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Oncolytic (replication-competent) adenoviruses as anticancer agents

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Pages 353-368 | Published online: 04 Feb 2010

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Andrew M. Gardeck, Jordan Sheehan & Walter C. Low. (2017) Immune and viral therapies for malignant primary brain tumors. Expert Opinion on Biological Therapy 17:4, pages 457-474.
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Lin Fang, Qian Cheng, Wenshun Liu, Jie Zhang, Yan Ge, Qi Zhang, Liantao Li, Junjie Liu & Junnian Zheng. (2016) Selective effects of a fiber chimeric conditionally replicative adenovirus armed with hep27 gene on renal cancer cell. Cancer Biology & Therapy 17:6, pages 664-673.
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Luigi Aurisicchio & Gennaro Ciliberto. (2012) Genetic cancer vaccines: current status and perspectives. Expert Opinion on Biological Therapy 12:8, pages 1043-1058.
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Mohsen Keshavarz, Seyed Mohammad Miri, Emad Behboudi, Yaser Arjeini, Hassan Dianat-Moghadam & Amir Ghaemi. (2022) Oncolytic virus delivery modulated immune responses toward cancer therapy: Challenges and perspectives. International Immunopharmacology 108, pages 108882.
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M. Kabong Nono, E.B. Megam Ngouonkadi, S. Bowong & H.B. Fotsin. (2022) Spatiotemporal dynamics and optimal control of glioma virotherapy enhanced by MEK Inhibitors. Results in Control and Optimization 7, pages 100101.
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Ahmad Firoz, Hani Ali, Suriya Rehman & Irfan Rather. (2022) Gastric Cancer and Viruses: A Fine Line between Friend or Foe. Vaccines 10:4, pages 600.
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Karoly Toth, Ann E. Tollefson, G. Chinnadurai, Clifford J. Bellone, Duane P. Grandgenett, Lynda A. Morrison & John E. Tavis. (2021) Biographical Feature: William S. M. Wold, Ph.D., 1944–2021. Journal of Virology 95:22.
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Fanny Georgi & Urs F. Greber. (2020) The Adenovirus Death Protein – a small membrane protein controls cell lysis and disease. FEBS Letters 594:12, pages 1861-1878.
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Devashree Jahagirdar, Sharwari Ghodke, Akshay Mergu, Aishwarya Nikam, Padma V. Devarajan, Ratnesh Jain & Prajakta Dandekar. 2019. Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis. Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis 197 228 .
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Yan Li, JinWoo Hong, Joung-Eun Oh, A-Rum Yoon & Chae-Ok Yun. (2018) Potent antitumor effect of tumor microenvironment-targeted oncolytic adenovirus against desmoplastic pancreatic cancer. International Journal of Cancer 142:2, pages 392-413.
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J. Patrick Condreay, Thomas A. Kost & Claudia A. Mickelson. 2017. Biological Safety. Biological Safety 221 246 .
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Pei-Hsin Cheng, Xiao-Mei Rao, Xiaoxian Duan, Xiao-Feng Li, Michael E. Egger, Kelly M. McMasters & H. Sam Zhou. (2014) Virotherapy targeting cyclin E overexpression in tumors with adenovirus-enhanced cancer-selective promoter. Journal of Molecular Medicine 93:2, pages 211-223.
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Weidong Xu, Zhenwei Zhang, Yuefeng Yang, Zebin Hu, Chi-Hsiung Wang, Melanie Morgan, Ying Wu, Ryan Hutten, Xianghui Xiao, Stuart Stock, Theresa Guise, Bellur S Prabhakar, Charles Brendler & Prem Seth. (2014) Ad5/48 Hexon Oncolytic Virus Expressing sTGFβRIIFc Produces Reduced Hepatic and Systemic Toxicities and Inhibits Prostate Cancer Bone Metastases. Molecular Therapy 22:8, pages 1504-1517.
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Y-F Yang, S-Y Xue, Z-Z Lu, F-J Xiao, Y Yin, Q-W Zhang, C-T Wu, H Wang & L-S Wang. (2014) Antitumor effects of oncolytic adenovirus armed with PSA-IZ-CD40L fusion gene against prostate cancer. Gene Therapy 21:8, pages 723-731.
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Rodinde HendrickxNicole StichlingJorien KoelenLukasz KurykAgnieszka LipiecUrs F. Greber. (2014) Innate Immunity to Adenovirus. Human Gene Therapy 25:4, pages 265-284.
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D Dhar, K Toth & W S M Wold. (2014) Cycles of transient high-dose cyclophosphamide administration and intratumoral oncolytic adenovirus vector injection for long-term tumor suppression in Syrian hamsters. Cancer Gene Therapy 21:4, pages 171-178.
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Hiroshi Nakashima & E. Antonio Chiocca. (2014) Switching a Replication-Defective Adenoviral Vector into a Replication-Competent, Oncolytic Adenovirus. Journal of Virology 88:1, pages 345-353.
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Tanner S. Miest & Roberto Cattaneo. (2013) New viruses for cancer therapy: meeting clinical needs. Nature Reviews Microbiology 12:1, pages 23-34.
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G K Grünwald, K Klutz, M J Willhauck, N Schwenk, R Senekowitsch-Schmidtke, M Schwaiger, C Zach, B Göke, P S Holm & C Spitzweg. (2012) Sodium iodide symporter (NIS)-mediated radiovirotherapy of hepatocellular cancer using a conditionally replicating adenovirus. Gene Therapy 20:6, pages 625-633.
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I-K Choi & C-O Yun. (2013) Recent developments in oncolytic adenovirus-based immunotherapeutic agents for use against metastatic cancers. Cancer Gene Therapy 20:2, pages 70-76.
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Youngjoo ChoiJun Chang. (2013) Viral vectors for vaccine applications. Clinical and Experimental Vaccine Research 2:2, pages 97.
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K Lee, S-T Yun, C-O Yun, B-Y Ahn & E-C Jo. (2011) S100A2 promoter-driven conditionally replicative adenovirus targets non-small-cell lung carcinoma. Gene Therapy 19:10, pages 967-977.
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Z Zhang, Z Hu, J Gupta, J D Krimmel, H M Gerseny, A F Berg, J S Robbins, H Du, B Prabhakar & P Seth. (2012) Intravenous administration of adenoviruses targeting transforming growth factor beta signaling inhibits established bone metastases in 4T1 mouse mammary tumor model in an immunocompetent syngeneic host. Cancer Gene Therapy 19:9, pages 630-636.
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Zebin HuJanhavi GuptaZhenwei ZhangHelen GersenyArthur BergYun Ju ChenZhiling ZhangHongyan DuCharles B. BrendlerXianghui XiaoKenneth J. PientaTheresa GuiseChung LeePaula H. SternStuart StockPrem Seth. (2012) Systemic Delivery of Oncolytic Adenoviruses Targeting Transforming Growth Factor-β Inhibits Established Bone Metastasis in a Prostate Cancer Mouse Model. Human Gene Therapy 23:8, pages 871-882.
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Juyi Seo, Chae-Ok Yun, Oh-Joon Kwon, Eun-Jin Choi, Jae-Young Song, Inho Choi & Kyung-Hyun Cho. (2012) A proteoliposome containing apolipoprotein A-I mutant (V156K) enhances rapid tumor regression activity of human origin oncolytic adenovirus in tumor-bearing zebrafish and mice. Molecules and Cells 34:2, pages 143-148.
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Stephen J Russell, Kah-Whye Peng & John C Bell. (2012) Oncolytic virotherapy. Nature Biotechnology 30:7, pages 658-670.
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Andrew Hofacre, Dominik Wodarz, Natalia L. Komarova & Hung Fan. (2012) Early infection and spread of a conditionally replicating adenovirus under conditions of plaque formation. Virology 423:1, pages 89-96.
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Yantao Wu, Xiaorong Zhang, Xiaobo Wang, Li Wang, Shunlin Hu, Xiufan Liu & Songshu Meng. (2012) Apoptin Enhances the Oncolytic Properties of Newcastle Disease Virus. Intervirology 55:4, pages 92-102.
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Kyle G. Potts, Mary M. Hitt & Ronald B. Moore. (2012) Oncolytic Viruses in the Treatment of Bladder Cancer. Advances in Urology 2012, pages 1-11.
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Guido Wollmann, Koray Ozduman & Anthony N. van den Pol. (2012) Oncolytic Virus Therapy for Glioblastoma Multiforme. The Cancer Journal 18:1, pages 69-81.
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William S.M. Wold & Karoly Toth. 2012. Applications of viruses for cancer therapy. Applications of viruses for cancer therapy 69 92 .
Liane Viru, Gregory Heller, Taavi Lehto, Kalle Pärn, Samir El Andaloussi, Ülo Langel & Andres Merits. (2011) Novel viral vectors utilizing intron splice-switching to activate genome rescue, expression and replication in targeted cells. Virology Journal 8:1.
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J Leja, D Yu, B Nilsson, L Gedda, A Zieba, T Hakkarainen, G Åkerström, K Öberg, V Giandomenico & M Essand. (2011) Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine tumor cells. Gene Therapy 18:11, pages 1052-1062.
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Luigi Aurisicchio & Gennaro Ciliberto. (2011) Emerging Cancer Vaccines: The Promise of Genetic Vectors. Cancers 3:3, pages 3687-3713.
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Wei Chen, Yuqiang Wu, Wei Liu, Guoying Wang, Xiaoyun Wang, Yang Yang, Wenjie Chen, Yan Tai, Minqiang Lu, Qijun Qian, Qi Zhang & Guihua Chen. (2011) Enhanced antitumor efficacy of a novel fiber chimeric oncolytic adenovirus expressing p53 on hepatocellular carcinoma. Cancer Letters 307:1, pages 93-103.
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Tobias Abel, Florian Kreppel, Manfred Ogris & Hildegard Büning. (2011) Wie Genvektoren mit dem richtigen Schlüssel ausgestattet werden. Die Zelloberfläche gezielt ansteuern. Pharmazie in unserer Zeit 40:3, pages 225-238.
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Taco G. Uil, Jort Vellinga, Jeroen de Vrij, Sanne K. van den Hengel, Martijn J. W. E. Rabelink, Steve J. Cramer, Julia J. M. Eekels, Yavuz Ariyurek, Michiel van Galen & Rob C. Hoeben. (2011) Directed adenovirus evolution using engineered mutator viral polymerases. Nucleic Acids Research 39:5, pages e30-e30.
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