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Expert Opinion on Pharmacotherapy Volume 16, 2015 - Issue 18
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Drug Evaluations

Empagliflozin and linagliptin combination therapy for treatment of patients with type 2 diabetes mellitus

C TriplittDepartment of Medicine, Diabetes Division, University of Texas Health Science Center and Texas Diabetes Institute, San Antonio, TX78229, USA
,
C Solis-HerreraDepartment of Medicine, Diabetes Division, University of Texas Health Science Center and Texas Diabetes Institute, San Antonio, TX78229, USA
,
E CersosimoDepartment of Medicine, Diabetes Division, University of Texas Health Science Center and Texas Diabetes Institute, San Antonio, TX78229, USA
,
M Abdul-GhaniDepartment of Medicine, Diabetes Division, University of Texas Health Science Center and Texas Diabetes Institute, San Antonio, TX78229, USA
&
Ralph A DefronzoDepartment of Medicine, Diabetes Division, University of Texas Health Science Center and Texas Diabetes Institute, San Antonio, TX78229, USACorrespondence[email protected]
Pages 2819-2833 | Published online: 19 Nov 2015

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André J. Scheen. (2016) DPP-4 inhibitor plus SGLT-2 inhibitor as combination therapy for type 2 diabetes: from rationale to clinical aspects. Expert Opinion on Drug Metabolism & Toxicology 12:12, pages 1407-1417.
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Articles from other publishers (15)

Anil Kumar Goud Thallapalli & Ram Mohan Manda. (2023) Development and validation of Empagliflozin and Linagliptin simultaneous estimation in rat plasma using freezing lipid precipitation and SCX-SPE assisted HPLC–MS/MS method and its application in pharmacokinetic studies. Analytical Sciences.
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Hira Shakoor, Haneen Hussein, Nour Al-Hassan, Mouza Alketbi, Jaleel Kizhakkayil & Carine Platat. (2023) The Muscle-Conditioned Medium Containing Protocatechuic Acid Improves Insulin Resistance by Modulating Muscle Communication with Liver and Adipose Tissue. International Journal of Molecular Sciences 24:11, pages 9490.
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Manoj Chadha, Ashok Kumar Das, Prasun Deb, Kalyan Kumar Gangopadhyay, Shashank Joshi, Jothydev Kesavadev, Rajiv Kovil, Surender Kumar, Anoop Misra & Viswanathan Mohan. (2022) Expert Opinion: Optimum Clinical Approach to Combination-Use of SGLT2i + DPP4i in the Indian Diabetes Setting. Diabetes Therapy 13:5, pages 1097-1114.
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Maria Laura Ricardo-Silgado, Alison McRae & Andres Acosta. (2021) Role of enteroendocrine hormones in appetite and glycemia. Obesity Medicine 23, pages 100332.
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Md. Wasim Bari, Md. Monirul Islam, Mahbuba Khatun, Mst Julia Sultana, Rabbi Ahmed, Ariful Islam, Md. Ismail Hossain, Md. Matiar Rahman & Mohammad Amirul Islam. (2020) Antidiabetic effect of Wedelia chinensis leaf extract in alloxan induced Swiss albino diabetic mice. Clinical Phytoscience 6:1.
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Mehdi Taib, Yassine Rezzak, Lahboub Bouyazza & Badiaa Lyoussi. (2020) Medicinal Uses, Phytochemistry, and Pharmacological Activities of Quercus Species . Evidence-Based Complementary and Alternative Medicine 2020, pages 1-20.
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Elisangela Aparecida Nazario Franco, Ana Sanches-Silva, Regiane Ribeiro-Santos & Nathália Ramos de Melo. (2020) Psyllium (Plantago ovata Forsk): From evidence of health benefits to its food application. Trends in Food Science & Technology 96, pages 166-175.
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Gita Chawla & Krishna Kr Chaudhary. (2019) A complete review of empagliflozin: Most specific and potent SGLT2 inhibitor used for the treatment of type 2 diabetes mellitus. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 13:3, pages 2001-2008.
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Priyanka A. Shah, Pranav S. Shrivastav & Archana George. (2019) Mixed-mode solid phase extraction combined with LC-MS/MS for determination of empagliflozin and linagliptin in human plasma. Microchemical Journal 145, pages 523-531.
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Annayya R. Aroor, Camila Manrique-Acevedo & Vincent G. DeMarco. (2018) The role of dipeptidylpeptidase-4 inhibitors in management of cardiovascular disease in diabetes; focus on linagliptin. Cardiovascular Diabetology 17:1.
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André J. Scheen. (2016) Pharmacokinetic Characteristics and Clinical Efficacy of an SGLT2 Inhibitor Plus DPP-4 Inhibitor Combination Therapy in Type 2 Diabetes. Clinical Pharmacokinetics 56:7, pages 703-718.
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Annette Boles, Ramesh Kandimalla & P. Hemachandra Reddy. (2017) Dynamics of diabetes and obesity: Epidemiological perspective. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863:5, pages 1026-1036.
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Hao Liu, Yun Hu, Feng-fei Li, Bing-li Liu, Xiao-fei Su & Jian-hua Ma. (2016) Blood Glucagon Levels Predict the Hemoglobin A1c Response to Saxagliptin in Patients with Type 2 Diabetes Inadequately Controlled with Metformin. Diabetes Therapy 7:4, pages 743-753.
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Heidi Storgaard, Lise L. Gluud, Cathy Bennett, Magnus F. Grøndahl, Mikkel B. Christensen, Filip K. Knop & Tina Vilsbøll. (2016) Benefits and Harms of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis. PLOS ONE 11:11, pages e0166125.
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R. A. DeFronzo, R. Chilton, L. Norton, G. Clarke, R. E. J. Ryder & M. Abdul‐Ghani. (2016) Revitalization of pioglitazone: the optimum agent to be combined with a sodium‐glucose co‐transporter‐2 inhibitor. Diabetes, Obesity and Metabolism 18:5, pages 454-462.
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