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Review

The search for the ideal SERM

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Pages 681-691 | Published online: 25 Feb 2005

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Jack Feehan, Ahmed Al Saedi & Gustavo Duque. (2019) Targeting fundamental aging mechanisms to treat osteoporosis. Expert Opinion on Therapeutic Targets 23:12, pages 1031-1039.
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Daniel S Sem. (2004) Chemical proteomics from a nuclear magnetic resonance spectroscopy perspective. Expert Review of Proteomics 1:2, pages 165-178.
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Zhenlin Liang, Lijuan Liu, Yanyu Zhou, Wukun Liu & Yunlong Lu. (2023) Research Progress on Bioactive Metal Complexes against ER-Positive Advanced Breast Cancer. Journal of Medicinal Chemistry 66:4, pages 2235-2256.
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S. Silverman & C. Christiansen. (2012) Individualizing osteoporosis therapy. Osteoporosis International 23:3, pages 797-809.
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Barry S. Komm, Fay Vlasseros, Rana Samadfam, Luc Chouinard & Susan Y. Smith. (2011) Skeletal effects of bazedoxifene paired with conjugated estrogens in ovariectomized rats. Bone 49:3, pages 376-386.
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Harry K Genant. (2011) Bazedoxifene: a new selective estrogen receptor modulator for postmenopausal osteoporosis. Menopause International 17:2, pages 44-49.
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Gloria Bachmann, Uel Crosby, Robert A. Feldman, Sheila Ronkin & Ginger D. Constantine. (2011) Effects of bazedoxifene in nonflushing postmenopausal women. Menopause 18:5, pages 508-514.
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Akira Itabashi, Kousei Yoh, Arkadi A Chines, Takami Miki, Masahiko Takada, Hiroshi Sato, Itsuo Gorai, Toshitsugu Sugimoto, Hideki Mizunuma, Hiroshi Ochi, Ginger D Constantine & Hiroaki Ohta. (2011) Effects of bazedoxifene on bone mineral density, bone turnover, and safety in postmenopausal japanese women with osteoporosis. Journal of Bone and Mineral Research 26:3, pages 519-529.
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T. J. de Villiers, A. A. Chines, S. Palacios, P. Lips, A. Z. Sawicki, A. B. Levine, C. Codreanu, N. Kelepouris & J. P. Brown. (2010) Safety and tolerability of bazedoxifene in postmenopausal women with osteoporosis: results of a 5-year, randomized, placebo-controlled phase 3 trial. Osteoporosis International 22:2, pages 567-576.
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L. Xu, K.-S. Tsai, G. S. Kim, Y. Wu, P. Vincendon, A. A. Chines & G. D. Constantine. (2010) Efficacy and safety of bazedoxifene in postmenopausal Asian women. Osteoporosis International 22:2, pages 559-565.
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J. Christopher Gallagher & Jeffrey P. Levine. (2011) Preventing osteoporosis in symptomatic postmenopausal women. Menopause 18:1, pages 109-118.
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Claus Christiansen, Charles H ChesnutIIIIII, Jonathan D Adachi, Jacques P Brown, César E Fernandes, Annie WC Kung, Santiago Palacios, Amy B Levine, Arkadi A Chines & Ginger D Constantine. (2010) Safety of bazedoxifene in a randomized, double-blind, placebo- and active-controlled phase 3 study of postmenopausal women with osteoporosis. BMC Musculoskeletal Disorders 11:1.
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Toine F.H. Bovee, Mario Thevis, Astrid R.M. Hamers, Ad A.C.M. Peijnenburg, Michel W.F. Nielen & Willem G.E.J. Schoonen. (2010) SERMs and SARMs: Detection of their activities with yeast based bioassays. The Journal of Steroid Biochemistry and Molecular Biology 118:1-2, pages 85-92.
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David F Archer. 2008. Endometrium, The. Endometrium, The 761 770 .
Sabine Rehm, Henk A. Solleveld, Samm T. Portelli & Patrick J. Wier. (2007) Histologic changes in ovary, uterus, vagina, and mammary gland of mature beagle dogs treated with the SERM idoxifene. Birth Defects Research Part B: Developmental and Reproductive Toxicology 80:3, pages 225-232.
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Tara E. Sutherland, Michael Schuliga, Trudi Harris, Bedrich L. Eckhardt, Robin L. Anderson, Lilly Quan & Alastair G. Stewart. (2005) 2-Methoxyestradiol Is an Estrogen Receptor Agonist That Supports Tumor Growth in Murine Xenograft Models of Breast Cancer. Clinical Cancer Research 11:5, pages 1722-1732.
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C K Osborne, A Wakeling & R I Nicholson. (2004) Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. British Journal of Cancer 90:S1, pages S2-S6.
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Chang Bai, Azriel Schmidt & Leonard P. Freedman. (2003) Steroid Hormone Receptors and Drug Discovery: Therapeutic Opportunities and Assay Designs. ASSAY and Drug Development Technologies 1:6, pages 843-852.
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Israel Yoles, Yariv Yogev, Yair Frenkel, Ravit Nahum, Michael Hirsch & Boris Kaplan. (2003) Tofupill/Femarelle (DT56a): a new phyto-selective estrogen receptor modulator-like substance for the treatment of postmenopausal bone loss. Menopause 10:6, pages 522-525.
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D. Somjen & I. Yoles. (2014) DT56a stimulates creatine kinase specific activity in vascular tissues of rats. Journal of Endocrinological Investigation 26:10, pages 966-971.
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