244
Views
43
CrossRef citations to date
0
Altmetric
Drug Evaluation

The evolving role of lenalidomide in the treatment of hematologic malignancies

&
Pages 497-509 | Published online: 19 Feb 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Nilanjan Ghosh, Michael R Grunwald, Omotayo Fasan & Manisha Bhutani. (2015) Expanding role of lenalidomide in hematologic malignancies. Cancer Management and Research 7, pages 105-119.
Read now
Roberto Castelli, Nicola Orofino, Agnese Losurdo, Roberta Gualtierotti & Massimo Cugno. (2014) Choosing treatment options for patients with relapsed/refractory multiple myeloma. Expert Review of Anticancer Therapy 14:2, pages 199-215.
Read now
Roberto Castelli, Antonino Cannavò, Fabio Conforti, Giovanni Grava & Agostino Cortelezzi. (2012) Immunomodulatory drugs in multiple myeloma: from molecular mechanisms of action to clinical practice. Immunopharmacology and Immunotoxicology 34:5, pages 740-753.
Read now
Ali Tabarroki & Ramon V Tiu. (2012) Immunomodulatory agents in myelofibrosis. Expert Opinion on Investigational Drugs 21:8, pages 1141-1154.
Read now
Patrizia Falco, Federica Cavallo, Alessandra Larocca, Anna Marina Liberati, Pellegrino Musto, Mario Boccadoro & Antonio Palumbo. (2008) Lenalidomide and its role in the management of multiple myeloma. Expert Review of Anticancer Therapy 8:6, pages 865-874.
Read now

Articles from other publishers (38)

Punna VenkateshwarluMehul M. Patel. (2021) A Review: Method Development Validation and Degradation Studies of some Anticancer Drugs. Research Journal of Pharmacy and Technology, pages 5443-5448.
Crossref
Punna VenkateshwarluMehul M. Patel. (2021) Method Development and Validation of Degradation Studies of Lenalidomide by RP-HPLC. Research Journal of Pharmacy and Technology, pages 4281-4286.
Crossref
Yujin Li, Shirong Zhu, Weiyi Liu, Jing Ming, Xueying Wang & Xiaomei Hu. (2020) Ruxolitinib-based combinations in the treatment of myelofibrosis: worth looking forward to. Annals of Hematology 99:6, pages 1161-1176.
Crossref
Flaminia Coluzzi, Roman Rolke & Sebastiano Mercadante. (2019) Pain Management in Patients with Multiple Myeloma: An Update. Cancers 11:12, pages 2037.
Crossref
Premanand Ranganathan, V. Gunasekaran, Indrajeet Singhvi & Mohammad Javed Ansari. (2019) Development and validation of Lenalidomide in human plasma by LC-MS/MS. Saudi Journal of Biological Sciences 26:7, pages 1843-1847.
Crossref
Yilun Yan, Jun Fan, Dong Guo, Yuemei Lin, Yecai Lai, Tai Wang, Hao Gao, Xinsheng Yao & Weiguang Zhang. (2018) Lenalidomide, a blockbuster drug for the treatment of multiple myeloma: Semipreparative separation through supercritical fluid chromatography and vibrational circular dichroism spectroscopy. Journal of Separation Science 41:20, pages 3840-3847.
Crossref
Veera Venkata Satyanarayana Reddy Karri, Nagasamy Venkatesh Dhandapani, Sai Sandeep Mannemala, Kollipara Radhakrishna, Shashank Mulukutla & Dedeepya Sudunagunta. (2017) Ameliorating the antitumor activity of lenalidomide using PLGA nanoparticles for the treatment of multiple myeloma. Brazilian Journal of Pharmaceutical Sciences 53:2.
Crossref
Beatriz Guglieri-López, Alejandro Pérez-Pitarch, Maria Amparo Martinez-Gómez, Begoña Porta-Oltra, Mónica Climente-Martí & Matilde Merino-Sanjuán. (2016) A Wide Linearity Range Method for the Determination of Lenalidomide in Plasma by High-Performance Liquid Chromatography: Application to Pharmacokinetic Studies. SLAS Technology 21:6, pages 806-810.
Crossref
Nourah Z. Alzoman. (2016) A Validated Stability-Indicating and Stereoselective HPLC Method for the Determination of Lenalidomide Enantiomers in Bulk Form and Capsules. Journal of Chromatographic Science 54:5, pages 730-735.
Crossref
Krishna Pocha & G. Devala Rao. (2014) Rapid determination of lenalidomide in rat plasma by an ultra performance liquid chromatography/tandem mass spectrometric method. Medicinal Chemistry Research 24:2, pages 459-467.
Crossref
Hadir M. Maher, Nourah Z. Alzoman, Mona M. Alshehri, Haya I. Aljohar, Shereen Shehata, Manal Alossaimi & Norah O. Abanmy. (2015) Simultaneous determination of dexamethasone and lenalidomide in rat plasma by solid phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry: application to pharmacokinetic studies. RSC Advances 5:119, pages 98600-98609.
Crossref
Riccardo Colombo, Paolo Gallipoli & Roberto Castelli. (2014) Thrombosis and Hemostatic Abnormalities in Hematological Malignancies. Clinical Lymphoma Myeloma and Leukemia 14:6, pages 441-450.
Crossref
Thandapani Gomathi, C. Govindarajan, Maximas H. Rose H.R.P.N. Sudha, P.K. Mohamed Imran, Jayachandran Venkatesan & Se-Kwon Kim. (2014) Studies on drug-polymer interaction, in vitro release and cytotoxicity from chitosan particles excipient. International Journal of Pharmaceutics 468:1-2, pages 214-222.
Crossref
Susanne Koeppen. (2014) Treatment of Multiple Myeloma: Thalidomide-, Bortezomib-, and Lenalidomide-Induced Peripheral Neuropathy. Oncology Research and Treatment 37:9, pages 506-513.
Crossref
Muzaffar Iqbal, Tanveer A Wani, Nasr Y Khalil & Ibrahim A Darwish. (2013) Development and validation of ultra-performance liquid chromatographic method with tandem mass spectrometry for determination of lenalidomide in rabbit and human plasma. Chemistry Central Journal 7:1.
Crossref
Roberto CastelliRoberta GualtierottiNicola OrofinoAgnese LosurdoSara GandolfiMassimo Cugno. (2013) Current and Emerging Treatment Options for Patients with Relapsed Myeloma. Clinical Medicine Insights: Oncology 7, pages CMO.S8014.
Crossref
T. Guglielmelli, S. Bringhen, S. Rrodhe, F. Gay, F. Cavallo, A. Berruti, V. Montefusco, E. Piro, G. Benevolo, M.T. Petrucci, T. Caravita, M. Offidani, P. Corradini, M. Boccadoro, G. Saglio & A. Palumbo. (2011) Previous thalidomide therapy may not affect lenalidomide response and outcome in relapse or refractory multiple myeloma patients. European Journal of Cancer 47:6, pages 814-818.
Crossref
Deng Wei, Ya Mingxi, Xu Jianwang, Zhang Hao, Li Ming & Li Pei. (2011) Dexamethasone plus lenalidomide in treatment of multiple myeloma. Journal of Medical Colleges of PLA 26:1, pages 29-33.
Crossref
Morie A. Gertz & Raymond Comenzo. 2011. Bortezomib in the Treatment of Multiple Myeloma. Bortezomib in the Treatment of Multiple Myeloma 135 148 .
Heinz LudwigZdenek AdamRoman HajekRichard GreilElena TóthováFelix KeilEva Maria AutzingerJosef ThalerHeinz GisslingerAlois LangMiklós EgyedIrene WomastekNiklas Zojer. (2010) Light Chain–Induced Acute Renal Failure Can Be Reversed by Bortezomib-Doxorubicin-Dexamethasone in Multiple Myeloma: Results of a Phase II Study. Journal of Clinical Oncology 28:30, pages 4635-4641.
Crossref
Nianhang Chen, Henry Lau, Somesh Choudhury, Xiaomin Wang, Mahmoud Assaf & Oscar L. Laskin. (2013) Distribution of Lenalidomide Into Semen of Healthy Men After Multiple Oral Doses. The Journal of Clinical Pharmacology 50:7, pages 767-774.
Crossref
Ashley Sumrall, Ruth Fredericks, Anne Berthold & Grace Shumaker. (2009) Lenalidomide stops progression of multifocal epithelioid hemangioendothelioma including intracranial disease. Journal of Neuro-Oncology 97:2, pages 275-277.
Crossref
John Glaspy, Michael B. Atkins, Jon M. Richards, Sanjiv S. Agarwala, Steven O'Day, Robert D. Knight, J. Ulf Jungnelius & Agop Y. Bedikian. (2009) Results of a multicenter, randomized, double-blind, dose-evaluating phase 2/3 study of lenalidomide in the treatment of metastatic malignant melanoma. Cancer 115:22, pages 5228-5236.
Crossref
M A Dimopoulos, C Chen, A Spencer, R Niesvizky, M Attal, E A Stadtmauer, M T Petrucci, Z Yu, M Olesnyckyj, J B Zeldis, R D Knight & D M Weber. (2009) Long-term follow-up on overall survival from the MM-009 and MM-010 phase III trials of lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma. Leukemia 23:11, pages 2147-2152.
Crossref
Jian Li, Dao-Bin Zhou, Li Jiao, Ming Hui Duan, Wei Zhang, Yong Qiang Zhao & Ti Shen. (2009) Bortezomib and Dexamethasone Therapy for Newly Diagnosed Patients With Multiple Myeloma Complicated by Renal Impairment. Clinical Lymphoma and Myeloma 9:5, pages 394-398.
Crossref
Antonio Palumbo, Patrizia Falco, Antonietta Falcone, Giulia Benevolo, Letizia Canepa, Francesca Gay, Alessandra Larocca, Valeria Magarotto, Alessandro Gozzetti, Annalisa Luraschi, Fortunato Morabito, Andrea Nozza, Robert D. Knight, Jerome B. Zeldis, Mario Boccadoro & Maria Teresa Petrucci. (2009) Melphalan, Prednisone, and Lenalidomide for Newly Diagnosed Myeloma: Kinetics of Neutropenia and Thrombocytopenia and Time-to-Event Results. Clinical Lymphoma and Myeloma 9:2, pages 145-150.
Crossref
Antonio Palumbo, Meletios Dimopoulos, Jesus San Miguel, Jean-Luc Harousseau, Michel Attal, Mohamad Hussein, Stefan Knop, Heinz Ludwig, Marie von Lilienfeld-Toal & Pieter Sonneveld. (2009) Lenalidomide in combination with dexamethasone for the treatment of relapsed or refractory multiple myeloma. Blood Reviews 23:2, pages 87-93.
Crossref
Dan Zhu, Laura G. Corral, Yuedi W. Fleming & Bernd Stein. (2008) Immunomodulatory drugs Revlimid® (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation. Cancer Immunology, Immunotherapy 57:12, pages 1849-1859.
Crossref
A Alonci, A Allegra, G Bellomo, G Penna, A D'Angelo, E Quartarone & C Musolino. (2008) Evaluation of circulating endothelial cells, VEGF and VEGFR2 serum levels in patients with chronic myeloproliferative diseases. Hematological Oncology 26:4, pages 235-239.
Crossref
Yen-Ta Huang, Chih W. Hsu & Ted H. Chiu. (2008) Thalidomide and Its Analogs as Anticancer Agents. Tzu Chi Medical Journal 20:3, pages 188-195.
Crossref
M A Dimopoulos, E Kastritis, L Rosinol, J Bladé & H Ludwig. (2008) Pathogenesis and treatment of renal failure in multiple myeloma. Leukemia 22:8, pages 1485-1493.
Crossref
Antonio Palumbo, Jesús San Miguel, Pieter Sonneveld, Philippe Moreau, Johannes Drach, Gareth Morgan & Hermann Einsele. (2008) Lenalidomide: A new therapy for multiple myeloma. Cancer Treatment Reviews 34:3, pages 283-291.
Crossref
María‐Victoria Mateos, Ramón García‐Sanz, Enrique Colado, Juan Olazábal & Jesús San‐Miguel. (2007) Should prophylactic granulocyte‐colony stimulating factor be used in multiple myeloma patients developing neutropenia under lenalidomide‐based therapy?. British Journal of Haematology 140:3, pages 324-326.
Crossref
Sheeba K. Thomas, Tiffany A. Richards & Donna M. Weber. 2009. Myeloma Therapy. Myeloma Therapy 265 277 .
Sheeba K. Thomas, Tiffany A. Richards & Donna M. Weber. (2007) Lenalidomide in multiple myeloma. Best Practice & Research Clinical Haematology 20:4, pages 717-735.
Crossref
. (2007) Current Awareness in Hematological Oncology. Hematological Oncology 25:4, pages 204-211.
Crossref
Peter H. Wiernik. (2007) Leukemias and plasma cell dyscrasias. Update on Cancer Therapeutics 2:2, pages 73-99.
Crossref
Shridhar Hegde & Michelle Schmidt. 2007. Annual Reports in Medicinal Chemistry Volume 42. Annual Reports in Medicinal Chemistry Volume 42 505 554 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.