153
Views
21
CrossRef citations to date
0
Altmetric
Drug Evaluation

Lumiracoxib in the management of osteoarthritis and acute pain

&
Pages 1551-1564 | Published online: 30 Jul 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Anthony P. Dickie, Claire E. Wilson, Kay Schreiter, Roland Wehr, Ian D. Wilson & Rob Riley. (2017) Lumiracoxib metabolism in male C57bl/6J mice: characterisation of novel in vivo metabolites. Xenobiotica 47:6, pages 538-546.
Read now
Avinash K Bhandary, Gary P Chimes & Gerard A Malanga. (2010) Investigational pharmacology for low back pain. Journal of Pain Research 3, pages 169-181.
Read now
Teodorico C Ramalho, Marcus VJ Rocha, Elaine FF da Cunha & Matheus P Freitas. (2009) The search for new COX-2 inhibitors: a review of 2002 – 2008 patents. Expert Opinion on Therapeutic Patents 19:9, pages 1193-1228.
Read now

Articles from other publishers (18)

Qi Sun, Yuanzhen Zhang, Yilan Ding, Wenqing Xie, Hengzhen Li, Shaohua Li, Yusheng Li & Ming Cai. (2022) Inhibition of PGE2 in Subchondral Bone Attenuates Osteoarthritis. Cells 11:17, pages 2760.
Crossref
Jun Sun, Lei Zhang, Lingchun Zhang & Qingwang Liu. (2021) A validated UHPLC–MS/MS method for simultaneous determination of lumiracoxib and its hydroxylation and acyl glucuronidation metabolites in rat plasma: Application to a pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis 201, pages 114105.
Crossref
Weijie Jiao, Xu Zhao, Guiyue Wu, Xiangyun Zhang, Hong Wu & Yinglin Cui. (2020) Bioactivation of lumiracoxib in human liver microsomes: Formation of GSH‐ and amino adducts through acyl glucuronide. Drug Testing and Analysis 12:6, pages 827-835.
Crossref
Gerd Rosenkranz. 2019. Exploratory Subgroup Analyses in Clinical Research. Exploratory Subgroup Analyses in Clinical Research 197 215 .
A.P. Dickie, C.E. Wilson, K. Schreiter, R. Wehr, E.M. Wilson, J. Bial, N. Scheer, I.D. Wilson & R.J. Riley. (2017) The pharmacokinetics and metabolism of lumiracoxib in chimeric humanized and murinized FRG mice. Biochemical Pharmacology 135, pages 139-150.
Crossref
Zelalem PetrosEyasu MakonnenEleni Aklillu. (2017) Genome-Wide Association Studies for Idiosyncratic Drug-Induced Hepatotoxicity: Looking Back–Looking Forward to Next-Generation Innovation. OMICS: A Journal of Integrative Biology 21:3, pages 123-131.
Crossref
Yi Yun Pang, Yee Min Tan, Eric Chun Yong Chan & Han Kiat Ho. (2016) Phase I Metabolic Stability and Electrophilic Reactivity of 2-Phenylaminophenylacetic Acid Derived Compounds. Chemical Research in Toxicology 29:7, pages 1118-1131.
Crossref
François Ballet. (2015) Preventing Drug-Induced Liver Injury: How Useful Are Animal Models?. Digestive Diseases 33:4, pages 477-485.
Crossref
Yi Yun Pang, Wee Kiang Yeo, Kep Yong Loh, Mei Lin Go & Han Kiat Ho. (2014) Structure–toxicity relationship and structure–activity relationship study of 2-phenylaminophenylacetic acid derived compounds. Food and Chemical Toxicology 71, pages 207-216.
Crossref
Mario I. Ortiz, Gilberto Castañeda-Hernández, Jeannett A. Izquierdo-Vega, Manuel Sánchez-Gutiérrez, Héctor A. Ponce-Monter & Vinicio Granados-Soto. (2012) Role of ATP-sensitive K+ channels in the antinociception induced by non-steroidal anti-inflammatory drugs in streptozotocin-diabetic and non-diabetic rats. Pharmacology Biochemistry and Behavior 102:1, pages 163-169.
Crossref
Maximiliano S. Sangoi, Micheli Wrasse-Sangoi, Paulo R. Oliveira & Larissa S. Bernardi. (2011) Determination of lumiracoxib by a validated stability-indicating MEKC method and identification of its degradation products by LC-ESI-MS studies. Journal of Separation Science 34:15, pages 1867-1874.
Crossref
Ana Alfirevic & Munir Pirmohamed. (2010) Drug Induced Hypersensitivity and the HLA Complex. Pharmaceuticals 4:1, pages 69-90.
Crossref
Jonathan B Singer, Steve Lewitzky, Elisabeth Leroy, Fan Yang, Xiaojun Zhao, Lloyd Klickstein, Timothy M Wright, Joanne Meyer & Charles A Paulding. (2010) A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nature Genetics 42:8, pages 711-714.
Crossref
F. Ballet. (2010) Back to basics for idiosyncratic drug-induced liver injury: Dose and metabolism make the poison. Gastroentérologie Clinique et Biologique 34:6-7, pages 348-350.
Crossref
K. D. Rainsford. (2009) Ibuprofen: pharmacology, efficacy and safety. Inflammopharmacology 17:6, pages 275-342.
Crossref
Ping Kang, Deepak Dalvie, Evan Smith & Matt Renner. (2008) Bioactivation of Lumiracoxib by Peroxidases and Human Liver Microsomes: Identification of Multiple Quinone Imine Intermediates and GSH Adducts. Chemical Research in Toxicology 22:1, pages 106-117.
Crossref
Benjamin A. White & Stephen H. Thomas. 2009. Emergency Department Analgesia. Emergency Department Analgesia 61 69 .
Ying Li, J. Greg Slatter, Zhoupeng Zhang, Yan Li, George A. Doss, Matthew P. Braun, Ralph A. Stearns, Dennis C. Dean, Thomas A. Baillie & Wei Tang. (2008) In Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver Preparations. Drug Metabolism and Disposition 36:2, pages 469-473.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.