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Reovirus-based therapy for cancer

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Pages 817-830 | Published online: 15 Jun 2009

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Rita Mendes, Bárbara Carreira, Pedro V. Baptista & Alexandra R. Fernandes. (2016) Non-small cell lung cancer biomarkers and targeted therapy - two faces of the same coin fostered by nanotechnology. Expert Review of Precision Medicine and Drug Development 1:2, pages 155-168.
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Jonathan Pol, Norma Bloy, Florine Obrist, Alexander Eggermont, Jérôme Galon, Isabelle Cremer, Philippe Erbs, Jean-Marc Limacher, Xavier Preville, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi. (2014) Trial Watch:. OncoImmunology 3:6.
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Erika Vacchelli, Alexander Eggermont, Catherine Sautès-Fridman, Jérôme Galon, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi. (2013) Trial watch. OncoImmunology 2:6.
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Jonathan G Pol, Julien Rességuier & Brian D Lichty. (2012) Oncolytic viruses: a step into cancer immunotherapy. Virus Adaptation and Treatment 4, pages 1-21.
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Diana JM Van Den Wollenberg, Sanne K Van Den Hengel, Iris JC Dautzenberg, Onno Kranenburg & Rob C Hoeben. (2009) Modification of mammalian reoviruses for use as oncolytic agents. Expert Opinion on Biological Therapy 9:12, pages 1509-1520.
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Madison Rice, Esmerina Tili, Houra Loghmani & Gerard J. Nuovo. (2023) The differential expression of toll like receptors and RIG-1 correlates to the severity of infectious diseases. Annals of Diagnostic Pathology 63, pages 152102.
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Pooja Saxena. 2022. Bionanotechnology: Next-Generation Therapeutic Tools. Bionanotechnology: Next-Generation Therapeutic Tools 30 48 .
Namita Mahadik, Dwaipayan Bhattacharya, Akshaya Padmanabhan, Kalyani Sakhare, Kumar Pranav Narayan & Rajkumar Banerjee. (2021) Targeting steroid hormone receptors for anti‐cancer therapy—A review on small molecules and nanotherapeutic approaches. WIREs Nanomedicine and Nanobiotechnology 14:2.
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Maria Terrível, Catarina Gromicho & Ana Miguel Matos. (2020) Oncolytic viruses: what to expect from their use in cancer treatment. Microbiology and Immunology 64:7, pages 477-492.
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Yuki Katayama, Masashi Tachibana, Nozomi Kurisu, Yukako Oya, Yuichi Terasawa, Hiroshi Goda, Kouji Kobiyama, Ken J. Ishii, Shizuo Akira, Hiroyuki Mizuguchi & Fuminori Sakurai. (2018) Oncolytic Reovirus Inhibits Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in a TLR3-Dependent Manner. The Journal of Immunology 200:8, pages 2987-2999.
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Delphine Lanoie & Guy Lemay. (2018) Multiple proteins differing between laboratory stocks of mammalian orthoreoviruses affect both virus sensitivity to interferon and induction of interferon production during infection. Virus Research 247, pages 40-46.
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Yusuke Inagaki, Eiji Kubota, Yoshinori Mori, Mineyoshi Aoyama, Hiromi Kataoka, Randal N. Johnston & Takashi Joh. (2017) Anti-tumor efficacy of oncolytic reovirus against gastrointestinal stromal tumor cells. Oncotarget 8:70, pages 115632-115646.
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Jennifer S. Carew, Claudia M. Espitia, Weiguo Zhao, Monica M. Mita, Alain C. Mita & Steffan T. Nawrocki. (2017) Oncolytic reovirus inhibits angiogenesis through induction of CXCL10/IP-10 and abrogation of HIF activity in soft tissue sarcomas. Oncotarget 8:49, pages 86769-86783.
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Kai Li, Jiankai Liang, Yuan Lin, Haipeng Zhang, Xiao Xiao, Yaqian Tan, Jing Cai, Wenbo Zhu, Fan Xing, Jun Hu & Guangmei Yan. (2016) A classical PKA inhibitor increases the oncolytic effect of M1 virus via activation of exchange protein directly activated by cAMP 1. Oncotarget 7:30, pages 48443-48455.
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Jun Gong, Esha Sachdev, Alain C Mita & Monica M Mita. (2016) Clinical development of reovirus for cancer therapy: An oncolytic virus with immune-mediated antitumor activity. World Journal of Methodology 6:1, pages 25.
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A. Tsun, X. N. Miao, C. M. Wang & D. C. Yu. 2016. Progress in Cancer Immunotherapy. Progress in Cancer Immunotherapy 241 283 .
Kevin R. Kelly, Claudia M. Espitia, Weiguo Zhao, Erik Wendlandt, Guido Tricot, Fenghuang Zhan, Jennifer S. Carew & Steffan T. Nawrocki. (2015) Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus. Oncotarget 6:38, pages 41275-41289.
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Devalingam Mahalingam, Sukeshi Patel, Gerard Nuovo, George Gill, Giovanni Selvaggi, Matt Coffey & Steffan T. Nawrocki. (2015) The combination of intravenous Reolysin and gemcitabine induces reovirus replication and endoplasmic reticular stress in a patient with KRAS-activated pancreatic cancer. BMC Cancer 15:1.
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D.G. Roy, A.T. Power, M.C. Bourgeois-Daigneault, T. Falls, L. Ferreira, A. Stern, C. Tanese de Souza, J.A. McCart, D.F. Stojdl, B.D. Lichty, H. Atkins, R.C. Auer, J.C. Bell & F. Le Boeuf. (2015) Programmable insect cell carriers for systemic delivery of integrated cancer biotherapy. Journal of Controlled Release 220, pages 210-221.
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Véronique Sandekian & Guy Lemay. (2015) A single amino acid substitution in the mRNA capping enzyme λ2 of a mammalian orthoreovirus mutant increases interferon sensitivity. Virology 483, pages 229-235.
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Romit Chakrabarty, Hue Tran, Giovanni Selvaggi, Allison Hagerman, Brad Thompson & Matt Coffey. (2015) The oncolytic virus, pelareorep, as a novel anticancer agent: a review. Investigational New Drugs 33:3, pages 761-774.
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Takuma Hotani, Masashi Tachibana, Hiroyuki Mizuguchi & Fuminori Sakurai. (2015) Reovirus double-stranded RNA genomes and polyI:C induce down-regulation of hypoxia-inducible factor 1α. Biochemical and Biophysical Research Communications 460:4, pages 1041-1046.
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E . Anders Kolb, Valerie Sampson, Deborah Stabley, Alexa Walter, Katia Sol-Church, Timothy Cripe, Pooja Hingorani, Charlotte Hsieh Ahern, Brenda J. Weigel, James Zwiebel & Susan M. Blaney. (2015) A phase I trial and viral clearance study of reovirus (Reolysin) in children with relapsed or refractory extra-cranial solid tumors: A Children's Oncology Group Phase I Consortium report. Pediatric Blood & Cancer 62:5, pages 751-758.
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Yuki Katayama, Yuichi Terasawa, Masashi Tachibana, Hiroyuki Mizuguchi & Fuminori Sakurai. (2015) Proteolytic Disassembly of Viral Outer Capsid Proteins Is Crucial for Reovirus-Mediated Type-I Interferon Induction in Both Reovirus-Susceptible and Reovirus-Refractory Tumor Cells. BioMed Research International 2015, pages 1-12.
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V?ronique Sandekian & Guy Lemay. (2015) Amino acids substitutions in ?1 and ?1 outer capsid proteins of a Vero cell-adapted mammalian orthoreovirus are required for optimal virus binding and disassembly. Virus Research 196, pages 20-29.
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Shingo Hamano, Yoshinori Mori, Mineyoshi Aoyama, Hiromi Kataoka, Mamoru Tanaka, Masahide Ebi, Eiji Kubota, Tsutomu Mizoshita, Satoshi Tanida, Randal N. Johnston, Kiyofumi Asai & Takashi Joh. (2015) Oncolytic reovirus combined with trastuzumab enhances antitumor efficacy through TRAIL signaling in human HER2-positive gastric cancer cells. Cancer Letters 356:2, pages 846-854.
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Jun Gong & Monica M. Mita. (2014) Activated Ras Signaling Pathways and Reovirus Oncolysis: An Update on the Mechanism of Preferential Reovirus Replication in Cancer Cells. Frontiers in Oncology 4.
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Charles E. CarraherJr.Jr. & Michael R. Roner. (2014) Organotin polymers as anticancer and antiviral agents. Journal of Organometallic Chemistry 751, pages 67-82.
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Hung-Chuan Chiu, Sarah Richart, Fong-Yuan Lin, Wei-Li Hsu & Hung-Jen Liu. (2014) The Interplay of Reovirus with Autophagy. BioMed Research International 2014, pages 1-8.
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Romit Chakrabarty, Hue Tran, Iohann Boulay, Tanya Moran, Audrey Parenteau, Robert Tavcar, Maude Bigras, Allison Hagerman, Sarah Serl, Brad Thompson & Matt Coffey. (2013) Bio-distribution study of Reolysin® (pelareorep) through a single intravenous infusion in Sprague-Dawley rats. Investigational New Drugs 31:6, pages 1476-1486.
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Roland Jabre, V?ronique Sandekian & Guy Lemay. (2013) Amino acid substitutions in ?1 and ?1 outer capsid proteins are selected during mammalian reovirus adaptation to Vero cells. Virus Research 176:1-2, pages 188-198.
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J S Carew, C M Espitia, W Zhao, K R Kelly, M Coffey, J W Freeman & S T Nawrocki. (2013) Reolysin is a novel reovirus-based agent that induces endoplasmic reticular stress-mediated apoptosis in pancreatic cancer. Cell Death & Disease 4:7, pages e728-e728.
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Fabrice Le Bœuf, Cory Batenchuk, Markus Vähä-Koskela, Sophie Breton, Dominic Roy, Chantal Lemay, Julie Cox, Hesham Abdelbary, Theresa Falls, Girija Waghray, Harold Atkins, David Stojdl, Jean-Simon Diallo, Mads Kærn & John C. Bell. (2013) Model-based rational design of an oncolytic virus with improved therapeutic potential. Nature Communications 4:1.
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Don G. Morris, Xiaolan Feng, Lisa M. DiFrancesco, Kevin Fonseca, Peter A Forsyth, Alexander H. Paterson, Matt C. Coffey & Brad Thompson. (2012) REO-001: A phase I trial of percutaneous intralesional administration of reovirus type 3 dearing (Reolysin®) in patients with advanced solid tumors. Investigational New Drugs 31:3, pages 696-706.
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V?ronique Sandekian, Debbie Lim, Patrick Prud?homme & Guy Lemay. (2013) Transient high level mammalian reovirus replication in a bat epithelial cell line occurs without cytopathic effect. Virus Research 173:2, pages 327-335.
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Anne Bridgen. 2012. Reverse Genetics of RNA Viruses. Reverse Genetics of RNA Viruses 350 374 .
Diana J. M. van den Wollenberg, Iris J. C. Dautzenberg, Sanne K. van den Hengel, Steve J. Cramer, Raoul J. de Groot & Rob C. Hoeben. (2012) Isolation of Reovirus T3D Mutants Capable of Infecting Human Tumor Cells Independent of Junction Adhesion Molecule-A. PLoS ONE 7:10, pages e48064.
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Maya Shmulevitz, Shashi A. Gujar, Dae-Gyun Ahn, Adil Mohamed & Patrick W. K. Lee. (2012) Reovirus Variants with Mutations in Genome Segments S1 and L2 Exhibit Enhanced Virion Infectivity and Superior Oncolysis. Journal of Virology 86:13, pages 7403-7413.
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Robert A. AdairVictoria RoulstoneKaren J. ScottRuth MorganGerard J. NuovoMartin FullerDeborah BeirneEmma J. WestVictoria A. JenningsAilsa RoseJoan KyulaSheila FraserRajiv DaveDavid A. AnthoneyAlison MerrickRobin PrestwichAmer AldouriOliver DonnellyHardev PandhaMatt CoffeyPeter SelbyRichard VileGiles ToogoodKevin HarringtonAlan A. Melcher. (2012) Cell Carriage, Delivery, and Selective Replication of an Oncolytic Virus in Tumor in Patients. Science Translational Medicine 4:138.
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K R Kelly, C M Espitia, D Mahalingam, B O Oyajobi, M Coffey, F J Giles, J S Carew & S T Nawrocki. (2011) Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction, and augments bortezomib-mediated apoptosis in multiple myeloma. Oncogene 31:25, pages 3023-3038.
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Lisandra West, Smruti J. Vidwans, Nicholas P. Campbell, Jeff Shrager, George R. Simon, Raphael Bueno, Phillip A. Dennis, Gregory A. Otterson & Ravi Salgia. (2012) A Novel Classification of Lung Cancer into Molecular Subtypes. PLoS ONE 7:2, pages e31906.
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Virginie Brochu-Lafontaine & Guy Lemay. (2012) Addition of exogenous polypeptides on the mammalian reovirus outer capsid using reverse genetics. Journal of Virological Methods 179:2, pages 342-350.
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Shashi A Gujar, Da Pan, Paola Marcato, Katy A Garant & Patrick WK Lee. (2011) Oncolytic Virus-initiated Protective Immunity Against Prostate Cancer. Molecular Therapy 19:4, pages 797-804.
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Cristina Fillat, Anabel Jose, Xavier Bofill-De Ros, Ana Mato-Berciano, Maria Victoria Maliandi & Luciano Sobrevals. (2011) Pancreatic Cancer Gene Therapy: From Molecular Targets to Delivery Systems. Cancers 3:1, pages 368-395.
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Christopher L. Morton, Peter J. Houghton, E. Anders Kolb, Richard Gorlick, C. Patrick Reynolds, Min H. Kang, John M. Maris, Stephen T. Keir, Jianrong Wu & Malcolm A. Smith. (2010) Initial testing of the replication competent Seneca Valley virus (NTX‐010) by the pediatric preclinical testing program. Pediatric Blood & Cancer 55:2, pages 295-303.
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