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From lab to bedside: emerging clinical applications of thymosin α1

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Pages 593-608 | Published online: 24 Apr 2009

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Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Najmeh Parvin, Ahmad Gholami, Seeram Ramakrishna, Navid Omidifar, Mohsen Moghadami, Wei-Hung Chiang & Sargol Mazraedoost. (2021) Recent biotechnological approaches for treatment of novel COVID-19: from bench to clinical trial. Drug Metabolism Reviews 53:1, pages 141-170.
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Muhammad Shahbaz Aslam, Iram Gull, Malik Siddique Mahmood, Muhammad Mudassir Iqbal, Zaigham Abbas, Imran Tipu, Aftab Ahmed & Muhammad Amin Athar. (2020) High yield expression, characterization, and biological activity of IFNα2-Tα1 fusion protein. Preparative Biochemistry & Biotechnology 50:3, pages 281-291.
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Sujun Sun, Haiyu Ji, Yingying Feng, Yu Kang, Juan Yu & Anjun Liu. (2018) A novel mechanism of tumor-induced thymic atrophy in mice bearing H22 hepatocellular carcinoma. Cancer Management and Research 10, pages 417-424.
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Enrico Garaci. (2018) From thymus to cystic fibrosis: the amazing life of thymosin alpha 1. Expert Opinion on Biological Therapy 18:sup1, pages 9-11.
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Claudia Stincardini, Giorgia Renga, Valeria Villella, Marilena Pariano, Vasilis Oikonomou, Monica Borghi, Marina M. Bellet, Luigi Sforna, Claudio Costantini, Allan L. Goldstein, Enrico Garaci & Luigina Romani. (2018) Cellular proteostasis: a new twist in the action of thymosin α1. Expert Opinion on Biological Therapy 18:sup1, pages 43-48.
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Claudia Matteucci, Ayele Argaw-Denboba, Emanuela Balestrieri, Alessandro Giovinazzo, Martino Miele, Cartesio D’Agostini, Francesca Pica, Sandro Grelli, Maurizio Paci, Antonio Mastino, Paola Sinibaldi Vallebona, Enrico Garaci & Carlo Tomino. (2018) Deciphering cellular biological processes to clinical application: a new perspective for Tα1 treatment targeting multiple diseases. Expert Opinion on Biological Therapy 18:sup1, pages 23-31.
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Francesca Pica, Roberta Gaziano, Ida Antonia Casalinuovo, Gabriella Moroni, Cristina Buè, Dolores Limongi, Cartesio D’Agostini, Carlo Tomino, Roberto Perricone, Anna Teresa Palamara, Paola Sinibaldi Vallebona & Enrico Garaci. (2018) Serum thymosin alpha 1 levels in normal and pathological conditions. Expert Opinion on Biological Therapy 18:sup1, pages 13-21.
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Walter Mandaliti, Ridvan Nepravishta, Francesca Pica, Paola Sinibaldi Vallebona, Enrico Garaci & Maurizio Paci. (2018) Potential mechanism of thymosin-α1-membrane interactions leading to pleiotropy: experimental evidence and hypotheses. Expert Opinion on Biological Therapy 18:sup1, pages 33-42.
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Xiaoning Wu, Yiwen Shi, Jialing Zhou, Yameng Sun, Hongxin Piao, Wei Jiang, Anlin Ma, Yongpeng Chen, Mingyi Xu, Wen Xie, Jun Cheng, Shibin Xie, Jia Shang, Jilin Cheng, Qing Xie, Huiguo Ding, Xuqing Zhang, Lang Bai, Mingxiang Zhang, Bingqiong Wang, Shuyan Chen, Hong Ma, Xiaojuan Ou, Jidong Jia & Hong You. (2018) Combination of entecavir with thymosin alpha-1 in HBV-related compensated cirrhosis: a prospective multicenter randomized open-label study. Expert Opinion on Biological Therapy 18:sup1, pages 61-69.
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Wilfried Posch, Marion Steger, Doris Wilflingseder & Cornelia Lass-Flörl. (2017) Promising immunotherapy against fungal diseases. Expert Opinion on Biological Therapy 17:7, pages 861-870.
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Silvia Moretti, Vasileios Oikonomou, Enrico Garaci & Luigina Romani. (2015) Thymosin α1: burying secrets in the thymus. Expert Opinion on Biological Therapy 15:sup1, pages 51-58.
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Claudia Matteucci, Antonella Minutolo, Michela Pollicita, Emanuela Balestrieri, Sandro Grelli, Gabriella D’Ettorre, Vincenzo Vullo, Ilaria Bucci, Alessandra Luchini, Stefano Aquaro, Paola Sinibaldi-Vallebona, Beatrice Macchi, Carlo Federico Perno, Antonio Mastino & Enrico Garaci. (2015) Thymosin α 1 potentiates the release by CD8+ cells of soluble factors able to inhibit HIV-1 and human T lymphotropic virus 1 infection in vitro. Expert Opinion on Biological Therapy 15:sup1, pages 83-100.
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Enrico Garaci, Francesca Pica, Claudia Matteucci, Roberta Gaziano, Cartesio D’Agostini, Martino Tony Miele, Roberto Camerini, Anna Teresa Palamara, Cartesio Favalli, Antonio Mastino, Annalucia Serafino & Paola Sinibaldi Vallebona. (2015) Historical review on thymosin α1 in oncology: preclinical and clinical experiences. Expert Opinion on Biological Therapy 15:sup1, pages 31-39.
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Allan L Goldstein & Hynda K Kleinman. (2015) Advances in the basic and clinical applications of thymosin β4. Expert Opinion on Biological Therapy 15:sup1, pages 139-145.
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Ridvan Nepravishta, Walter Mandaliti, Tommaso Eliseo, Paola Sinibaldi Vallebona, Francesca Pica, Enrico Garaci & Maurizio Paci. (2015) Thymosin α1 inserts N terminus into model membranes assuming a helical conformation. Expert Opinion on Biological Therapy 15:sup1, pages 71-81.
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Robert S King & Cynthia Tuthill. (2015) Evaluation of thymosin α 1 in nonclinical models of the immune-suppressing indications melanoma and sepsis. Expert Opinion on Biological Therapy 15:sup1, pages 41-49.
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Xiaoning Wu, Jidong Jia & Hong You. (2015) Thymosin alpha-1 treatment in chronic hepatitis B. Expert Opinion on Biological Therapy 15:sup1, pages 129-132.
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Ben Morton, Shaun Harry Pennington & Stephen B Gordon. (2014) Immunomodulatory adjuvant therapy in severe community-acquired pneumonia. Expert Review of Respiratory Medicine 8:5, pages 587-596.
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