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Treatment options for esophageal squamous cell carcinoma

, MD PhD & , MD PhD FACS
Pages 1345-1354 | Published online: 16 May 2013

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Si Mi, Yan Qu, Xue Chen, Zhihua Wen, Pengxiang Chen & Yufeng Cheng. (2020) Radiotherapy Increases 12-LOX and CCL5 Levels in Esophageal Cancer Cells and Promotes Cancer Metastasis via THP-1-Derived Macrophages. OncoTargets and Therapy 13, pages 7719-7733.
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Ji-Xiang Cao & Yao Lu. (2019) Targeting CDC7 improves sensitivity to chemotherapy of esophageal squamous cell carcinoma. OncoTargets and Therapy 12, pages 63-74.
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Bowen Liu, Cong Wang, Pengxiang Chen, Bo Cheng & Yufeng Cheng. (2018) RACKI induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression. OncoTargets and Therapy 11, pages 211-220.
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Articles from other publishers (52)

Yang Li, Li Yang, Xiaolong Gu, Qi Wang, Gaofeng Shi, Andu Zhang, Meng Yue, Mingbo Wang & Jialiang Ren. (2023) Computed tomography radiomics identification of T1–2 and T3–4 stages of esophageal squamous cell carcinoma: two-dimensional or three-dimensional?. Abdominal Radiology.
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Sendaer Hailati, Ziruo Talihati, Kayisaier Abudurousuli, Meng yuan Han, Muhadaisi Nuer, Nawaz Khan, Nulibiya Maihemuti, Jimilihan Simayi, Dilihuma Dilimulati, Nuerbiye Nueraihemaiti & Wenting Zhou. (2023) Exploring the hub genes and mechanisms of Daphne altaica treating esophageal squamous cell carcinoma based on network pharmacology and bioinformatics analysis. Journal of Cancer Research and Clinical Oncology 149:11, pages 8467-8481.
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Iman Akhlaghipour, Negin Taghehchian, Amir Sadra Zangouei, Amirhosein Maharati, Reihaneh Alsadat Mahmoudian, Ehsan Saburi & Meysam Moghbeli. (2023) MicroRNA-377: A therapeutic and diagnostic tumor marker. International Journal of Biological Macromolecules 226, pages 1226-1235.
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Dorota Bartusik-Aebisher, Michał Osuchowski, Marta Adamczyk, Joanna Stopa, Grzegorz Cieślar, Aleksandra Kawczyk-Krupka & David Aebisher. (2022) Advancements in photodynamic therapy of esophageal cancer. Frontiers in Oncology 12.
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Dena H. Jaffe, Joseph Gricar, Marc DeCongelio & deMauri S. Mackie. (2022) A global perspective in second‐line treatment patterns for patients with advanced esophageal squamous cell carcinoma . Thoracic Cancer 13:9, pages 1240-1257.
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Zhuting Tong, Weiyang Fang, Meng Xu, YeYe Xia, Rui Wang, Yue Li, Tianqi Zha, Liang Xiao, Shuhao Pan, Huiping Chai, Lei Zhao, Hao Wang, Huaguang Pan & Xiangcun Chen. (2022) DAB2IP predicts treatment response and prognosis of ESCC patients and modulates its radiosensitivity through enhancing IR-induced activation of the ASK1-JNK pathway. Cancer Cell International 22:1.
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Fenying Lu, Weichang Chen, Tingwang Jiang, Cuie Cheng, Bin Wang, Zhiping Lu, Guojin Huang, Jiaming Qiu, Wei Wei, Ming Yang & Xia Huang. (2022) Expression profile, clinical significance and biological functions of IGF2BP2 in esophageal squamous cell carcinoma. Experimental and Therapeutic Medicine 23:4.
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Ya‐Ping Liu, Can‐Can Zheng, Yun‐Na Huang, Ming‐Liang He, Wen Wen Xu & Bin Li. (2021) Molecular mechanisms of chemo‐ and radiotherapy resistance and the potential implications for cancer treatment. MedComm 2:3, pages 315-340.
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Rukun Zang, Xiaowen Qiu, Yipeng Song & Yang Wang. (2021) Exosomes Mediated Transfer of Circ_0000337 Contributes to Cisplatin (CDDP) Resistance of Esophageal Cancer by Regulating JAK2 via miR-377-3p. Frontiers in Cell and Developmental Biology 9.
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Negar Khoshghamat, Niloufar Jafari, Mehrdad Moetamani-Ahmadi, Ghazaleh Khalili-Tanha, Mohammad-Hossein Khajavi rad, Saeed Sahebdel, Nima Khalili-Tanha, Saman Soleimanpour, Majid Khazaei, Seyed Mahdi Hassanian, Gordon A. Ferns & Amir Avan. (2021) Programmed cell death 1 as prognostic marker and therapeutic target in upper gastrointestinal cancers. Pathology - Research and Practice 220, pages 153390.
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Wei Cui, Tingting Fang, Zhaoheng Duan, Dongfang Xiang, Yanxia Wang, Mengsi Zhang, Fangzheng Zhai, Xiang Cui & Lang Yang. (2020) Dihydroartemisinin Sensitizes Esophageal Squamous Cell Carcinoma to Cisplatin by Inhibiting Sonic Hedgehog Signaling. Frontiers in Cell and Developmental Biology 8.
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Hongtao Luo, Zhen Yang, Qiuning Zhang, Lihua Shao, Shihong Wei, Ruifeng Liu, Zheng Li, Yichao Geng, Chengcheng Li & Xiaohu Wang. (2020) Carbon Ion Therapy Inhibits Esophageal Squamous Cell Carcinoma Metastasis by Upregulating STAT3 Through the JAK2/STAT3 Signaling Pathway. Frontiers in Public Health 8.
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Yanyan Cui, Dawei Yang, Wenjie Wang, Luyu Zhang, Hongtao Liu, Shanshan Ma, Wenna Guo, Minghao Yao, Kun Zhang, Wencai Li, Yanting Zhang & Fangxia Guan. (2020) Nicotinamide N‐methyltransferase decreases 5‐fluorouracil sensitivity in human esophageal squamous cell carcinoma through metabolic reprogramming and promoting the Warburg effect. Molecular Carcinogenesis 59:8, pages 940-954.
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Chengliang Yang, Sining Shen, Xiaoli Zheng, Ke Ye, Hong Ge, Yanan Sun & Yufei Lu. (2020) Long non‐coding RNA LINC00337 induces autophagy and chemoresistance to cisplatin in esophageal squamous cell carcinoma cells via upregulation of TPX2 by recruiting E2F4. The FASEB Journal 34:5, pages 6055-6069.
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Qi Shen, Bin Shang, Bin Jiang, Yu Wang, Zhou Wang & Gang Chen. (2020) Overexpression of JAB1 promotes malignant behavior and predicts poor prognosis in esophageal squamous cell carcinoma. Thoracic Cancer 11:4, pages 973-982.
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Alfred K. Lam. 2020. Esophageal Cancer. Esophageal Cancer 33 60 .
Ming Wang, Liang Wang, Xiang He, Jinhua Zhang, Zhongcheng Zhu, Mingyun Zhang & Xingde Li. (2019) lncRNA CCAT2 promotes radiotherapy resistance for human esophageal carcinoma cells via the miR‑145/p70S6K1 and p53 pathway. International Journal of Oncology.
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Yanshan Zhang, Weizuo Chen, Huijuan Wang, Tingting Pan, Yinguo Zhang & Chao Li. (2019) Upregulation of miR-519 enhances radiosensitivity of esophageal squamous cell carcinoma trough targeting PI3K/AKT/mTOR signaling pathway. Cancer Chemotherapy and Pharmacology 84:6, pages 1209-1218.
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Min Hu, Qi Zhang, Xiao‐Hui Tian, Jin‐Lin Wang, Ya‐Xuan Niu & Gang Li. (2019) lncRNA CCAT1 is a biomarker for the proliferation and drug resistance of esophageal cancer via the miR‐143/PLK1/BUBR1 axis. Molecular Carcinogenesis 58:12, pages 2207-2217.
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Qiu Hua, Xiang Gu, Xiaojun Chen, Wenbo Song, Ali Wang & Junfeng Chu. (2019) IL-8 is involved in radiation therapy resistance of esophageal squamous cell carcinoma via regulation of PCNA. Archives of Biochemistry and Biophysics 676, pages 108158.
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Hua-Zhong Huang, Yi-Fa Yin, Wen-Jun Wan, Dan Xia, Rui Wang & Xue-Min Shen. (2019) Up-regulation of microRNA-136 induces apoptosis and radiosensitivity of esophageal squamous cell carcinoma cells by inhibiting the expression of MUC1. Experimental and Molecular Pathology 110, pages 104278.
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Jian-Ge Qiu, Lin Wang, Wen-Jing Liu, Ju-Feng Wang, Er-Jiang Zhao, Feng-Mei Zhou, Xiang-Bo Ji, Li-Hong Wang, Zhong-Kun Xia, Wei Wang, Marie Chia-mi Lin, Ling-Zhi Liu, Ying-Xue Huang & Bing-Hua Jiang. (2019) Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis. Frontiers in Pharmacology 10.
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Jing-Nan Wang, Yun Che, Zu-Yang Yuan, Zhi-Liang Lu, Yuan Li, Zhi-Rong Zhang, Ning Li, Ren-Da Li, Jun Wan, Han-Dong Sun, Nan Sun, Pema-Tenzin Puno & Jie He. (2019) Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762. Toxicology and Applied Pharmacology 365, pages 71-83.
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Jian-Liang Chen, Zhi-Xiong Lin, Yun-Sheng Qin, Yu-Qi She, Yun Chen, Chen Chen, Guo-Dong Qiu, Jie-Ting Zheng, Zhong-Lin Chen & Shu-Yao Zhang. (2019) Overexpression of long noncoding RNA LINC01419 in esophageal squamous cell carcinoma and its relation to the sensitivity to 5-fluorouracil by mediating GSTP1 methylation. Therapeutic Advances in Medical Oncology 11, pages 175883591983895.
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Fei He, Haojie Wang, Yong Li, Weichao Liu, Xiang Gao, Dong Chen, Qianqian Wang & Gongning Shi. (2019) SRPX2 knockdown inhibits cell proliferation and metastasis and promotes chemosensitivity in esophageal squamous cell carcinoma. Biomedicine & Pharmacotherapy 109, pages 671-678.
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Laszló Zoltan, Robert Farkas, Andrew V. Schally, Eva Pozsgai, Andras Papp, Laura Bognár, Tamas Tornoczki, Laszlo Mangel & Szabolcs Bellyei. (2017) Possible Predictive Markers of Response to Therapy in Esophageal Squamous Cell Cancer. Pathology & Oncology Research 25:1, pages 279-288.
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Weiwei Yu & Yanmei Guo. (2018) Prognostic significance of programmed death ligand-1 immunohistochemical expression in esophageal cancer. Medicine 97:30, pages e11614.
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Jie Ying, Miaomiao Zhang, Xiaoyan Qiu & Yu Lu. (2018) The potential of herb medicines in the treatment of esophageal cancer. Biomedicine & Pharmacotherapy 103, pages 381-390.
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Rossana C. Soletti, Deborah Biasoli, Nathassya A.L.V. Rodrigues, João M.A. Delou, Renata Maciel, Vera L.A. Chagas, Rodrigo A.P. Martins, Stevens K. Rehen & Helena L. Borges. (2017) Inhibition of pRB Pathway Differentially Modulates Apoptosis in Esophageal Cancer Cells. Translational Oncology 10:5, pages 726-733.
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Liang Chen & Jingxuan Pan. (2017) Dual cyclin-dependent kinase 4/6 inhibition by PD-0332991 induces apoptosis and senescence in oesophageal squamous cell carcinoma cells. British Journal of Pharmacology 174:15, pages 2427-2443.
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Kota Momose, Makoto Yamasaki, Koji Tanaka, Yasuhiro Miyazaki, Tomoki Makino, Tsuyoshi Takahashi, Yukinori Kurokawa, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori & Yuichiro Doki. (2017) MLH1 expression predicts the response to preoperative therapy and is associated with PD-L1 expression in esophageal cancer. Oncology Letters 14:1, pages 958-964.
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Hong-Bo JiLe-Le WangXiao-Ying WangSheng-Jie YinDi ShangLi-Li SunLei Wang. (2017) Retracted: Single Nucleotide Polymorphisms in the PTPN1 Gene Are Associated with Susceptibility to Esophageal Squamous Cell Carcinoma: A Case–Control Study in Inner Mongolia, China . Genetic Testing and Molecular Biomarkers 21:5, pages 305-311.
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