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Eptifibatide: a potent inhibitor of the platelet receptor integrin glycoprotein IIb/IIIa

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Pages 1199-1210 | Published online: 25 Feb 2005

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Georg Gelbenegger & Bernd Jilma. (2022) Clinical pharmacology of antiplatelet drugs. Expert Review of Clinical Pharmacology 15:10, pages 1177-1197.
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Taylor B. Smallwood & Richard J. Clark. (2021) Advances in venom peptide drug discovery: where are we at and where are we heading?. Expert Opinion on Drug Discovery 16:10, pages 1163-1173.
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Glenn F King. (2011) Venoms as a platform for human drugs: translating toxins into therapeutics. Expert Opinion on Biological Therapy 11:11, pages 1469-1484.
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Ana Novo de Oliveira, Andreimar Martins Soares & Saulo Luís Da Silva. (2023) Why to Study Peptides from Venomous and Poisonous Animals?. International Journal of Peptide Research and Therapeutics 29:5.
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Jasmin Gattringer, Christian W. Gruber & Roland Hellinger. (2023) Peptide modulators of cell migration: Overview, applications and future development. Drug Discovery Today 28:5, pages 103554.
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Danique L. van den Kerkhof, Magdolna Nagy, Kanin Wichapong, Sanne L.N. Brouns, Dennis P.L. Suylen, Tilman M. Hackeng & I. Dijkgraaf. (2022) Unraveling the role of the homoarginine residue in antiplatelet drug eptifibatide in binding to the αIIbβ3 integrin receptor. Thrombosis Research 217, pages 96-103.
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Asirwatham Pushpa Arokia Rani & Marie Serena McConnell. 2022. Snake Venom and Ecology. Snake Venom and Ecology.
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Fatah Chérifi & Fatima Laraba-Djebari. (2021) Bioactive Molecules Derived from Snake Venoms with Therapeutic Potential for the Treatment of Thrombo-Cardiovascular Disorders Associated with COVID-19. The Protein Journal 40:6, pages 799-841.
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Karla de Castro Figueiredo Bordon, Camila Takeno Cologna, Elisa Corrêa Fornari-Baldo, Ernesto Lopes Pinheiro-Júnior, Felipe Augusto Cerni, Fernanda Gobbi Amorim, Fernando Antonio Pino Anjolette, Francielle Almeida Cordeiro, Gisele Adriano Wiezel, Iara Aimê Cardoso, Isabela Gobbo Ferreira, Isadora Sousa de Oliveira, Johara Boldrini-França, Manuela Berto Pucca, Mateus Amaral Baldo & Eliane Candiani Arantes. (2020) From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery. Frontiers in Pharmacology 11.
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Tomasz Brzoska, Ravi Vats, Margaret F. Bennewitz, Egemen Tutuncuoglu, Simon C. Watkins, Margaret V. Ragni, Matthew D. Neal, Mark T. Gladwin & Prithu Sundd. (2020) Intravascular hemolysis triggers ADP-mediated generation of platelet-rich thrombi in precapillary pulmonary arterioles. JCI Insight 5:14.
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Şeyda KARA & Muharrem AKCAN. (2020) Disulfide-rich peptides in drug development. Hacettepe Journal of Biology and Chemistry 48:3, pages 219-229.
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Hue N. T. Tran, Poanna Tran, Jennifer R. Deuis, Akello J. Agwa, Alan H. Zhang, Irina Vetter & Christina I. Schroeder. (2019) Enzymatic Ligation of a Pore Blocker Toxin and a Gating Modifier Toxin: Creating Double-Knotted Peptides with Improved Sodium Channel Na V 1.7 Inhibition . Bioconjugate Chemistry 31:1, pages 64-73.
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Hamed Memariani, Mojtaba Memariani, Hamideh Moravvej & Mohammad Shahidi-Dadras. (2019) Melittin: a venom-derived peptide with promising anti-viral properties. European Journal of Clinical Microbiology & Infectious Diseases 39:1, pages 5-17.
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Mohamed Abd El-Aziz, Garcia Soares & Stockand. (2019) Snake Venoms in Drug Discovery: Valuable Therapeutic Tools for Life Saving. Toxins 11:10, pages 564.
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Gian Luigi Mariottini & Irwin Darren Grice. (2019) Natural Compounds and Drug Discovery: Can Cnidarian Venom Play a Role?. Central Nervous System Agents in Medicinal Chemistry 19:2, pages 114-118.
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Reka A. Otvos, Kristina B.M. Still, Govert W. Somsen, August B. Smit & Jeroen Kool. (2019) Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays. SLAS Discovery 24:3, pages 362-385.
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Ana Rita Thomazela Machado, Alexandre Ferro Aissa, Diego Luis Ribeiro, Rui Seabra Ferreira Jr., Suely Vilela Sampaio & Lusânia Maria Greggi Antunes. (2019) BjussuLAAO-II induces cytotoxicity and alters DNA methylation of cell-cycle genes in monocultured/co-cultured HepG2 cells. Journal of Venomous Animals and Toxins including Tropical Diseases 25.
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Isadora Sousa de Oliveira, Rafaella Varzoni Manzini, Isabela Gobbo Ferreira, Iara Aimê Cardoso, Karla de Castro Figueiredo Bordon, Ana Rita Thomazela Machado, Lusânia Maria Greggi Antunes, José Cesar Rosa & Eliane Candiani Arantes. (2018) Cell migration inhibition activity of a non-RGD disintegrin from Crotalus durissus collilineatus venom. Journal of Venomous Animals and Toxins including Tropical Diseases 24:1.
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Yumiko Sakurai, Elaissa T. Hardy, Byungwook Ahn, Reginald Tran, Meredith E. Fay, Jordan C. Ciciliano, Robert G. Mannino, David R. Myers, Yongzhi Qiu, Marcus A. Carden, W. Hunter Baldwin, Shannon L. Meeks, Gary E. Gilbert, Shawn M. Jobe & Wilbur A. Lam. (2018) A microengineered vascularized bleeding model that integrates the principal components of hemostasis. Nature Communications 9:1.
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Biswajit Gorai & Thirunavukkarasu Sivaraman. (2017) Delineating residues for haemolytic activities of snake venom cardiotoxin 1 from Naja naja as probed by molecular dynamics simulations and in vitro validations. International Journal of Biological Macromolecules 95, pages 1022-1036.
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V.O. Zambelli, K.F.M. Pasqualoto, G. Picolo, A.M. Chudzinski-Tavassi & Y. Cury. (2016) Harnessing the knowledge of animal toxins to generate drugs. Pharmacological Research 112, pages 30-36.
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Gian Luigi Mariottini. 2016. The Cnidaria, Past, Present and Future. The Cnidaria, Past, Present and Future 653 668 .
Andrea Caporali, Marco Meloni, Audrey Nailor, Tijana Mitić, Saran Shantikumar, Federica Riu, Graciela B. Sala-Newby, Lorraine Rose, Marie Besnier, Rajesh Katare, Christine Voellenkle, Paul Verkade, Fabio Martelli, Paolo Madeddu & Costanza Emanueli. (2015) p75NTR-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte–endothelial crosstalk in diabetes after limb ischaemia. Nature Communications 6:1.
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David P. Sargeant, Michael R. Gryk, Mark W. Maciejewski, Vishal Thapar, Vamsi Kundeti, Sanguthevar Rajasekaran, Pedro Romero, Keith Dunker, Shun-Cheng Li, Tomonori Kaneko & Martin R. Schiller. (2012) Secondary Structure, a Missing Component of Sequence-Based Minimotif Definitions. PLoS ONE 7:12, pages e49957.
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Akriti Rastogi, Sumit Biswas, Angshuman Sarkar & Dibakar Chakrabarty. (2012) Anticoagulant activity of Moon jellyfish (Aurelia aurita) tentacle extract. Toxicon 60:5, pages 719-723.
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Edo Kaluski, Bunyad Haider, Olga Milo-Cotter & Marc Klapholz. (2007) Glycoprotein IIb/IIIa inhibitors: questioning indications and treatment algorithms. Cardiovascular Revascularization Medicine 8:4, pages 281-288.
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Geoff W. Birrell, Stephen T.H. Earl, Tristan P. Wallis, Paul P. Masci, John de Jersey, Jeffrey J. Gorman & Martin F. Lavin. (2007) The Diversity of Bioactive Proteins in Australian Snake Venoms. Molecular & Cellular Proteomics 6:6, pages 973-986.
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Yajnavalka Banerjee, Jun Mizuguchi, Sadaaki Iwanaga & R. Manjunatha Kini. (2005) Hemextin AB Complex, a Unique Anticoagulant Protein Complex from Hemachatus haemachatus (African Ringhals Cobra) Venom That Inhibits Clot Initiation and Factor VIIa Activity. Journal of Biological Chemistry 280:52, pages 42601-42611.
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