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Drug Evaluations

Sodium oxybate in the treatment of alcohol dependence: from the alcohol withdrawal syndrome to the alcohol relapse prevention

, MD, , MD, , MD, , MD, , MD, , MD, Phd, , MD, , MD, Prof & , MD show all

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Emma Tay, Wing Kwan Winky Lo & Bridin Murnion. (2022) Current Insights on the Impact of Gamma-Hydroxybutyrate (GHB) Abuse. Substance Abuse and Rehabilitation 13, pages 13-23.
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A. Glahn, P. J. Proskynitopoulos, S. Bleich & T. Hillemacher. (2020) Pharmacotherapeutic management of acute alcohol withdrawal syndrome in critically Ill patients. Expert Opinion on Pharmacotherapy 21:9, pages 1083-1092.
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Giovanni Addolorato, Otto-Michael Lesch, Icro Maremmani, Henriette Walter, Felice Nava, Quentin Raffaillac & Fabio Caputo. (2020) Post-marketing and clinical safety experience with sodium oxybate for the treatment of alcohol withdrawal syndrome and maintenance of abstinence in alcohol-dependent subjects. Expert Opinion on Drug Safety 19:2, pages 159-166.
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Mariangela Antonelli, Anna Ferrulli, Luisa Sestito, Gabriele A. Vassallo, Claudia Tarli, Carolina Mosoni, Maria M. Rando, Antonio Mirijello, Antonio Gasbarrini & Giovanni Addolorato. (2018) Alcohol addiction - the safety of available approved treatment options. Expert Opinion on Drug Safety 17:2, pages 169-177.
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Articles from other publishers (32)

Juan P. Arab, Giovanni Addolorato, Philippe Mathurin & Mark R. Thursz. (2023) Alcohol-Associated Liver Disease: Integrated Management With Alcohol Use Disorder. Clinical Gastroenterology and Hepatology 21:8, pages 2124-2134.
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Filomena Fortinguerra, Andrea Pierantozzi & Francesco Trotta. (2023) The use of medications approved for alcohol use disorders in Italy. Frontiers in Public Health 11.
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Pascal Valentin Fischler, Michael Soyka, Erich Seifritz & Jochen Mutschler. (2022) Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review. Frontiers in Pharmacology 13.
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Julien Guiraud, Giovanni Addolorato, Mariangela Antonelli, Henri-Jean Aubin, Andrea de Bejczy, Amine Benyamina, Roberto Cacciaglia, Fabio Caputo, Maurice Dematteis, Anna Ferrulli, Anna E Goudriaan, Antoni Gual, Otto-Michael Lesch, Icro Maremmani, Antonio Mirijello, David J Nutt, François Paille, Pascal Perney, Roch Poulnais, Quentin Raffaillac, Jürgen Rehm, Benjamin Rolland, Claudia Rotondo, Bruno Scherrer, Nicolas Simon, Katrin Skala, Bo Söderpalm, Lorenzo Somaini, Wolfgang H Sommer, Rainer Spanagel, Gabriele A Vassallo, Henriette Walter & Wim van den Brink. (2022) Sodium oxybate for the maintenance of abstinence in alcohol-dependent patients: An international, multicenter, randomized, double-blind, placebo-controlled trial. Journal of Psychopharmacology 36:10, pages 1136-1145.
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Mariangela Antonelli, Luisa Sestito, Claudia Tarli & Giovanni Addolorato. (2022) Perspectives on the pharmacological management of alcohol use disorder: Are the approved medications effective?. European Journal of Internal Medicine 103, pages 13-22.
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Claudia Tarli, Antonio Mirijello & Giovanni Addolorato. (2022) Treating Alcohol Use Disorder in Patients with Alcohol-Associated Liver Disease: Controversies in Pharmacological Therapy. Seminars in Liver Disease 42:02, pages 138-150.
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Elizabeth M. Burnette, Steven J. Nieto, Erica N. Grodin, Lindsay R. Meredith, Brian Hurley, Karen Miotto, Artha J. Gillis & Lara A. Ray. (2022) Novel Agents for the Pharmacological Treatment of Alcohol Use Disorder. Drugs 82:3, pages 251-274.
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Otto Lesch & Henriette Walter. 2022. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 4525 4542 .
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Fabio Caputo, Mauro Cibin, Antonella Loche, Roberto De Giorgio & Giorgio Zoli. (2020) The recognition and management of protracted alcohol withdrawal may improve and modulate the pharmacological treatment of alcohol use disorder. Journal of Psychopharmacology 34:11, pages 1171-1175.
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Yun Song, Xiaobin Xue, Haibin Han, Cuiluan Li, Jia Jian, Wei Yuan & Xu Chen. (2020) Efficacy of transcutaneous electrical acupoint stimulation combined with diazepam for acute alcohol withdrawal syndrome: A double-blind randomized sham-controlled trial. Journal of International Medical Research 48:4, pages 030006052091005.
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Giovanni Addolorato, Gabriele A. Vassallo, Antonio Mirijello & Antonio Gasbarrini. (2019) Diagnosis and Management of Alcohol Use Disorder in Patients with Liver Disease: Lights and Shadows. Neurotherapeutics 17:1, pages 127-141.
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Otto-Michael Lesch, Henriette Walter, Samuel Pombo, Victor Hesselbrock & Michie Hesselbrock. 2020. Alkohol und Tabak. Alkohol und Tabak 189 270 .
Otto-Michael Lesch, Henriette Walter, Christian Wetschka, Michie N. Hesselbrock, Victor Hesselbrock & Samuel PomboOtto-Michael Lesch, Henriette Walter, Christian Wetschka, Michie N. Hesselbrock, Victor Hesselbrock & Samuel Pombo. 2020. Alcohol and Tobacco. Alcohol and Tobacco 195 270 .
Raffaele Pezzilli, Fabio Caputo, Gianni Testino, Valentino Patussi, Giovanni Greco, Livia Macciò, Maria Raffaella Rossin, Davide Mioni, Patrizia Balbinot, Claudia Gandin, Francesca Zanesini, Luca Frulloni, Sarino Aricò, Luigi C. Bottaro, Rinaldo Pellicano & Emanuele Scafato. (2019) Alcohol-related chronic exocrine pancreatic insufficiency: diagnosis and therapeutic management. A proposal for treatment by the Italian Association for the Study of the Pancreas (AISP) and the Italian Society of Alcohology (SIA). Minerva Medica 110:5.
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Fabio Caputo, Roberta Agabio, Teo Vignoli, Valentino Patussi, Tiziana Fanucchi, Paolo Cimarosti, Cristina Meneguzzi, Giovanni Greco, Raffaella Rossin, Michele Parisi, Davide Mioni, Sarino Arico’, Vincenzo Ostilio Palmieri, Valeria Zavan, Pierluigi Allosio, Patrizia Balbinot, Maria Francesca Amendola, Livia Macciò, Doda Renzetti, Emanuele Scafato & Gianni Testino. (2018) Diagnosis and treatment of acute alcohol intoxication and alcohol withdrawal syndrome: position paper of the Italian Society on Alcohol. Internal and Emergency Medicine 14:1, pages 143-160.
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M. Carmen Blanco-Gandía & Marta Rodríguez-Arias. (2018) Pharmacological treatments for opiate and alcohol addiction: A historical perspective of the last 50 years. European Journal of Pharmacology 836, pages 89-101.
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Wim van den Brink, Giovanni Addolorato, Henri-Jean Aubin, Amine Benyamina, Fabio Caputo, Maurice Dematteis, Antoni Gual, Otto-Michael Lesch, Karl Mann, Icro Maremmani, David Nutt, François Paille, Pascal Perney, Jürgen Rehm, Michel Reynaud, Nicolas Simon, Bo Söderpalm, Wolfgang H. Sommer, Henriette Walter & Rainer Spanagel. (2018) Efficacy and safety of sodium oxybate in alcohol-dependent patients with a very high drinking risk level. Addiction Biology 23:4, pages 969-986.
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Simona Guerzoni, Lanfranco Pellesi, Luigi Alberto Pini & Fabio Caputo. (2018) Drug-drug interactions in the treatment for alcohol use disorders: A comprehensive review. Pharmacological Research 133, pages 65-76.
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Camille Noélie Pujol, Cecilia Paasche, Vincent Laprevote, Benoit Trojak, Pierre Vidailhet, Elisabeth Bacon & Laurence Lalanne. (2018) Cognitive effects of labeled addictolytic medications. Progress in Neuro-Psychopharmacology and Biological Psychiatry 81, pages 306-332.
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Wolfgang Gaebel, Mathias Riesbeck, Andrea Siegert, Harald Zäske & Jürgen Zielasek. 2017. The Stigma of Mental Illness - End of the Story?. The Stigma of Mental Illness - End of the Story? 537 549 .
Michael Soyka & Jochen Mutschler. (2016) Treatment-refractory substance use disorder: Focus on alcohol, opioids, and cocaine. Progress in Neuro-Psychopharmacology and Biological Psychiatry 70, pages 148-161.
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Giovanni Addolorato, Antonio Mirijello, Pablo Barrio & Antoni Gual. (2016) Treatment of alcohol use disorders in patients with alcoholic liver disease. Journal of Hepatology 65:3, pages 618-630.
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Rama M. Kamal, Boukje A.G. Dijkstra, Anton J. Loonen & Cornelis A.J. De Jong. (2016) The Effect of Co-occurring Substance Use on Gamma-hydroxybutyric Acid Withdrawal Syndrome. Journal of Addiction Medicine 10:4, pages 229-235.
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Fabio Caputo, Angelo GI Maremmani, Giovanni Addolorato, Marco Domenicali, Giorgio Zoli, Antonio D’Amore, Icro Maremmani & Mauro Bernardi. (2016) Sodium oxybate plus nalmefene for the treatment of alcohol use disorder: A case series. Journal of Psychopharmacology 30:4, pages 402-409.
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Michel Maitre, Christian Klein & Ayikoe G. Mensah-Nyagan. (2016) Mechanisms for the Specific Properties of γ-Hydroxybutyrate in Brain. Medicinal Research Reviews 36:3, pages 363-388.
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Fabio Caputo, Teo Vignoli, Claudia Tarli, Marco Domenicali, Giorgio Zoli, Mauro Bernardi & Giovanni Addolorato. (2016) A Brief Up-Date of the Use of Sodium Oxybate for the Treatment of Alcohol Use Disorder. International Journal of Environmental Research and Public Health 13:3, pages 290.
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Stefano Gitto, Lucia Golfieri, Fabio Caputo, Silvana Grandi & Pietro Andreone. (2016) Multidisciplinary View of Alcohol Use Disorder: From a Psychiatric Illness to a Major Liver Disease. Biomolecules 6:1, pages 11.
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John M. Corkery, Barbara Loi, Hugh Claridge, Christine Goodair, Ornella Corazza, Simon Elliott & Fabrizio Schifano. (2015) Gamma hydroxybutyrate (GHB), gamma butyrolactone (GBL) and 1,4-butanediol (1,4-BD; BDO): A literature review with a focus on UK fatalities related to non-medical use. Neuroscience & Biobehavioral Reviews 53, pages 52-78.
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Antonio Mirijello, Cristina D’Angelo, Anna Ferrulli, Gabriele Vassallo, Mariangela Antonelli, Fabio Caputo, Lorenzo Leggio, Antonio Gasbarrini & Giovanni Addolorato. (2015) Identification and Management of Alcohol Withdrawal Syndrome. Drugs 75:4, pages 353-365.
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Kelly M. Youland, Ryan F. Miller, Lisa J. Mahoney, Andrew J. Borgert & Jacob D. Gundrum. (2014) Levetiracetam as Adjunctive Therapy for Acute Alcohol Withdrawal Syndrome in Hospitalized Patients. Journal of Clinical Psychopharmacology 34:6, pages 704-708.
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Fabio Caputo, Katrin Skala, Antonio Mirijello, Anna Ferrulli, Henriette Walter, Otto Lesch & Giovanni Addolorato. (2014) Sodium Oxybate in the Treatment of Alcohol Withdrawal Syndrome: A Randomized Double-Blind Comparative Study versus Oxazepam. The GATE 1 Trial. CNS Drugs 28:8, pages 743-752.
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