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Leukotriene receptor antagonists pranlukast and montelukast for treating asthma

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Inés Velázquez-Quesada, Angel J Ruiz-Moreno, Diana Casique-Aguirre, Charmina Aguirre-Alvarado, Fabiola Cortés-Mendoza, Marisol de la Fuente-Granada, Carlos García-Pérez, Sonia M Pérez-Tapia, Aliesha González-Arenas, Aldo Segura-Cabrera & Marco A Velasco-Velázquez. (2020) Pranlukast Antagonizes CD49f and Reduces Stemness in Triple-Negative Breast Cancer Cells. Drug Design, Development and Therapy 14, pages 1799-1811.
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Hiroshi Chantaphakul & Kiat Ruxrungtham. (2016) Fixed-Dose combination of the inhaled corticosteroid and long-acting beta2-agonist therapy in adults with persistent asthma. Expert Opinion on Pharmacotherapy 17:5, pages 631-642.
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Ferdinando Bruno, Verena Krauth, Seyed Mohamed Nabavi, Veronika Temml, Florinda Fratianni, Giuseppe Spaziano, Filomena Nazzaro, Fiorita Roviezzo, Jianbo Xiao, Haroon Khan, Maria Preziosa Romano, Bruno D'Agostino, Oliver Werz & Rosanna Filosa. (2022) Design and synthesis of functionalized 4-aryl-Catechol derivatives as new antiinflammtory agents with in vivo efficacy. European Journal of Medicinal Chemistry 243, pages 114788.
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Tonio Pera, Cali Loblundo & Raymond B. Penn. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology 762 802 .
Eugenia Marbach-Breitrück, Nadine Rohwer, Carmen Infante-Duarte, Silvina Romero-Suarez, Dominika Labuz, Halina Machelska, Laura Kutzner, Nils Helge Schebb, Michael Rothe, Pallu Reddanna, Karsten H. Weylandt, Lothar H. Wieler, Dagmar Heydeck & Hartmut Kuhn. (2021) Knock-In Mice Expressing a 15-Lipoxygenating Alox5 Mutant Respond Differently to Experimental Inflammation Than Reported Alox5−/− Mice. Metabolites 11:10, pages 698.
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Lars Löfgren, Gun-Britt Forsberg, Pia Davidsson, Susanna Eketjäll & Carl Whatling. (2020) Development of a highly sensitive liquid chromatography–mass spectrometry method to quantify plasma leukotriene E4 and demonstrate pharmacological suppression of endogenous 5-LO pathway activity in man. Prostaglandins & Other Lipid Mediators 150, pages 106463.
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Isaac Ruiz, Quentin Nevers, Eva Hernández, Nazim Ahnou, Rozenn Brillet, Laurent Softic, Flora Donati, Francois Berry, Sabah Hamadat, Slim Fourati, Jean-Michel Pawlotsky & Abdelhakim Ahmed-Belkacem. (2020) MK-571, a Cysteinyl Leukotriene Receptor 1 Antagonist, Inhibits Hepatitis C Virus Replication. Antimicrobial Agents and Chemotherapy 64:6.
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Stacy Gelhaus Wendell, Hao Fan & Cheng Zhang. (2019) G Protein–Coupled Receptors in Asthma Therapy: Pharmacology and Drug Action. Pharmacological Reviews 72:1, pages 1-49.
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Eugenia Marbach-BreitrückLaura KutznerMichael RotheRobert GurkeYannick SchreiberPallu ReddannaNils-Helge SchebbSabine StehlingLothar H. WielerDagmar HeydeckHartmut Kuhn. (2020) Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme. Antioxidants & Redox Signaling 32:1, pages 1-17.
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Javeed Ahmad Bhat, Nawab John Dar & Wajid Waheed Bhat. 2020. Chronic Lung Diseases. Chronic Lung Diseases 25 60 .
Igor Ivanov, Alexey B. Golovanov, Cristián Ferretti, Miquel Canyelles-Niño, Dagmar Heydeck, Sabine Stehling, José M. Lluch, Àngels González-Lafont & Hartmut Kühn. (2019) Mutations of Triad Determinants Changes the Substrate Alignment at the Catalytic Center of Human ALOX5. ACS Chemical Biology 14:12, pages 2768-2782.
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Priyanka Lohar, Manish Kumar Sharma, Amit Kumar Sahu, Rajeswari Rathod & Pinaki Sengupta. (2019) Simultaneous bioanalysis and pharmacokinetic interaction study of acebrophylline, levocetirizine and pranlukast in Sprague–Dawley rats. Biomedical Chromatography 33:12.
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Pablo de María, Gonzalo de Gonzalo & Andrés Alcántara. (2019) Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014–2019). Catalysts 9:10, pages 802.
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Xiaoyu Wu, Kai Qiao, Hong Qin, Dong Zhang, Di Gao, Zhao Yang, Zheng Fang & Kai Guo. (2019) Silver( i )-mediated oxidative C(sp 3 )–H amination of ethers with azole derivatives under mild conditions . Organic Chemistry Frontiers 6:15, pages 2672-2677.
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Haiyan Wei, Weihua Li, Zhen Jiang, Xiaoying Xi & Gongjian Qi. (2019) Clinical efficacy of montelukast sodium combined with budesonide or combined with loratadine in treating children with cough variant asthma and influence on inflammatory factors in the serum. Experimental and Therapeutic Medicine.
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Jinsong Wei, Siyuan Chen, Chengshuo Huang, Weixiong Guo, Shukai Yang, Bailin Feng & Jiaqi Chu. (2018) The cysteinyl leukotriene receptor 1 (CysLT1R) antagonist montelukast suppresses matrix metalloproteinase-13 expression induced by lipopolysaccharide. International Immunopharmacology 55, pages 193-197.
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Andrea Cignarella & Chiara Bolego. 2018. Immunopharmacology and Inflammation. Immunopharmacology and Inflammation 179 190 .
Nissar A. Darmani, Seetha Chebolu, Weixia Zhong, William D. Kim, Matthew Narlesky, Joia Adams & Fanglong Dong. (2017) The anti-asthmatic drug pranlukast suppresses the delayed-phase vomiting and reverses intracellular indices of emesis evoked by cisplatin in the least shrew (Cryptotis parva). European Journal of Pharmacology 809, pages 20-31.
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Kanchan Pyasi, Ellen Tufvesson & Subhabrata Moitra. (2016) Evaluating the role of leukotriene-modifying drugs in asthma management: Are their benefits ‘losing in translation’?. Pulmonary Pharmacology & Therapeutics 41, pages 52-59.
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Stacie J. Lampkin, Cheryl A. Maslouski, William A. Maish & Barnabas M. John. (2016) Asthma Review for Pharmacists Providing Asthma Education. The Journal of Pediatric Pharmacology and Therapeutics 21:5, pages 444-471.
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Yasuo Yonetomi, Tomohiko Sekioka, Michiaki Kadode, Tetsuya Kitamine, Akihiro Kamiya, Atsuto inoue, Takafumi Nakao, Hiroaki Nomura, Masayuki Murata, Shintaro Nakao, Fumio Nambu, Manabu Fujita, Shinji Nakade & Kazuhito Kawabata. (2015) Effects of ONO-6950, a novel dual cysteinyl leukotriene 1 and 2 receptors antagonist, in a guinea pig model of asthma. European Journal of Pharmacology 765, pages 242-248.
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Garret W. Choby & Stella Lee. (2015) Pharmacotherapy for the treatment of asthma: current treatment options and future directions. International Forum of Allergy & Rhinology 5:S1, pages S35-S40.
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Daniel Pettersen, Öjvind Davidsson & Carl Whatling. (2015) Recent advances for FLAP inhibitors. Bioorganic & Medicinal Chemistry Letters 25:13, pages 2607-2612.
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Hartmut Kuhn, Swathi Banthiya & Klaus van Leyen. (2015) Mammalian lipoxygenases and their biological relevance. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1851:4, pages 308-330.
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Aslam M.A. Mazari, Usama M. Hegazy & Bengt Mannervik. (2015) Identification of new inhibitors for human hematopoietic prostaglandin D2 synthase among FDA-approved drugs and other compounds. Chemico-Biological Interactions 229, pages 91-99.
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Malin Lemurell, Johan Ulander, Susanne Winiwarter, Anders Dahlén, Öjvind Davidsson, Hans Emtenäs, Johan Broddefalk, Marianne Swanson, Daniel Hovdal, Alleyn T. Plowright, Anna Pettersen, Marie Rydén-Landergren, Jonas Barlind, Antonio Llinas, Margareta Herslöf, Tomas Drmota, Kalle Sigfridsson, Sara Moses & Carl Whatling. (2014) Discovery of AZD6642, an Inhibitor of 5-Lipoxygenase Activating Protein (FLAP) for the Treatment of Inflammatory Diseases. Journal of Medicinal Chemistry 58:2, pages 897-911.
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Thomas Horn, Susan Adel, Ralf Schumann, Saubashya Sur, Kumar Reddy Kakularam, Aparoy Polamarasetty, Pallu Redanna, Hartmut Kuhn & Dagmar Heydeck. (2015) Evolutionary aspects of lipoxygenases and genetic diversity of human leukotriene signaling. Progress in Lipid Research 57, pages 13-39.
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Susan Adel, Kumar Reddy Kakularam, Thomas Horn, Pallu Reddanna, Hartmut Kuhn & Dagmar Heydeck. (2015) Leukotriene signaling in the extinct human subspecies Homo denisovan and Homo neanderthalensis. Structural and functional comparison with Homo sapiens. Archives of Biochemistry and Biophysics 565, pages 17-24.
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M. Fayon, V. Feret, G. Sagbo & S. Debelleix. (2014) Alternatives à la corticothérapie inhalée dans le traitement de l’asthme de l’enfant : les anti-leucotriènes. Revue Française d'Allergologie 54:3, pages 92-95.
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ferdinando bruno, Verena Krauth, florinda Fratianni, giuseppe spaziano, Filomena Nazzaro, Fiorentina Roviezzo, Seyed Mohammad Nabavi, Haroon Khan, Maria Preziosa Romano, Bruno D'Agostino, Oliver Werz & rosanna filosa. (2022) Design and Synthesis of Functionalized4-Aryl-Catechol Derivatives as New Anti-Inflammatory Agents with In Vivo Efficacy PART I. SSRN Electronic Journal.
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