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Drug Evaluation

Long-term experience with hylan GF-20 in the treatment of knee osteoarthritis

, MD &
Pages 1797-1804 | Published online: 21 Jun 2008

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Read on this site (3)

Shirley P. Yu & David J. Hunter. (2016) Intra-articular therapies for osteoarthritis. Expert Opinion on Pharmacotherapy 17:15, pages 2057-2071.
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A. J. Cianflocco. (2013) Viscosupplementation in Patients with Osteoarthritis of the Knee. Postgraduate Medicine 125:1, pages 97-105.
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Seiji Saito, Shigeki Momohara, Atsuo Taniguchi & Hisashi Yamanaka. (2009) The intra-articular efficacy of hyaluronate injections in the treatment of rheumatoid arthritis. Modern Rheumatology 19:6, pages 643-651.
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Articles from other publishers (33)

Qirui Chen, Bin Zhou, Hongjun Zhang & Xiaoling Fu. (2023) Hyaluronic acid–gold nano-optical probes and determination of their effect on the inhibition of osteoarthritis progression. Journal of Biomaterials Applications 38:1, pages 64-72.
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Dermot J. Bowden, Stephen J. Eustace & Eoin C. Kavanagh. (2022) The value of injectable viscoelastic supplements for joints. Skeletal Radiology 52:5, pages 933-940.
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M. A. Strakhov, L. I. Alekseeva & K. K. Maremkulov. (2023) Low molecular weight hyaluronates: biological action, efficacy, safety and clinical experience in the treatment of musculoskeletal pain syndromes (literature review and clinical observations). Modern Rheumatology Journal 17:1, pages 93-100.
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Sabreena Aashaq, Asma Rafiq, Iqra Jan, Mehvish Ali, Bilal A. Reshi, Zaffar Amin Shah, Faheem A. Sheikh, Shafquat Majeed & Mushtaq A. Beigh. 2023. Interaction of Nanomaterials With Living Cells. Interaction of Nanomaterials With Living Cells 581 614 .
Wenbin Liu, Mengsi Ma, Zehua Lei, Zixuan Xiong, Tenghui Tao, Pengfei Lei, Yihe Hu, Xulin Jiang & Jun Xiao. (2022) Intra-articular injectable hydroxypropyl chitin/hyaluronic acid hydrogel as bio-lubricant to attenuate osteoarthritis progression. Materials & Design 217, pages 110579.
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Orazio De Lucia, Joerg Jerosch, Sophie Yoon, Tobias Sayre, Wilson Ngai & Georgios Filippou. (2020) One-year efficacy and safety of single or one to three weekly injections of hylan G-F 20 for knee osteoarthritis: a systematic literature review and meta-analysis. Clinical Rheumatology 40:6, pages 2133-2142.
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Maryam Shahi, Daruosh Mohammadnejad, Mohammad Karimipour, Seyed Hossein Rasta, Reza Rahbarghazi & Ali Abedelahi. (2021) Hyaluronic Acid and Regenerative Medicine: New Insights into the Stroke Therapy. Current Molecular Medicine 20:9, pages 675-691.
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Ramesh C. Gupta, Rajiv Lall, Ajay Srivastava & Anita Sinha. (2019) Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory. Frontiers in Veterinary Science 6.
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David A. James, Cullen M. Nigrini, Robert C. Manske & Alexander T. Caughran. 2018. Clinical Orthopaedic Rehabilitation: a Team Approach. Clinical Orthopaedic Rehabilitation: a Team Approach 411 416.e2 .
Rita Grazina, Renato Andrade, Ricardo Bastos, Daniela Costa, Rogério Pereira, José Marinhas, António Maestro & João Espregueira-Mendes. 2018. Osteochondral Tissue Engineering. Osteochondral Tissue Engineering 111 135 .
John C. Cianca & Prathap Jayaram. (2017) Musculoskeletal Injuries and Regenerative Medicine in the Elderly Patient. Physical Medicine and Rehabilitation Clinics of North America 28:4, pages 777-794.
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Soad A. Elsawy, Mona Hamdy & Manal S. Ahmed. (2017) Intra-articular injection of hyaluronic acid for treatment of osteoarthritis knee: comparative study to intra-articular corticosteroids. Egyptian Rheumatology and Rehabilitation 44:4, pages 143-146.
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Yunus Emre Akman, Erhan Sukur, Ahmet Senel, Nur Ece Oztas Sukur, Canan Kelten Talu & Yusuf Ozturkmen. (2017) The comparison of the effects of a novel hydrogel compound and traditional hyaluronate following micro-fracture procedure in a rat full-thickness chondral defect model. Acta Orthopaedica et Traumatologica Turcica 51:4, pages 331-336.
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Erhan Şükür, Canan Talu, Yunus Emre Akman, Esra Çirci, Yusuf Öztürkmen & Tolga Tüzüner. (2016) Comparison of the chondroprotective effect of a novel hydrogel compound and traditional hyaluronate on rat cartilage in a papain-induced osteoarthritis model. Acta Orthopaedica et Traumatologica Turcica 50:4, pages 458-463.
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Jason P. Zlotnicki, Aaron Mares & Volker Musahl. 2016. Endurance Sports Medicine. Endurance Sports Medicine 183 197 .
Taryn E. Ludwig, Miles M. Hunter & Tannin A. Schmidt. (2015) Cartilage boundary lubrication synergism is mediated by hyaluronan concentration and PRG4 concentration and structure. BMC Musculoskeletal Disorders 16:1.
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J. Jerosch. (2015) Injektionsbehandlung mit HyaluronsäureInjection treatment with hyaluronic acid. Zeitschrift für Rheumatologie 74:9, pages 764-773.
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Yves Henrotin, Raghu Raman, Pascal Richette, Hervé Bard, Jörg Jerosch, Thierry Conrozier, Xavier Chevalier & Alberto Migliore. (2015) Consensus statement on viscosupplementation with hyaluronic acid for the management of osteoarthritis. Seminars in Arthritis and Rheumatism 45:2, pages 140-149.
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David J. Hunter. (2015) Viscosupplementation for Osteoarthritis of the Knee. New England Journal of Medicine 372:11, pages 1040-1047.
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Sinéad M. Ryan, Jason McMorrow, Anita Umerska, Hetal B. Patel, Kristin N. Kornerup, Lidia Tajber, Evelyn P. Murphy, Mauro Perretti, Owen I. Corrigan & David J. Brayden. (2013) An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis. Journal of Controlled Release 167:2, pages 120-129.
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Naryana Cristina Mascarin, Rodrigo Luiz Vancini, Marília dos Santos Andrade, Eduardo de Paiva Magalhães, Claudio Andre Barbosa de Lira & Ibsen Bellini Coimbra. (2012) Effects of kinesiotherapy, ultrasound and electrotherapy in management of bilateral knee osteoarthritis: prospective clinical trial. BMC Musculoskeletal Disorders 13:1.
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Paola Brun, Barbara Zavan, Vincenzo Vindigni, Antonella Schiavinato, Assunta Pozzuoli, Claudio Iacobellis & Giovanni Abatangelo. (2012) In vitro response of osteoarthritic chondrocytes and fibroblast-like synoviocytes to a 500-730 kDa hyaluronan amide derivative . Journal of Biomedical Materials Research Part B: Applied Biomaterials 100B:8, pages 2073-2081.
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T. Iannitti, V. Rottigni & B. Palmieri. (2012) A Pilot Study to Compare Two Different Hyaluronic Acid Compounds for Treatment and Knee Osteoarthritis. International Journal of Immunopathology and Pharmacology 25:4, pages 1093-1098.
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Yuanyuan Wang, Stephen Hall, Fahad Hanna, Anita E Wluka, Gail Grant, Paul Marks, Marie Feletar & Flavia M Cicuttini. (2011) Effects of Hylan G-F 20 supplementation on cartilage preservation detected by magnetic resonance imaging in osteoarthritis of the knee: a two-year single-blind clinical trial. BMC Musculoskeletal Disorders 12:1.
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Shimon A. Unterman, Norman A. Marcus & Jennifer H. Elisseeff. 2011. Biodegradable Polymers in Clinical Use and Clinical Development. Biodegradable Polymers in Clinical Use and Clinical Development 631 664 .
Christopher E. Kawcak & C. Wayne McIlwraith. (2011) Comparison of Synovial Fluid in Middle Carpal Joints Undergoing Needle Aspiration, Infusion with Saline, and Infusion with a Combination of N-Acetyl-d-Glucosamine, Hyaluronic Acid, and Sodium Chondroitin Sulfate. Journal of Equine Veterinary Science 31:4, pages 155-159.
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Tommaso Iannitti, Daniele Lodi & Beniamino Palmieri. (2012) Intra-Articular Injections for the Treatment of Osteoarthritis. Drugs in R&D 11:1, pages 13-27.
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H. Collado, L. Bensoussan, J. -M. Viton & A. Delarque. (2011) Place du médecin de médecine physique et de réadaptation dans la prise en charge de la gonarthrose non opéréeContribution of physical and rehabilitation medicine to the non surgical management of knee osteoarthritis. La Lettre de médecine physique et de réadaptation 27:1, pages 9-14.
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Tommaso Iannitti, Daniele Lodi & Beniamino Palmieri. (2012) Intra-Articular Injections for the Treatment of Osteoarthritis. Drugs in R & D 11:1, pages 13-27.
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Robert C. Manske, Cullen M. Nigrini & S. Brent Brotzman. 2011. Clinical Orthopaedic Rehabilitation. Clinical Orthopaedic Rehabilitation 371 392 .
Keith A. Swanson & Mark A. Stratton. 2011. Geriatric Rheumatology. Geriatric Rheumatology 59 71 .
Daniel B. Lyle, Joyce C. Breger, Larissa F. Baeva, Jonathan C. Shallcross, Charles N. Durfor, Nam Sun Wang & John J. Langone. (2010) Low molecular weight hyaluronic acid effects on murine macrophage nitric oxide production. Journal of Biomedical Materials Research Part A 94A:3, pages 893-904.
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James E. Frampton. (2010) Hylan G-F 20 Single-Injection Formulation. Drugs & Aging 27:1, pages 77-85.
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