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Drug Evaluation

Sibutramine: current status as an anti-obesity drug and its future perspectives

, MBBS & , MD
Pages 2161-2173 | Published online: 31 Jul 2008

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Tun-Jen Hsiao, Lawrence Shih-Hsin Wu, Shih-Yi Huang & Eugene Lin. (2010) A common variant in the adiponectin gene on weight loss and body composition under sibutramine therapy in obesity. Clinical Pharmacology: Advances and Applications 2, pages 105-110.
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Victoria Salem & Stephen R Bloom. (2010) Approaches to the pharmacological treatment of obesity. Expert Review of Clinical Pharmacology 3:1, pages 73-88.
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Konstantinos Tziomalos, Gerasimos E Krassas & Themistoklis Tzotzas. (2009) The use of sibutramine in the management of obesity and related disorders: An update. Vascular Health and Risk Management 5, pages 441-452.
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David R Janero & Alexandros Makriyannis. (2009) Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis. Expert Opinion on Emerging Drugs 14:1, pages 43-65.
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Mi Lee, Ji Kim, Jun Choi, Jin Park, Hye Kim, Bo Song, Young Choi, Kyung Kim, Hyunkeun Song & Dae Hwang. (2019) Anti‑obesity effect in high‑fat‑diet‑induced obese C57BL/6 mice: Study of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris. Experimental and Therapeutic Medicine.
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YOON-YOUNG SUNG, TAESOOK YOON, WON-KYUNG YANG, BYEONG-CHEOL MOON & HO KYOUNG KIM. (2013) Anti-obesity effects of Actinidia polygama extract in mice with high-fat diet-induced obesity. Molecular Medicine Reports 7:2, pages 396-400.
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Cecilia Nilsson, Kirsten Raun, Fei-fei Yan, Marianne O Larsen & Mads Tang-Christensen. (2012) Laboratory animals as surrogate models of human obesity. Acta Pharmacologica Sinica 33:2, pages 173-181.
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Hsien-Yuan Lane, Guochuan E. Tsai & Eugene Lin. (2012) Assessing Gene-Gene Interactions in Pharmacogenomics. Molecular Diagnosis & Therapy 16:1, pages 15-27.
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André J. Scheen. (2011) Sibutramine on Cardiovascular Outcome. Diabetes Care 34:Supplement_2, pages S114-S119.
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Sherry Pagoto, Kristin Schneider, Bradley M. Appelhans, Carol Curtin & Alexandra Hajduk. 2011. Psychological Co-morbidities of Physical Illness. Psychological Co-morbidities of Physical Illness 1 72 .
A.J. Scheen. (2010) Cardiovascular Risk-Benefit Profile of Sibutramine. American Journal Cardiovascular Drugs 10:5, pages 321-334.
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André J. Scheen. (2010) Controversy about the Cardiovascular Safety of Sibutramine. Drug Safety 33:7, pages 615-618.
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M. Reiser, S. Eickmann, T. Haverkamp & U. Finckh. (2010) Variegate porphyria in a 46-year-old patient taking sibutramine for weight loss. Obesity Reviews 11:4, pages 329-331.
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Tun-Jen Hsiao, Lawrence Shih-Hsin Wu, Yuchi Hwang, Shih-Yi Huang & Eugene Lin. (2012) Effect of the Common -866G/A Polymorphism of the Uncoupling Protein 2 Gene on Weight Loss and Body Composition under Sibutramine Therapy in an Obese Taiwanese Population. Molecular Diagnosis & Therapy 14:2, pages 101-106.
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K A Kim, W K Song & J Y Park. (2009) Association of CYP2B6, CYP3A5, and CYP2C19 Genetic Polymorphisms With Sibutramine Pharmacokinetics in Healthy Korean Subjects. Clinical Pharmacology & Therapeutics 86:5, pages 511-518.
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Dun-Jen Hsiao, Lawrence Shih-Hsin Wu, Shih-Yi Huang & Eugene Lin. (2009) Weight loss and body fat reduction under sibutramine therapy in obesity with the C825T polymorphism in the GNB3 gene. Pharmacogenetics and Genomics 19:9, pages 730-733.
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