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Rifaximin and eluxadoline — newly approved treatments for diarrhea-predominant irritable bowel syndrome: what is their role in clinical practice alongside alosetron?

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Pages 311-322 | Received 09 Apr 2015, Accepted 05 Nov 2015, Published online: 08 Dec 2015

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Kevin W. Olden, William D. Chey, Reshma Shringarpure, Jean Paul Nicandro, Emil Chuang & David L. Earnest. (2019) Alosetron versus traditional pharmacotherapy in clinical practice: effects on resource use, health-related quality of life, safety and symptom improvement in women with severe diarrhea-predominant irritable bowel syndrome. Current Medical Research and Opinion 35:3, pages 461-472.
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Konstantinos C Fragkos. (2017) Spotlight on eluxadoline for the treatment of patients with irritable bowel syndrome with diarrhea. Clinical and Experimental Gastroenterology 10, pages 229-240.
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Articles from other publishers (11)

Michael Camilleri & Saam Dilmaghani. (2023) Update on treatment of abdominal pain in irritable bowel syndrome: A narrative review. Pharmacology & Therapeutics 245, pages 108400.
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Christopher J Black, Nicholas E Burr, Michael Camilleri, David L Earnest, Eamonn MM Quigley, Paul Moayyedi, Lesley A Houghton & Alexander C Ford. (2020) Efficacy of pharmacological therapies in patients with IBS with diarrhoea or mixed stool pattern: systematic review and network meta-analysis. Gut 69:1, pages 74-82.
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Christopher N Andrews & Marc Bradette. (2019) Diarrhea-Predominant Irritable Bowel Syndrome: Medical Management Update. Journal of the Canadian Association of Gastroenterology.
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Yi Zheng, Samuel Obeng, Huiqun Wang, David L. Stevens, Essie Komla, Dana E. Selley, William L. Dewey, Hamid I. Akbarali & Yan Zhang. (2018) Methylation Products of 6β- N -Heterocyclic Substituted Naltrexamine Derivatives as Potential Peripheral Opioid Receptor Modulators . ACS Chemical Neuroscience 9:12, pages 3028-3037.
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Brian E. Lacy, Jean Paul Nicandro, Emil Chuang & David L. Earnest. (2018) Alosetron use in clinical practice: significant improvement in irritable bowel syndrome symptoms evaluated using the US Food and Drug Administration composite endpoint. Therapeutic Advances in Gastroenterology 11, pages 175628481877167.
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Thomas C. Marbury, Jolene Kay Berg, Leonard S. Dove & Paul S. Covington. (2017) Effect of Hepatic Impairment on Eluxadoline Pharmacokinetics. The Journal of Clinical Pharmacology 57:11, pages 1454-1459.
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Sherry Levio & Brooks D. Cash. (2017) The place of eluxadoline in the management of irritable bowel syndrome with diarrhea. Therapeutic Advances in Gastroenterology 10:9, pages 715-725.
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J Tack, K Schumacher, G Tonini, S Scartoni, A Capriati & C A Maggi. (2017) The neurokinin-2 receptor antagonist ibodutant improves overall symptoms, abdominal pain and stool pattern in female patients in a phase II study of diarrhoea-predominant IBS. Gut 66:8, pages 1403-1413.
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Longtu Chen, Sheikh J. Ilham & Bin Feng. (2017) Pharmacological Approach for Managing Pain in Irritable Bowel Syndrome: A Review Article. Anesthesiology and Pain Medicine 7:2.
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W. E. Whitehead, K. Duffy, J. Sharpe, T. Nabata & M. Bruce. (2017) Randomised clinical trial: exploratory phase 2 study of ONO-2952 in diarrhoea-predominant irritable bowel syndrome. Alimentary Pharmacology & Therapeutics 45:1, pages 14-26.
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Giuseppe Esposito, Nicola Nobile, Stefano Gigli, Luisa Seguella, Marcella Pesce, Alessandra d’Alessandro, Eugenia Bruzzese, Elena Capoccia, Luca Steardo, Rosario Cuomo & Giovanni Sarnelli. (2016) Rifaximin Improves Clostridium difficile Toxin A-Induced Toxicity in Caco-2 Cells by the PXR-Dependent TLR4/MyD88/NF-κB Pathway. Frontiers in Pharmacology 7.
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