411
Views
36
CrossRef citations to date
0
Altmetric
Reviews

The good, the bad and the ugly: how altered peptide ligands modulate immunity

, , &
Pages 1873-1884 | Published online: 06 Nov 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Jintian He, Huiqi Li, Chao Liu, Gaizhen Wang, Lan Ge, Shufen Ma, Lijing Huang, Shaofeng Yan & Xiaohong Xu. (2015) Formulation and evaluation of poly(lactic-co-glycolic acid) microspheres loaded with an altered collagen type II peptide for the treatment of rheumatoid arthritis. Journal of Microencapsulation 32:6, pages 608-617.
Read now
N. Lorenzo, A. Barberá, M. C. Domínguez, A. M. Torres, M. V. Hernandez, I. Hernandez, R. Gil, J. Ancizar, H. Garay, O. Reyes, F. Altruda, L. Silengo & G. Padrón. (2012) Therapeutic effect of an altered peptide ligand derived from heat-shock protein 60 by suppressing of inflammatory cytokines secretion in two animal models of rheumatoid arthritis. Autoimmunity 45:6, pages 449-459.
Read now

Articles from other publishers (34)

Sikai Wang, Guanglei Li, Xiongjie Liang, Zexuan Wu, Chao Chen, Fawang Zhang, Jiawen Niu, Xuefeng Li, Jinglong Yan, Nanxiang Wang, Jing Li & Yufu Wang. (2023) Small Extracellular Vesicles Derived from Altered Peptide Ligand‐Loaded Dendritic Cell Act as A Therapeutic Vaccine for Spinal Cord Injury Through Eliciting CD4 + T cell‐Mediated Neuroprotective Immunity . Advanced Science.
Crossref
Lixin Yin, Yang Zhou, Sheng Hong, Feiqing Ding & Hui Cai. (2023) Strategies for Synthesizing and Enhancing the Immune Response of Cancer Vaccines Based on MUC1 Glycopeptide Antigens. ChemBioChem 24:10.
Crossref
Lena Immisch, George Papafotiou, Nerea Gallarín Delgado, Vivian Scheuplein, Annette Paschen, Thomas Blankenstein & Gerald Willimsky. (2023) Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors. Frontiers in Immunology 14.
Crossref
Sandeep Kumar Dhanda, Jitendra Malviya & Sudheer Gupta. (2022) Not all T cell epitopes are equally desired: a review of in silico tools for the prediction of cytokine-inducing potential of T-cell epitopes . Briefings in Bioinformatics 23:5.
Crossref
Alicia Asín, Fayna García-Martín, Jesús Hector Busto, Alberto Avenoza, Jesús Manuel Peregrina & Francisco Corzana. (2022) Structure-based Design of Anti-cancer Vaccines: The Significance of Antigen Presentation to Boost the Immune Response. Current Medicinal Chemistry 29:7, pages 1258-1270.
Crossref
Meng Li, Arata Itoh, Jingchao Xi, Chunsong Yu, Yuehong Wu, William M. Ridgway & Haipeng Liu. (2021) Enhancing Antigen Presentation and Inducing Antigen-Specific Immune Tolerance with Amphiphilic Peptides. The Journal of Immunology 207:8, pages 2051-2059.
Crossref
Cody D. Moorman, Sue J. Sohn & Hyewon Phee. (2021) Emerging Therapeutics for Immune Tolerance: Tolerogenic Vaccines, T cell Therapy, and IL-2 Therapy. Frontiers in Immunology 12.
Crossref
Vasso Apostolopoulos, Joanna Bojarska, Tsun-Thai Chai, Sherif Elnagdy, Krzysztof Kaczmarek, John Matsoukas, Roger New, Keykavous Parang, Octavio Paredes Lopez, Hamideh Parhiz, Conrad O. Perera, Monica Pickholz, Milan Remko, Michele Saviano, Mariusz Skwarczynski, Yefeng Tang, Wojciech M. Wolf, Taku Yoshiya, Janusz Zabrocki, Piotr Zielenkiewicz, Maha AlKhazindar, Vanessa Barriga, Konstantinos Kelaidonis, Elham Mousavinezhad Sarasia & Istvan Toth. (2021) A Global Review on Short Peptides: Frontiers and Perspectives. Molecules 26:2, pages 430.
Crossref
Chanchal Kumar, Rajat Pratap Singh, Mrigendra Kumar Dwiwedi & Ajay Amit. 2021. Colon Cancer Diagnosis and Therapy. Colon Cancer Diagnosis and Therapy 271 308 .
Efstathios Deskoulidis, Souzana Petrouli, Vasso Apostolopoulos, John Matsoukas & Emmanuel Topoglidis. (2020) The Use of Electrochemical Voltammetric Techniques and High-Pressure Liquid Chromatography to Evaluate Conjugation Efficiency of Multiple Sclerosis Peptide-Carrier Conjugates. Brain Sciences 10:9, pages 577.
Crossref
Kirsty L. Wilson, Sue D. Xiang & Magdalena Plebanski. (2020) Functional Recognition by CD8+ T Cells of Epitopes with Amino Acid Variations Outside Known MHC Anchor or T Cell Receptor Recognition Residues. International Journal of Molecular Sciences 21:13, pages 4700.
Crossref
Songlin Zhang, Jian Chen, Peijian Hong, Jinru Li, Yi Tian, Yuzhang Wu & Shufeng Wang. (2020) PromPDD, a web-based tool for the prediction, deciphering and design of promiscuous peptides that bind to HLA class I molecules. Journal of Immunological Methods 476, pages 112685.
Crossref
Neeraja Punde, Jennifer Kooken, Dagmar Leary, Patricia M. Legler & Evelina Angov. (2019) Codon harmonization reduces amino acid misincorporation in bacterially expressed P. falciparum proteins and improves their immunogenicity. AMB Express 9:1.
Crossref
Marco Daniele Parenti, Aurelia Santoro, Alberto Del Rio & Claudio Franceschi. (2019) Literature review in support of adjuvanticity/immunogenicity assessment of proteins. EFSA Supporting Publications 16:1.
Crossref
Daniel Meister, S. Maryamdokht Taimoory & John F. Trant. (2019) Unnatural amino acids improve affinity and modulate immunogenicity: Developing peptides to treat MHC type II autoimmune disorders. Peptide Science 111:1, pages e24058.
Crossref
George Deraos, Eftichia Kritsi, Minos-Timotheos Matsoukas, Konstantina Christopoulou, Hubert Kalbacher, Panagiotis Zoumpoulakis, Vasso Apostolopoulos & John Matsoukas. (2018) Design of Linear and Cyclic Mutant Analogues of Dirucotide Peptide (MBP82–98) against Multiple Sclerosis: Conformational and Binding Studies to MHC Class II. Brain Sciences 8:12, pages 213.
Crossref
Chunsong Yu & Haipeng Liu. 2018. Immunoregulatory Aspects of Immunotherapy. Immunoregulatory Aspects of Immunotherapy.
Athanasios Lourbopoulos, Minos-Timotheos Matsoukas, Maria Katsara, George Deraos, Aggeliki Giannakopoulou, Roza Lagoudaki, Nikolaos Grigoriadis, John Matsoukas & Vasso Apostolopoulos. (2018) Cyclization of PLP139-151 peptide reduces its encephalitogenic potential in experimental autoimmune encephalomyelitis. Bioorganic & Medicinal Chemistry 26:9, pages 2221-2228.
Crossref
Athanasios Lourbopoulos, George Deraos, Minos-Timotheos Matsoukas, Olga Touloumi, Aggeliki Giannakopoulou, Hubert Kalbacher, Nikolaos Grigoriadis, Vasso Apostolopoulos & John Matsoukas. (2017) Cyclic MOG 35 – 55 ameliorates clinical and neuropathological features of experimental autoimmune encephalomyelitis. Bioorganic & Medicinal Chemistry 25:15, pages 4163-4174.
Crossref
Narges Dargahi, Maria Katsara, Theodore Tselios, Maria-Eleni Androutsou, Maximilian de Courten, John Matsoukas & Vasso Apostolopoulos. (2017) Multiple Sclerosis: Immunopathology and Treatment Update. Brain Sciences 7:12, pages 78.
Crossref
Mary-Patricia Yannakakis, Carmen Simal, Haralambos Tzoupis, Maria Rodi, Narges Dargahi, Monica Prakash, Athanasia Mouzaki, James Platts, Vasso Apostolopoulos & Theodore Tselios. (2017) Design and Synthesis of Non-Peptide Mimetics Mapping the Immunodominant Myelin Basic Protein (MBP83–96) Epitope to Function as T-Cell Receptor Antagonists. International Journal of Molecular Sciences 18:6, pages 1215.
Crossref
Shayla K. Shorter, Frederick J. Schnell, Sean R. McMaster, David F. Pinelli, Rakieb Andargachew & Brian D. Evavold. (2016) Viral Escape Mutant Epitope Maintains TCR Affinity for Antigen yet Curtails CD8 T Cell Responses. PLOS ONE 11:2, pages e0149582.
Crossref
Chamini J Perera, Samuel S Duffy, Justin G Lees, Cristina F Kim, Barbara Cameron, Vasso Apostolopoulos & Gila Moalem-Taylor. (2015) Active immunization with myelin-derived altered peptide ligand reduces mechanical pain hypersensitivity following peripheral nerve injury. Journal of Neuroinflammation 12:1.
Crossref
Sue D. Xiang, Qian Gao, Kirsty L. Wilson, Arne Heyerick & Magdalena Plebanski. (2015) Mapping T and B cell epitopes in sperm protein 17 to support the development of an ovarian cancer vaccine. Vaccine 33:44, pages 5950-5959.
Crossref
Chamini J. Perera, Justin G. Lees, Samuel S. Duffy, Preet G.S. Makker, Brett Fivelman, Vasso Apostolopoulos & Gila Moalem-Taylor. (2015) Effects of active immunisation with myelin basic protein and myelin-derived altered peptide ligand on pain hypersensitivity and neuroinflammation. Journal of Neuroimmunology 286, pages 59-70.
Crossref
Graham Leggatt. (2014) Peptide Dose and/or Structure in Vaccines as a Determinant of T Cell Responses. Vaccines 2:3, pages 537-548.
Crossref
Heath A. Smith, Brian T. Rekoske & Douglas G. McNeel. (2014) DNA vaccines encoding altered peptide ligands for SSX2 enhance epitope-specific CD8+ T-cell immune responses. Vaccine 32:15, pages 1707-1715.
Crossref
Vasso Apostolopoulos, Theresia Thalhammer, Andreas G. Tzakos & Lily Stojanovska. (2013) Targeting Antigens to Dendritic Cell Receptors for Vaccine Development. Journal of Drug Delivery 2013, pages 1-22.
Crossref
Jonathan D. Buhrman & Jill E. Slansky. (2012) Improving T cell responses to modified peptides in tumor vaccines. Immunologic Research 55:1-3, pages 34-47.
Crossref
Keun-Ok Jung, Asif M. Khan, Benjamin Yong Liang Tan, Yongli Hu, Gregory G. Simon, Eduardo J. M. Nascimento, Francois Lemonnier, Vladimir Brusic, Olivo Miotto, Tin Wee Tan, Ernesto T. A. Marques, Rafael Dhalia, Jerome Salmon & J. Thomas August. (2012) West Nile Virus T-Cell Ligand Sequences Shared with Other Flaviviruses: a Multitude of Variant Sequences as Potential Altered Peptide Ligands. Journal of Virology 86:14, pages 7616-7624.
Crossref
Matthias Höhne & Uwe T. Bornscheuer. 2012. Enzyme Catalysis in Organic Synthesis. Enzyme Catalysis in Organic Synthesis 779 820 .
Michael D. Valentino, C. Siddiq Abdul-Alim, Zachary J. Maben, Denise Skrombolas, Lucinda L. Hensley, Thomas H. Kawula, Michelle Dziejman, Edith M. Lord, Jeffrey A. Frelinger & John G. Frelinger. (2011) A broadly applicable approach to T cell epitope identification: Application to improving tumor associated epitopes and identifying epitopes in complex pathogens. Journal of Immunological Methods 373:1-2, pages 111-126.
Crossref
Colleen E. Hayes, Faye E. Nashold, Christopher G. Mayne, Justin A. Spanier & Corwin D. Nelson. 2011. Vitamin D. Vitamin D 1843 1877 .
Rebecca M. Ream, Jie Sun & Thomas J. Braciale. (2010) Stimulation of Naive CD8+ T Cells by a Variant Viral Epitope Induces Activation and Enhanced Apoptosis. The Journal of Immunology 184:5, pages 2401-2409.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.