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Drug Evaluation

Darifenacin: a muscarinic M3-selective receptor antagonist for the treatment of overactive bladder

Pages 511-523 | Published online: 19 Feb 2007

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Sophie Ramsay, Élisabeth Lapointe & Stéphane Bolduc. (2022) Comprehensive overview of the available pharmacotherapy for the treatment of non-neurogenic overactive bladder in children. Expert Opinion on Pharmacotherapy 23:8, pages 991-1002.
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Hadi Mostafaei, Shahrokh F. Shariat, Hanieh Salehi-Pourmehr, Florian Janisch, Keiichiro Mori, Fahad Quhal & Sakineh Hajebrahimi. (2020) The clinical pharmacology of the medical treatment for overactive bladder in adults. Expert Review of Clinical Pharmacology 13:7, pages 707-720.
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Gillian F Wolff, George A Kuchel & Phillip P Smith. (2014) Overactive bladder in the vulnerable elderly. Research and Reports in Urology 6, pages 131-138.
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Umberto Leone Roberti Maggiore, Stefano Salvatore, Franco Alessandri, Valentino Remorgida, Massimo Origoni, Massimo Candiani, Pier Luigi Venturini & Simone Ferrero. (2012) Pharmacokinetics and toxicity of antimuscarinic drugs for overactive bladder treatment in females. Expert Opinion on Drug Metabolism & Toxicology 8:11, pages 1387-1408.
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Philip Gerretsen & Bruce G Pollock. (2011) Drugs with anticholinergic properties: a current perspective on use and safety. Expert Opinion on Drug Safety 10:5, pages 751-765.
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Articles from other publishers (19)

Yuichi Hattori, Kuniaki Ishii, Kazuhiko Yanai & Masao Endoh. (2022) The large part German medicine has played in the development of experimental pharmacology in Japan. Naunyn-Schmiedeberg's Archives of Pharmacology 396:1, pages 35-42.
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Sophia J. Wiedemann, Kelly Trimigliozzi, Erez Dror, Daniel T. Meier, Jose Alberto Molina-Tijeras, Leila Rachid, Christelle Le Foll, Christophe Magnan, Friederike Schulze, Marc Stawiski, Stéphanie P. Häuselmann, Hélène Méreau, Marianne Böni-Schnetzler & Marc Y. Donath. (2022) The cephalic phase of insulin release is modulated by IL-1β. Cell Metabolism 34:7, pages 991-1003.e6.
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José Carlos Truzzi, Fernando Gonçalves de Almeida, Carlos Alberto Sacomani, Joceara Reis & Flávio Eduardo Trigo Rocha. (2022) Neurogenic bladder – concepts and treatment recommendations. International braz j urol 48:2, pages 220-243.
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Evgenyi I. Kreydin, Cristiano M. Gomes & Francisco Cruz. (2021) Current pharmacotherapy of overactive bladder. International braz j urol 47:6, pages 1091-1107.
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Blayne Welk, Kathryn Richardson & Jalesh N. Panicker. (2021) The cognitive effect of anticholinergics for patients with overactive bladder. Nature Reviews Urology 18:11, pages 686-700.
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Ricardo Palmerola & Victor Nitti. 2019. Contemporary Pharmacotherapy of Overactive Bladder. Contemporary Pharmacotherapy of Overactive Bladder 291 314 .
Shizuo Yamada, Yoshihiko Ito, Saori Nishijima, Katsumi Kadekawa & Kimio Sugaya. (2018) Basic and clinical aspects of antimuscarinic agents used to treat overactive bladder. Pharmacology & Therapeutics 189, pages 130-148.
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Sarah Moreno, Stefanie Gerbig, Sabine Schulz, Bernhard Spengler, Martin Diener & Sandra Bader. (2016) Epithelial propionyl- and butyrylcholine as novel regulators of colonic ion transport. British Journal of Pharmacology 173:18, pages 2766-2779.
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Ruben Vardanyan & Victor Hruby. 2016. Synthesis of Best-Seller Drugs. Synthesis of Best-Seller Drugs 227 241 .
Sandra Bader & Martin Diener. (2015) Novel aspects of cholinergic regulation of colonic ion transport. Pharmacology Research & Perspectives 3:3, pages e00139.
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Karl-Erik Andersson. 2014. Bladder Dysfunction in the Adult. Bladder Dysfunction in the Adult 121 222 .
Nicola Arrighi, Serena Bodei, Danilo Zani, Martin C. Michel, Claudio Simeone, Sergio Cosciani Cunico, PierFranco Spano & Sandra Sigala. (2013) Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases. Pharmacological Research 74, pages 1-6.
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Karl-Erik Andersson & Alan J. Wein. 2012. Campbell-Walsh Urology. Campbell-Walsh Urology 1967 2002.e14 .
Richard M. Eglen. 2012. Muscarinic Receptors. Muscarinic Receptors 3 28 .
Donald W. Miller, Martha Hinton & Fang Chen. (2011) Evaluation of drug efflux transporter liabilities of darifenacin in cell culture models of the blood-brain and blood-ocular barriers. Neurourology and Urodynamics 30:8, pages 1633-1638.
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Nicola Arrighi, Serena Bodei, Alessandra Lucente, Martin C. Michel, Danilo Zani, Claudio Simeone, Sergio Cosciani Cunico, PierFranco Spano & Sandra Sigala. (2011) Muscarinic receptors stimulate cell proliferation in the human urothelium-derived cell line UROtsa. Pharmacological Research 64:4, pages 420-425.
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A. M. Harrington, C. J. Peck, L. Liu, E. Burcher, J. M. Hutson & B. R. Southwell. (2010) Localization of muscarinic receptors M1R, M2R and M3R in the human colon. Neurogastroenterology & Motility 22:9, pages 999-e263.
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Emily K. Saks & Lily A. Arya. (2009) Pharmacologic Management of Urinary Incontinence, Voiding Dysfunction, and Overactive Bladder. Obstetrics and Gynecology Clinics of North America 36:3, pages 493-507.
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Peter Dwyer, Con Kelleher, Jay Young, François Haab, Karine Lheritier, Rinat Ariely & Ursula Ebinger. (2008) Long‐term benefits of darifenacin treatment for patient quality of life: Results from a 2‐year extension study. Neurourology and Urodynamics 27:6, pages 540-547.
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