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Review

The use of plasma-derived C1 inhibitor in the treatment of hereditary angioedema

, MD, , , &
Pages 3173-3181 | Published online: 26 Nov 2007

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Read on this site (5)

Roberto Castelli, Andrea Zanichelli & Massimo Cugno. (2013) Therapeutic options for patients with angioedema due to C1-inhibitor deficiencies: from pathophysiology to the clinic. Immunopharmacology and Immunotoxicology 35:1, pages 181-190.
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Hilary J Longhurst. (2010) Management of acute attacks of hereditary angioedema: potential role of icatibant. Vascular Health and Risk Management 6, pages 795-802.
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Lourdes Pastó Cardona, Ramon Lleonart Bellfill & Joaquim Marcoval Caus. (2010) Recent developments in the treatment of acute abdominal and facial attacks of hereditary angioedema: focus on human C1 esterase inhibitor. The Application of Clinical Genetics 3, pages 133-146.
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Lilian Varga & Henriette Farkas. (2008) Treatment of type I and II hereditary angioedema with Rhucin®, a recombinant human C1 inhibitor. Expert Review of Clinical Immunology 4:6, pages 653-661.
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Diana Wouters, Ineke Wagenaar-Bos, Marieke van Ham & Sacha Zeerleder. (2008) C1 inhibitor: just a serine protease inhibitor? New and old considerations on therapeutic applications of C1 inhibitor. Expert Opinion on Biological Therapy 8:8, pages 1225-1240.
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Articles from other publishers (30)

Marcel Levi & Danny M Cohn. (2019) The Role of Complement in Hereditary Angioedema. Transfusion Medicine Reviews 33:4, pages 243-247.
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Marcel Levi, Danny M. Cohn & Sacha Zeerleder. (2019) Hereditary angioedema: Linking complement regulation to the coagulation system. Research and Practice in Thrombosis and Haemostasis 3:1, pages 38-43.
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Ashwag Aloyouny & Eric T. Stoopler. (2016) Vibrational angioedema: considerations for oral health care providers. Special Care in Dentistry 36:6, pages 335-338.
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Daniel Schürmann, Eva Herzog, Elmar Raquet, Marc Nolte, Frauke May, Jochen Müller-Cohrs, Jenny Björkqvist, Gerhard Dickneite & Ingo Pragst. (2017) C1-esterase inhibitor treatment: preclinical safety aspects on the potential prothrombotic risk. Thrombosis and Haemostasis 112:11, pages 960-971.
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Jan Over, Christine Kramer, Anky Koenderman, Diana Wouters & Sacha Zeerleder. 2013. Production of Plasma Proteins for Therapeutic Use. Production of Plasma Proteins for Therapeutic Use 241 258 .
Paloma Campo, Tahía D. Fernandez, Gabriela Canto & Cristobalina Mayorga. (2013) Angioedema induced by angiotensin-converting enzyme inhibitors. Current Opinion in Allergy & Clinical Immunology 13:4, pages 337-344.
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Getaw Worku Hassen, Hossein Kalantari, Monica Parraga, Roger Chirurgi, Carlos Meletiche, Christopher Chan, Jacque Ciarlo, Farhad Gazi, Christopher Lobaito, Siamak Tadayon, Selamawit Yemane & Carolina Velez. (2013) Fresh Frozen Plasma for Progressive and Refractory Angiotensin-Converting Enzyme Inhibitor-induced Angioedema. The Journal of Emergency Medicine 44:4, pages 764-772.
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M. Maurer & L.C. Parish. (2013) The dermatology view of hereditary angio-oedema: practical diagnostic and management considerations. Journal of the European Academy of Dermatology and Venereology 27:2, pages 133-141.
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Anurag Relan, Kamran Bakhtiari, Edwin S. van Amersfoort, Joost C.M. Meijers & C. Erik Hack. (2012) Recombinant C1-Inhibitor. BioDrugs 26:1, pages 43-52.
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M. Cicardi, K. Bork, T. Caballero, T. Craig, H. H. Li, H. Longhurst, A. Reshef & B. Zuraw. (2012) Evidence-based recommendations for the therapeutic management of angioedema owing to hereditary C1 inhibitor deficiency: consensus report of an International Working Group. Allergy 67:2, pages 147-157.
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Marc A. Riedl, David S. Hurewitz, Robyn Levy, Paula J. Busse, David Fitts & Ira Kalfus. (2012) Nanofiltered C1 esterase inhibitor (human) for the treatment of acute attacks of hereditary angioedema: an open-label trial. Annals of Allergy, Asthma & Immunology 108:1, pages 49-53.
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T. J. Craig, A. K. Bewtra, S. L. Bahna, D. Hurewitz, L. C. Schneider, R. J. Levy, J. N. Moy, J. Offenberger, K. W. Jacobson, W. H. Yang, F. Eidelman, G. Janss, F. R. Packer, M. A. Rojavin, T. Machnig, H.-O. Keinecke & R. L. Wasserman. (2011) C1 esterase inhibitor concentrate in 1085 Hereditary Angioedema attacks - final results of the I.M.P.A.C.T.2 study. Allergy 66:12, pages 1604-1611.
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Marco Cicardi & Massimo Cugno. 2011. Kinins. Kinins 289 306 .
A. Zanichelli, R. Vacchini, M. Badini, V. Penna & M. Cicardi. (2011) Standard care impact on angioedema because of hereditary C1 inhibitor deficiency: a 21-month prospective study in a cohort of 103 patients. Allergy 66:2, pages 192-196.
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Richard G. Gower, Paula J. Busse, Emel Aygören-Pürsün, Amin J. Barakat, Teresa Caballero, Mark Davis-Lorton, Henriette Farkas, David S. Hurewitz, Joshua S. Jacobs, Douglas T. Johnston, William Lumry & Marcus Maurer. (2011) Hereditary Angioedema Caused By C1-Esterase Inhibitor Deficiency: A Literature-Based Analysis and Clinical Commentary on Prophylaxis Treatment Strategies. World Allergy Organization Journal 4:2, pages S9-S21.
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Solange Oliveira Rodrigues ValleAlfeu Tavares FrançaRegis A. CamposAnete Sevciovic Grumach. (2011) C1 Esterase Inhibitor (Human) for the Treatment of Acute Hereditary Angioedema. Clinical medicine. Blood disorders 4, pages CMBD.S4090.
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Richard G Gower, Paula J Busse, Emel Aygören-Pürsün, Amin J Barakat, Teresa Caballero, Mark Davis-Lorton, Henriette Farkas, David S Hurewitz, Joshua S Jacobs, Douglas T Johnston, William Lumry & Marcus Maurer. (2011) Hereditary Angioedema Caused By C1-Esterase Inhibitor Deficiency: A Literature-Based Analysis and Clinical Commentary on Prophylaxis Treatment Strategies. World Allergy Organization Journal 4, pages S9-S21.
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Ibolya Czaller, Katalin Molnár, Dorottya Csuka, Lilian Varga & Henriette Farkas. (2011) Successful Outcome Using C1-Inhibitor Concentrate In Acute Pancreatitis Caused By Hereditary Angioedema. Gastroenterology Nursing 34:1, pages 60-63.
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Lilian Varga, George Füst, Dorottya Csuka & Henriette Farkas. (2011) Treatment with C1-inhibitor concentrate does not induce IgM type anti-C1 inhibitor antibodies in patients with hereditary angioedema. Molecular Immunology 48:4, pages 572-576.
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Richard L. Wasserman, Robyn J. Levy, Againdra K. Bewtra, David Hurewitz, Timothy J. Craig, Peter C. Kiessling, Heinz-Otto Keinecke & Jonathan A. Bernstein. (2011) Prospective study of C1 esterase inhibitor in the treatment of successive acute abdominal and facial hereditary angioedema attacks. Annals of Allergy, Asthma & Immunology 106:1, pages 62-68.
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Marco Cicardi & Andrea Zanichelli. (2010) Angioedema due to C1 inhibitor deficiency in 2010. Internal and Emergency Medicine 5:6, pages 481-486.
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Timothy J. Craig, Richard L. Wasserman, Robyn J. Levy, Againdra K. Bewtra, Lynda Schneider, Flint Packer, William H. Yang, Heinz-Otto Keinecke & Peter C. Kiessling. (2010) Prospective Study of Rapid Relief Provided by C1 Esterase Inhibitor in Emergency Treatment of Acute Laryngeal Attacks in Hereditary Angioedema. Journal of Clinical Immunology 30:6, pages 823-829.
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Bruce Zuraw, Marco Cicardi, Robyn J. Levy, Jan H. Nuijens, Anurag Relan, Sonja Visscher, Gerald Haase, Leonard Kaufman & C. Erik Hack. (2010) Recombinant human C1-inhibitor for the treatment of acute angioedema attacks in patients with hereditary angioedema. Journal of Allergy and Clinical Immunology 126:4, pages 821-827.e14.
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Inmaculada Martinez-Saguer, Eva Rusicke, Emel Aygören-Pürsün, Christine Heller, Thomas Klingebiel & Wolfhart Kreuz. (2010) Characterization of acute hereditary angioedema attacks during pregnancy and breast-feeding and their treatment with C1 inhibitor concentrate. American Journal of Obstetrics and Gynecology 203:2, pages 131.e1-131.e7.
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Inmaculada Martinez-Saguer, Eva Rusicke, Emel Aygören-Pürsün, Nils von Hentig, Thomas Klingebiel & Wolfhart Kreuz. (2010) Pharmacokinetic analysis of human plasma-derived pasteurized C1-inhibitor concentrate in adults and children with hereditary angioedema: a prospective study. Transfusion 50:2, pages 354-360.
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Cecilia L. BASIGLIO, Sandra M. ARRIAGA, Fabián PELUSA, Adriana M. ALMARÁ, Jaime KAPITULNIK & Aldo D. MOTTINO. (2010) Complement activation and disease: protective effects of hyperbilirubinaemia. Clinical Science 118:2, pages 99-113.
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Timothy J. Craig, Robyn J. Levy, Richard L. Wasserman, Againdra K. Bewtra, David Hurewitz, Krystyna Obtułowicz, Avner Reshef, Bruce Ritchie, Dumitru Moldovan, Todor Shirov, Vesna Grivcheva-Panovska, Peter C. Kiessling, Heinz-Otto Keinecke & Jonathan A. Bernstein. (2009) Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks. Journal of Allergy and Clinical Immunology 124:4, pages 801-808.
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Wolfhart Kreuz, Inmaculada Martinez-Saguer, Emel Aygören-Pürsün, Eva Rusicke, Christine Heller & Thomas Klingebiel. (2009) C1-inhibitor concentrate for individual replacement therapy in patients with severe hereditary angioedema refractory to danazol prophylaxis. Transfusion 49:9, pages 1987-1995.
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Massimo Cugno, Andrea Zanichelli, Fabrizio Foieni, Sonia Caccia & Marco Cicardi. (2009) C1-inhibitor deficiency and angioedema: molecular mechanisms and clinical progress. Trends in Molecular Medicine 15:2, pages 69-78.
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László Beinrohr, József Dobó, Péter Závodszky & Péter Gál. (2008) C1, MBL–MASPs and C1-inhibitor: novel approaches for targeting complement-mediated inflammation. Trends in Molecular Medicine 14:12, pages 511-521.
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