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Expert Opinion on Pharmacotherapy Volume 17, 2016 - Issue 1
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Current treatment options for hereditary angioedema due to C1 inhibitor deficiency

Maddalena Alessandra WuDepartment of Biomedical and Clinical Sciences “Luigi Sacco”, Luigi Sacco Hospital, University of Milan, Milan, Italy
,
Andrea ZanichelliDepartment of Biomedical and Clinical Sciences “Luigi Sacco”, Luigi Sacco Hospital, University of Milan, Milan, Italy
,
Marta MansiDepartment of Biomedical and Clinical Sciences “Luigi Sacco”, Luigi Sacco Hospital, University of Milan, Milan, Italy
&
Marco CicardiDepartment of Biomedical and Clinical Sciences “Luigi Sacco”, Luigi Sacco Hospital, University of Milan, Milan, ItalyCorrespondence[email protected]
Pages 27-40 | Published online: 29 Oct 2015

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Andrea Zanichelli, Vincenzo Montinaro, Massimo Triggiani, Francesco Arcoleo, Debora Visigalli & Mauro Cancian. (2022) Emerging drugs for the treatment of hereditary angioedema due to C1-inhibitor deficiency. Expert Opinion on Emerging Drugs 27:2, pages 103-110.
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Anna Valerieva, Sonia Caccia & Marco Cicardi. (2018) Recombinant human C1 esterase inhibitor (Conestat alfa) for prophylaxis to prevent attacks in adult and adolescent patients with hereditary angioedema. Expert Review of Clinical Immunology 14:9, pages 707-718.
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Articles from other publishers (15)

Siobhán Hayes, Colm Farrell, Anurag Relan & John Anderson. (2021) Population pharmacokinetics of recombinant human C1 esterase inhibitor in children with hereditary angioedema. Annals of Allergy, Asthma & Immunology 126:6, pages 707-712.
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Anne Lesage, Christoph Gibson, François Marceau, Horst-Dieter Ambrosi, Jörn Saupe, Werner Katzer, Brigitte Loenders, Xavier Charest-Morin & Jochen Knolle. (2020) In Vitro Pharmacological Profile of a New Small Molecule Bradykinin B2 Receptor Antagonist. Frontiers in Pharmacology 11.
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Maddalena Alessandra Wu, Riccardo Colombo, Gian Marco Podda & Marco Cicardi. (2019) Handling shock in idiopathic systemic capillary leak syndrome (Clarkson’s disease): less is more. Internal and Emergency Medicine 14:5, pages 723-730.
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Ting Qiu, Maria J. Chiuchiolo, Adele S. Whaley, Anthony R. Russo, Dolan Sondhi, Stephen M. Kaminsky, Ronald G. Crystal & Odelya E. Pagovich. (2019) Gene therapy for C1 esterase inhibitor deficiency in a Murine Model of Hereditary angioedema. Allergy.
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Anna Valerieva, Marco Cicardi, James Baraniuk & Maria Staevska. (2018) The physician and hereditary angioedema friend or foe: 62-year diagnostic delay and iatrogenic procedures. Allergy, Asthma & Clinical Immunology 14:1.
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Carlo Federici, Francesca Perego, Ludovica Borsoi, Valentina Crosta, Andrea Zanichelli, Antonio Gidaro, Rosanna Tarricone & Marco Cicardi. (2018) Costs and effects of on-demand treatment of hereditary angioedema in Italy: a prospective cohort study of 167 patients. BMJ Open 8:7, pages e022291.
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Marco Cicardi & Bruce L. Zuraw. (2018) Angioedema Due to Bradykinin Dysregulation. The Journal of Allergy and Clinical Immunology: In Practice 6:4, pages 1132-1141.
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Mignon van den Elzen, M. F. C. L. Go, A. C. Knulst, M. A. Blankestijn, H. van Os-Medendorp & H. G. Otten. (2016) Efficacy of Treatment of Non-hereditary Angioedema. Clinical Reviews in Allergy & Immunology 54:3, pages 412-431.
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Daniel P. TeufelGavin BennettHelen HarrisonKaterine van RietschotenSilvia PavanCatherine StaceFrançois Le Floch, Tine Van Bergen, Elke Vermassen, Philippe Barbeaux, Tjing-Tjing Hu, Jean H. M. Feyen & Marc Vanhove. (2018) Stable and Long-Lasting, Novel Bicyclic Peptide Plasma Kallikrein Inhibitors for the Treatment of Diabetic Macular Edema. Journal of Medicinal Chemistry 61:7, pages 2823-2836.
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N.T.M.L. Fragnan, A.L.N. Tolentino, G.B. Borba, A.C. Oliveira, J.A. Simões, S.M.U. Palma, R.N. Constantino-Silva & A.S. Grumach. (2018) Hereditary angioedema with C1 inhibitor (C1-INH) deficit: the strength of recognition (51 cases). Brazilian Journal of Medical and Biological Research 51:12.
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Scott R. Barnum. (2017) Complement: A primer for the coming therapeutic revolution. Pharmacology & Therapeutics 172, pages 63-72.
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Lakshmi C. WijeyewickremaEmilie LameignereLilian HorRenee C. DuncanToshikazu ShibaRichard J. Travers, Piyushkumar R. KapoparaVictor LeiStephanie A. Smith, Hugh Kim, James H. Morrissey, Robert N. PikeEdward M. Conway. (2016) Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor. Blood 128:13, pages 1766-1776.
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Daniel Ricklin, Edimara S. Reis & John D. Lambris. (2016) Complement in disease: a defence system turning offensive. Nature Reviews Nephrology 12:7, pages 383-401.
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Daniel Ricklin & John D. Lambris. (2016) New milestones ahead in complement-targeted therapy. Seminars in Immunology 28:3, pages 208-222.
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Berhane Ghebrehiwet. (2016) The complement system: an evolution in progress. F1000Research 5, pages 2840.
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