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Molecular abnormalities of the B cell in systemic lupus erythematosus are candidates for functional inhibition treatments

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Alessia Leone, Savino Sciascia, Ameer Kamal & Munther Khamashta. (2015) Biologicals for the treatment of systemic lupus erythematosus: current status and emerging therapies. Expert Review of Clinical Immunology 11:1, pages 109-116.
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Yi Zhang, FengQi Zhang, YiNi Gao, MeiJiao Wang, Yan Gao, HaiChang Li, Jing Sun, ChengPing Wen & ZhiJun Xie. (2022) Triptolide in the treatment of systemic lupus erythematosus - regulatory effects on miR-146a in B cell TLR7 signaling pathway in mice. Frontiers in Pharmacology 13.
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Yosuke Kunishita, Ryusuke Yoshimi, Reikou Kamiyama, Daiga Kishimoto, Takaaki Komiya, Natsuki Sakurai, Yumiko Sugiyama, Kaoru Takase-Minegishi, Yohei Kirino, Shouhei Nagaoka & Hideaki Nakajima. (2021) Anti-TRIM21 antibody is associated with aberrant B-cell function and type I interferon production in systemic lupus erythematosus. Lupus 30:13, pages 2054-2065.
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Ina Georg, Alejandro Díaz-Barreiro, Maria Morell, Angel L. Pey & Marta E. Alarcón-Riquelme. (2019) BANK1 interacts with TRAF6 and MyD88 in innate immune signaling in B cells. Cellular & Molecular Immunology 17:9, pages 954-965.
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Yosuke Kunishita, Ryusuke Yoshimi, Reikou Kamiyama, Daiga Kishimoto, Koji Yoshida, Eijin Hashimoto, Takaaki Komiya, Natsuki Sakurai, Yumiko Sugiyama, Yohei Kirino, Keiko Ozato & Hideaki Nakajima. (2020) TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis. Frontiers in Immunology 11.
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Chenqiong Wang, Bingxia Ming, Xuefen Wu, Tong Wu, Shaozhe Cai, Peng Hu, Jungen Tang, Zheng Tan, Chaohong Liu, Jixin Zhong, Fang Zheng & Lingli Dong. (2019) Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response. EBioMedicine 45, pages 578-587.
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Daniel Ramsköld, Ioannis Parodis, Tadepally Lakshmikanth, Natalie Sippl, Mohsen Khademi, Yang Chen, Agneta Zickert, Jaromír Mikeš, Adnane Achour, Khaled Amara, Fredrik Piehl, Petter Brodin, Iva Gunnarsson & Vivianne Malmström. (2019) B cell alterations during BAFF inhibition with belimumab in SLE. EBioMedicine 40, pages 517-527.
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Vaishali R. Moulton, Abel Suarez-Fueyo, Esra Meidan, Hao Li, Masayuki Mizui & George C. Tsokos. (2017) Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective. Trends in Molecular Medicine 23:7, pages 615-635.
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Caroline Gordon, David Wofsy, Stephen Wax, Yong Li, Claudia Pena Rossi & David Isenberg. (2016) Post Hoc Analysis of the Phase II/III APRIL‐SLE Study: Association Between Response to Atacicept and Serum Biomarkers Including BLyS and APRIL. Arthritis & Rheumatology 69:1, pages 122-130.
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William Hoffman, Fadi G. Lakkis & Geetha Chalasani. (2016) B Cells, Antibodies, and More. Clinical Journal of the American Society of Nephrology 11:1, pages 137-154.
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Terry King-Wing Ma, Stephen P. McAdoo & Frederick Wai-Keung Tam. (2016) Spleen Tyrosine Kinase: A Crucial Player and Potential Therapeutic Target in Renal Disease. Nephron 133:4, pages 261-269.
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LiDan Zhao, YanXia Ye & Xuan Zhang. (2015) B cells biology in systemic lupus erythematosus—from bench to bedside. Science China Life Sciences 58:11, pages 1111-1125.
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