Advanced search
Publication Cover
Expert Opinion on Pharmacotherapy Volume 7, 2006 - Issue 10
Submit an article Journal homepage
238
Views
19
CrossRef citations to date
0
Altmetric
Review

Managing psychiatric disorders with antidiabetic agents: translational research and treatment opportunities

Roger S McIntyre Associate Professor of Psychiatry and Pharmacology, Head, Mood Disorders Psychopharmacology Unit, University Health Network, 399 Bathurst Street – Toronto, ON, M5T 2S8, Canada. [email protected]; Department of Pharmacology, University of Toronto, Toronto, ON, Canada; Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, ON, Canada; University Health Network, Toronto, ON, Canada; Department of Medicine and Physiology, University of Toronto, Toronto, ON, Canada
,
Joanna K Soczynska Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, ON, Canada
,
Gary F Lewis University Health Network, Toronto, ON, Canada; Department of Medicine and Physiology, University of Toronto, Toronto, ON, Canada; Mount Sinai Hospital, Toronto, ON, Canada
,
Glenda M MacQueen Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada
,
Jakub Z Konarski Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada
&
Sidney H Kennedy Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, ON, Canada; University Health Network, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada; Assistant Professor of Psychiatry and Pharmacology, Head, Department of Psychiatry, University of Toronto, Toronto, ON, Canada
Pages 1305-1321 | Published online: 29 Jun 2006

Citations (19)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Eva Gunde, Ryan Blagdon & Tomas Hajek. (2011) White matter hyperintensities – from medical comorbidities to bipolar disorders and back. Annals of Medicine 43:8, pages 571-580.
Read now
Elisa Brietzke, Flávio Kapczinski, Rodrigo Grassi-Oliveira, Iria Grande, Eduard Vieta & Roger S McIntyre. (2011) Insulin dysfunction and allostatic load in bipolar disorder. Expert Review of Neurotherapeutics 11:7, pages 1017-1028.
Read now
Owen M. Wolkowitz, Victor I. Reus & Synthia H. Mellon. (2011) Of sound mind and body: depression, disease, and accelerated aging. Dialogues in Clinical Neuroscience 13:1, pages 25-39.
Read now
Roger S. Mclntyre, Ha T. Nguyen, Joanna K. Soczynska, Maria Teresa C. Lourenco, Hanna O. Woldeyohannes & Jakub Z. Konarski. (2008) Medical and substance-related comorbidity in bipolar disorder: translational research and treatment opportunities. Dialogues in Clinical Neuroscience 10:2, pages 203-213.
Read now
Joanna K Soczynska, Sidney H Kennedy, Cindy SM Chow, Hanna O Woldeyohannes, Jakub Z Konarski & Roger S McIntyre. (2008) Acetyl-L-carnitine and α-lipoic acid: possible neurotherapeutic agents for mood disorders?. Expert Opinion on Investigational Drugs 17:6, pages 827-843.
Read now
Roger S. McIntyre, Joanna K. Soczynska, Jakub Z. Konarski, Hanna O. Woldeyohannes, Candy W.Y. Law, Andrew Miranda, Don Fulgosi & Sidney H. Kennedy. (2007) Should Depressive Syndromes Be Reclassified as “Metabolic Syndrome Type II”?. Annals of Clinical Psychiatry 19:4, pages 257-264.
Read now

Articles from other publishers (13)

Nicholas L. DePace & Joseph ColomboNicholas L. DePace & Joseph Colombo. 2019. Clinical Autonomic and Mitochondrial Disorders. Clinical Autonomic and Mitochondrial Disorders 397 499 .
Sabrina C. da Costa, Rodrigo Machado-Vieira & Jair C. Soares. (2018) Novel Therapeutics in Bipolar Disorder. Current Treatment Options in Psychiatry 5:1, pages 162-181.
Crossref
Eder Gambeta, Camila Pasquini de Souza, Helen de Morais & Janaina Menezes Zanoveli. (2015) Reestablishment of the hyperglycemia to the normal levels seems not to be essential to the anxiolytic-like effect induced by insulin. Metabolic Brain Disease 31:3, pages 563-571.
Crossref
Juan C. Leza, Borja García-Bueno, Miquel Bioque, Celso Arango, Mara Parellada, Kim Do, Patricio O’Donnell & Miguel Bernardo. (2015) Inflammation in schizophrenia: A question of balance. Neuroscience & Biobehavioral Reviews 55, pages 612-626.
Crossref
Tomas Hajek, Cynthia Calkin, Ryan Blagdon, Claire Slaney & Martin Alda. (2015) Type 2 Diabetes Mellitus: A Potentially Modifiable Risk Factor for Neurochemical Brain Changes in Bipolar Disorders. Biological Psychiatry 77:3, pages 295-303.
Crossref
Zoltán Sarnyai, Cassandra Jashar & Berend Olivier. (2015) Modeling combined schizophrenia-related behavioral and metabolic phenotypes in rodents. Behavioural Brain Research 276, pages 130-142.
Crossref
Borja García-Bueno, Miquel Bioque, Karina S. Mac-Dowell, M. Fe Barcones, Monica Martínez-Cengotitabengoa, Laura Pina-Camacho, Roberto Rodríguez-Jiménez, Pilar A. Sáiz, Carmen Castro, Amalia Lafuente, Javier Santabárbara, Ana González-Pinto, Mara Parellada, Gabriel Rubio, M. Paz García-Portilla, Juan A. Micó, Miguel Bernardo & Juan C. Leza. (2014) Pro-/Anti-inflammatory Dysregulation in Patients With First Episode of Psychosis: Toward an Integrative Inflammatory Hypothesis of Schizophrenia. Schizophrenia Bulletin 40:2, pages 376-387.
Crossref
Leila Moezi, Zeinab Janahmadi, Zahra Amirghofran, Ali Akbar Nekooeian & Ahmad R. Dehpour. (2014) The increased gastroprotective effect of pioglitazone in cholestatic rats: role of nitric oxide and tumour necrosis factor alpha. International Journal of Experimental Pathology 95:1, pages 78-85.
Crossref
Hamidreza Roohafza, Pedram Shokouh, Masoumeh Sadeghi, Zahra Alikhassy & Nizal Sarrafzadegan. (2014) A Possible Role for Pioglitazone in the Management of Depressive Symptoms in Metabolic Syndrome Patients (EPICAMP Study): A Double Blind, Randomized Clinical Trial. International Scholarly Research Notices 2014, pages 1-9.
Crossref
Leila Moezi, Reza Heidari, Zahra Amirghofran, Ali Akbar Nekooeian, Ahmad Monabati & Ahmad R. Dehpour. (2013) Enhanced anti-ulcer effect of pioglitazone on gastric ulcers in cirrhotic rats: The role of nitric oxide and IL-1β. Pharmacological Reports 65:1, pages 134-143.
Crossref
James K. Rustad, Dominique L. Musselman & Charles B. Nemeroff. (2011) The relationship of depression and diabetes: Pathophysiological and treatment implications. Psychoneuroendocrinology 36:9, pages 1276-1286.
Crossref
Mohammad Salehi Sadaghiani, Mehrak Javadi-Paydar, Mohammad Hadi Gharedaghi, Yashar Yousefzadeh Fard & Ahmad Reza Dehpour. (2011) Antidepressant-like effect of pioglitazone in the forced swimming test in mice: The role of PPAR-gamma receptor and nitric oxide pathway. Behavioural Brain Research 224:2, pages 336-343.
Crossref
Hui Hua Chang, Yen Kuang Yang, Po Wu Gean, Hui Chun Huang, Po See Chen & Ru Band Lu. (2010) The role of valproate in metabolic disturbances in bipolar disorder patients. Journal of Affective Disorders 124:3, pages 319-323.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.