS/MS: in vitro phase I metabolic investigation . RSC Advances 8:68, pages 38733-38744.
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Toshimitsu Yamaoka, Sojiro Kusumoto, Koichi Ando, Motoi Ohba & Tohru Ohmori. (2018) Receptor Tyrosine Kinase-Targeted Cancer Therapy. International Journal of Molecular Sciences 19:11, pages 3491.
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Lei Chen, Jing Lu, Tao Huang & Yu-Dong Cai. (2017) A computational method for the identification of candidate drugs for non-small cell lung cancer. PLOS ONE 12:8, pages e0183411.
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Jing Shi & Jun Zhu. (2015) Health Resource Utilization in Patients with Advanced Non-Small Cell Lung Cancer Receiving Chemotherapy in China. Clinical Drug Investigation 36:1, pages 77-86.
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Laura Montermini, Brian Meehan, Delphine Garnier, Wan Jin Lee, Tae Hoon Lee, Abhijit Guha, Khalid Al-Nedawi & Janusz Rak. (2015) Inhibition of Oncogenic Epidermal Growth Factor Receptor Kinase Triggers Release of Exosome-like Extracellular Vesicles and Impacts Their Phosphoprotein and DNA Content. Journal of Biological Chemistry 290:40, pages 24534-24546.
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Wei Cao, Ying Liu, Ran Zhang, Bo Zhang, Teng Wang, Xianbing Zhu, Lin Mei, Hongbo Chen, Hongling Zhang, Pinghong Ming & Laiqiang Huang. (2015) Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. Scientific Reports 5:1.
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