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Overview of stem cell therapy for Crohn's disease

, MD MSPH
Pages 841-847 | Published online: 15 Jun 2009

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Richard Cuthbert, Sally A Boxall, Hiang Boon Tan, Peter V. Giannoudis, Dennis McGonagle & Elena Jones. (2012) Single-platform quality control assay to quantify multipotential stromal cells in bone marrow aspirates prior to bulk manufacture or direct therapeutic use. Cytotherapy 14:4, pages 431-440.
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Margit Zeher, Gabor Papp & Peter Szodoray. (2011) Autologous haemopoietic stem cell transplantation for autoimmune diseases. Expert Opinion on Biological Therapy 11:9, pages 1193-1201.
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Soo Jeong Choi, Jin Kuk Kim & Seung Duk Hwang. (2010) Mesenchymal stem cell therapy for chronic renal failure. Expert Opinion on Biological Therapy 10:8, pages 1217-1226.
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Damian García-Olmo & Mariano Garcia-Arranz. The history of Crohn’s perianal fistula treatment with mesenchymal stem cells: the story of darvadstrocel. Expert Opinion on Biological Therapy 0:0, pages 1-6.
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Articles from other publishers (34)

Bushu Harna, Pulkit Kalra, Shivali Arya, Naveen Jeyaraman, Arulkumar Nallakumarasamy, Madhan Jeyaraman, Ramya Lakshmi Rajendran, Eun Jung Oh, Manish Khanna, Uma Maheswari Rajendran, Ho Yun Chung, Byeong-Cheol Ahn & Prakash Gangadaran. (2023) Mesenchymal stromal cell therapy for patients with rheumatoid arthritis. Experimental Cell Research 423:1, pages 113468.
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Won Hee Kim, Jun Hwan Yoo, In Kyung Yoo, Chang Il Kwon & Sung Pyo Hong. (2023) Effects of Mesenchymal Stem Cells Treatment on Radiation-Induced Proctitis in Rats. Yonsei Medical Journal 64:3, pages 167.
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D. D. Kazarin, M. S. Chupina & A. E. Shklyaev. (2022) Predictors of the efficacy of infliximab in patients with ulcerative colitis. Meditsinskiy sovet = Medical Council:15, pages 128-133.
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Qin Chen, Yufei Li, Xiaofeng Wang & Huashan Li. (2020) Hot topics in global perianal fistula research. Medicine 99:17, pages e19659.
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Difeng Fang & Jinfang Zhu. (2019) Molecular switches for regulating the differentiation of inflammatory and IL-10-producing anti-inflammatory T-helper cells. Cellular and Molecular Life Sciences 77:2, pages 289-303.
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Venera Rakhmetova & Aida Orazbayeva. (2017) Stem cells therapy in inflammatory bowel disease. Journal of Clinical Medicine of Kazakhstan 4:46, pages 6-10.
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Andrea L. DiCarlo, Radia Tamarat, Carmen I. Rios, Marc Benderitter, Christine W. Czarniecki, Theresa C. Allio, Francesca Macchiarini, Bert W. Maidment & Jean-Rene Jourdain. (2017) Cellular Therapies for Treatment of Radiation Injury: Report from a NIH/NIAID and IRSN Workshop. Radiation Research 188:2, pages e54-e75.
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Margit Zeher, Gábor Papp, Britt Nakken & Peter Szodoray. (2017) Hematopoietic stem cell transplantation in autoimmune disorders: From immune-regulatory processes to clinical implications. Autoimmunity Reviews 16:8, pages 817-825.
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Valeria Messina, Carla Buccione, Giulia Marotta, Giovanna Ziccheddu, Michele Signore, Gianfranco Mattia, Rossella Puglisi, Benedetto Sacchetti, Livia Biancone & Mauro Valtieri. (2017) Gut Mesenchymal Stromal Cells in Immunity. Stem Cells International 2017, pages 1-6.
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Kang Chao, Shenghong Zhang, Yun Qiu, Xiaoyong Chen, Xiaoran Zhang, Chuang Cai, Yanwen Peng, Ren Mao, Meirav Pevsner-Fischer, Shomron Ben-horin, Eran Elinav, Zhirong Zeng, Baili Chen, Yao He, Andy Peng Xiang & Minhu Chen. (2016) Human umbilical cord-derived mesenchymal stem cells protect against experimental colitis via CD5+ B regulatory cells. Stem Cell Research & Therapy 7:1.
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Elena Jones & Richard Schäfer. 2015. Stem Cell Protocols. Stem Cell Protocols 105 120 .
O. V. Knyazev, A. I. Parfenov, P. L. Shcherbakov, I. N. Ruchkina & A. G. Konoplyannikov. (2013) Cell Therapy of Refractory Crohn?s Disease. Bulletin of Experimental Biology and Medicine 156:1, pages 139-145.
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Jan Voswinkel, Sabine Francois, Jean-Marc Simon, Marc Benderitter, Norbert-Claude Gorin, Mohamad Mohty, Loïc Fouillard & Alain Chapel. (2013) Use of Mesenchymal Stem Cells (MSC) in Chronic Inflammatory Fistulizing and Fibrotic Diseases: a Comprehensive Review. Clinical Reviews in Allergy & Immunology 45:2, pages 180-192.
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Jan Voswinkel, Sabine Francois, Norbert-Claude Gorin & Alain Chapel. (2013) Gastro-intestinal autoimmunity: preclinical experiences and successful therapy of fistulizing bowel diseases and gut Graft versus host disease by mesenchymal stromal cells. Immunologic Research 56:2-3, pages 241-248.
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Silvia SelleriMame Massar DiengSimon NicolettiIsabelle LouisChristian BeausejourFrançoise Le DeistElie Haddad. (2013) Cord-Blood-Derived Mesenchymal Stromal Cells Downmodulate CD4 + T-Cell Activation by Inducing IL-10-Producing Th1 Cells . Stem Cells and Development 22:7, pages 1063-1075.
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Alain Chapel. (2013) New insights for pelvic radiation disease treatment: Multipotent stromal cell is a promise mainstay treatment for the restoration of abdominopelvic severe chronic damages induced by radiotherapy. World Journal of Stem Cells 5:4, pages 106.
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Jacobo Trebol Lopez, Tihomir Georgiev-Hristov, Mariano García-Arranz & Damián García-Olmo. 2013. Regenerative Medicine and Cell Therapy. Regenerative Medicine and Cell Therapy 245 277 .
Sabine Schu, Mikhail Nosov, Lisa O'Flynn, Georgina Shaw, Oliver Treacy, Frank Barry, Mary Murphy, Timothy O'Brien & Thomas Ritter. (2012) Immunogenicity of allogeneic mesenchymal stem cells. Journal of Cellular and Molecular Medicine 16:9, pages 2094-2103.
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Bing Huang, Yasuhiko Tabata & Jian-Qing Gao. (2012) Mesenchymal stem cells as therapeutic agents and potential targeted gene delivery vehicle for brain diseases. Journal of Controlled Release 162:2, pages 464-473.
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Michele Signore, Anna Maria Cerio, Alessandra Boe, Alfredo Pagliuca, Valentina Zaottini, Ilaria Schiavoni, Giorgio Fedele, Stefano Petti, Simone Navarra, Clara Maria Ausiello, Elvira Pelosi, Alessandro Fatica, Antonio Sorrentino & Mauro Valtieri. (2012) Identity and ranking of colonic mesenchymal stromal cells. Journal of Cellular Physiology 227:9, pages 3291-3300.
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N.E. Timmins, M. Kiel, M. Günther, C. Heazlewood, M.R. Doran, G. Brooke & K. Atkinson. (2012) Closed system isolation and scalable expansion of human placental mesenchymal stem cells. Biotechnology and Bioengineering 109:7, pages 1817-1826.
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Scott D. Olson, Kari Pollock, Amal Kambal, Whitney Cary, Gaela-Marie Mitchell, Jeremy Tempkin, Heather Stewart, Jeannine McGee, Gerhard Bauer, Hyun Sook Kim, Teresa Tempkin, Vicki Wheelock, Geralyn Annett, Gary Dunbar & Jan A. Nolta. (2011) Genetically Engineered Mesenchymal Stem Cells as a Proposed Therapeutic for Huntington’s Disease. Molecular Neurobiology 45:1, pages 87-98.
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Obinna O. Adibe & Keith E. Georgeson. 2012. Pediatric Surgery. Pediatric Surgery 1209 1215 .
Lu Liang, Chunlan Dong, Xiaojun Chen, Zhihong Fang, Jie Xu, Meng Liu, Xiaoguang Zhang, Dong Sheng Gu, Ding Wang, Weiting Du, Delin Zhu & Zhong Chao Han. (2011) Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Mice Trinitrobenzene Sulfonic Acid (TNBS)-Induced Colitis. Cell Transplantation 20:9, pages 1395-1408.
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Jacobo Trebol LopezTihomir Georgiev HristovMariano García-ArranzDamián García-Olmo. (2011) Stem Cell Therapy for Digestive Tract Diseases: Current State and Future Perspectives. Stem Cells and Development 20:7, pages 1113-1129.
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Brent R. Weil, Mariuxi C. Manukyan, Jeremy L. Herrmann, Aaron M. Abarbanell, Jeffrey A. Poynter, Yue Wang & Daniel R. Meldrum. (2011) The Immunomodulatory Properties of Mesenchymal Stem Cells: Implications for Surgical Disease. Journal of Surgical Research 167:1, pages 78-86.
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Junxia Lei, Zhen Wang, Dayang Hui, Weihua Yu, Dunhua Zhou, Wenjie Xia, Chun Chen, Qunzhou Zhang, Zhichong Wang, Qi Zhang & Andy Peng Xiang. (2011) Ligation of TLR2 and TLR4 on murine bone marrow-derived mesenchymal stem cells triggers differential effects on their immunosuppressive activity. Cellular Immunology 271:1, pages 147-156.
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Martin J Hoogduijn, Felix Popp, Richard Verbeek, Mojgan Masoodi, Anna Nicolaou, Carla Baan & Marc-H Dahlke. (2010) The immunomodulatory properties of mesenchymal stem cells and their use for immunotherapy. International Immunopharmacology 10:12, pages 1496-1500.
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Christophe Martinaud, Cédric Thepenier, Marina Trouillas, Juliette Peltzer, Georges Uzan, Marie-Caroline Le Bousse Kerdilès, Marie Prat & Jean-Jacques Lataillade. (2010) Les cellules souches mésenchymateuses : des cellules pour la médecine régénérative du futur ?. Revue Francophone des Laboratoires 2010:427, pages 47-59.
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Christelle P. El-Haibi & Antoine E. Karnoub. (2010) Mesenchymal Stem Cells in the Pathogenesis and Therapy of Breast Cancer. Journal of Mammary Gland Biology and Neoplasia 15:4, pages 399-409.
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Alain Vertès. 2010. The Delivery of Regenerative Medicines and Their Impact on Healthcare. The Delivery of Regenerative Medicines and Their Impact on Healthcare 153 175 .
Nanette Joyce, Geralyn Annett, Louisa Wirthlin, Scott Olson, Gerhard Bauer & Jan A Nolta. (2010) Mesenchymal stem cells for the treatment of neurodegenerative disease. Regenerative Medicine 5:6, pages 933-946.
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Alan Tyndall. (2010) Mesenchymal stem cells for multiple sclerosis: can we find the answer?. Multiple Sclerosis Journal 16:4, pages 386-386.
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Thomas E. Ichim, Robert J. Harman, Wei-Ping Min, Boris Minev, Fabio Solano, Jorge Paz Rodriguez, Doru T. Alexandrescu, Rosalia De Necochea-Campion, Xiang Hu, Annette M. Marleau & Neil H. Riordan. (2010) Autologous stromal vascular fraction cells: A tool for facilitating tolerance in rheumatic disease. Cellular Immunology 264:1, pages 7-17.
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