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Drug Evaluations

Icotinib: activity and clinical application in Chinese patients with lung cancer

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Ya-Nan Wang, Zhi-Qiang Cai, Chen-Kang Zhao, Bo-Wang, Liang-Liang Chi, Wei-Tao Qin, Li-Hua Wu & De-Qiang Zheng. (2023) Novel 4-arylaminoquinazoline derivatives: design, synthesis, crystal structure and biological evaluation as potent antitumor agents. Molecular Crystals and Liquid Crystals 759:1, pages 80-98.
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Articles from other publishers (16)

Qi Zhou, Feng Ye, Zhize Ye, Nanyong Gao, Qihui Kong, Xiaoqin Hu, Jianchang Qian & Bin Wu. (2023) The effect of icotinib or apatinib on the pharmacokinetic profile of oxycodone in rats and the underlying mechanism. PeerJ 11, pages e16601.
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Bo Li, Wenqian Chen, Fang Liu, Xiaoxue Wang, Wei Qin, Shu Li, Hongkai Lu, Guan Wang, Xiaoyang Liu, Pengmei Li, Xianbo Zuo, Xianglin Zhang, Lihong Liu & Meng Yang. (2023) A fully validated method for simultaneous determination of icotinib, osimertinib, gefitinib and O-desmethyl gefitinib in human plasma using UPLC-MS/MS for therapeutic drug monitoring. Journal of Pharmaceutical and Biomedical Analysis 236, pages 115697.
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E.J. Corey & Yong‐Jin Wu. 2023. Molecules Engineered Against Oncogenic Proteins and Cancer. Molecules Engineered Against Oncogenic Proteins and Cancer 59 96 .
Robert Roskoski Jr.. (2023) Small molecule protein kinase inhibitors approved by regulatory agencies outside of the United States. Pharmacological Research 194, pages 106847.
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Poojarani Panda, Henu Kumar Verma & Lakkakula V. K. S. Bhaskar. (2023) Precision Medicine Revolutionizing Esophageal Cancer Treatment: Surmounting Hurdles and Enhancing Therapeutic Efficacy through Targeted Drug Therapies. Onco 3:3, pages 127-146.
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Junhong Ye, Jifu Li & Ping Zhao. (2023) The Silkworm Carboxypeptidase Inhibitor Prevents Gastric Cancer Cells’ Proliferation through the EGF/EGFR Signaling Pathway. International Journal of Molecular Sciences 24:2, pages 1078.
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Yuankai Shi. (2023) Landscape of the clinical development of China innovative anti-lung cancer drugs. Cancer Pathogenesis and Therapy 1:1, pages 67-75.
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子繁 王. (2022) Study on First-Generation TKIs in the Treatment of Patients with Unresectable EGFR-Mutation-Positive Non-Small-Cell Lung Cancer. Advances in Clinical Medicine 12:02, pages 761-770.
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Xueli Tian, Tingxuan Gu, Mee-Hyun Lee & Zigang Dong. (2022) Challenge and countermeasures for EGFR targeted therapy in non-small cell lung cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877:1, pages 188645.
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Hui-Ying Li, Yu Xie, Ting-Ting Yu, Yong-Juan Lin & Zhen-Yu Yin. (2020) Durable response to pulsatile icotinib for central nervous system metastases from EGFR -mutated non-small cell lung cancer: A case report . World Journal of Clinical Cases 8:2, pages 370-376.
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Ka Wu, Chao Guo & Rong Li. (2019) Clinical characterization of icotinib-induced chemoresistance in erlotinib-treated lung adenocarcinoma patient with EGFR mutations. Medicine 98:18, pages e15489.
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Ning-Ning Yang, Fei Xiong, Qing He & Yong-Song Guan. (2018) Achievable complete remission of advanced non-small-cell lung cancer: Case report and review of the literature. World Journal of Clinical Cases 6:7, pages 150-155.
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Pinghui Xia, Jinlin Cao, Xiayi Lv, Luming Wang, Wang Lv & Jian Hu. (2018) Combination therapy of apatinib with icotinib for primary acquired icotinib resistance in patients with advanced pulmonary adenocarcinoma with EGFR mutation. Thoracic Cancer 9:5, pages 656-661.
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Ning Tang, Qianqian Zhang, Shu Fang, Xiao Han & Zhehai Wang. (2016) Anti-tumor activity of high-dose EGFR tyrosine kinase inhibitor and sequential docetaxel in wild type EGFR non-small cell lung cancer cell nude mouse xenografts. Oncotarget 8:6, pages 9134-9143.
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XiaoMei Zhuang, TianHong Zhang, SiJia Yue, Juan Wang, Huan Luo, YunXia Zhang, Zheng Li, JinJing Che, HaiYing Yang, Hua Li, MingShe Zhu & Chuang Lu. (2016) Allosteric activation of midazolam CYP3A5 hydroxylase activity by icotinib – Enhancement by ketoconazole. Biochemical Pharmacology 121, pages 67-77.
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Jing Zhao, Hong Shen, Han-Guang Hu & Jian-Jin Huang. (2015) Icotinib plus gemcitabine for metastatic pancreatic cancer: A case report. World Journal of Gastroenterology 21:11, pages 3441-3446.
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