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Miscellaneous

Immunotherapeutic and antitumour potential of thalidomide analogues

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Pages 675-682 | Published online: 23 Feb 2005

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Yuan Xiao Zhu, K. Martin Kortuem & A. Keith Stewart. (2013) Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma. Leukemia & Lymphoma 54:4, pages 683-687.
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Frederick A Luzzio & William D Figg. (2004) Thalidomide analogues: derivatives of an orphan drug with diverse biological activity. Expert Opinion on Therapeutic Patents 14:2, pages 215-229.
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Frank A Wollheim. (2002) TNF inhibition as therapy for rheumatoid arthritis. Expert Opinion on Investigational Drugs 11:7, pages 947-953.
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Articles from other publishers (40)

Bin Wang, Wanting Qiang, Jia Yi, Shouhong Gao, Bosu Meng, Yuhui Mu, Bolong Wang, Zhipeng Wang & Xia Tao. (2023) Simultaneous quantification of thalidomide, lenalidomide and pomadomide in plasma by LC-MS/MS. Journal of Pharmacological and Toxicological Methods 120, pages 107250.
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Santhamani Ramasamy & Selvakumar Subbian. 2023. Handbook of Animal Models in Neurological Disorders. Handbook of Animal Models in Neurological Disorders 343 352 .
Maliha Khan, Fredrick Hagemeister, Michael Wang & Sairah Ahmed. (2022) A review of pathobiology and therapies for classic Hodgkin lymphoma. Blood Reviews 55, pages 100949.
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Isaac Park, Tra Mi Phan & Jing Fang. (2021) Novel Molecular Mechanism of Lenalidomide in Myeloid Malignancies Independent of Deletion of Chromosome 5q. Cancers 13:20, pages 5084.
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Tiffany Li, David Mizrahi, David Goldstein, Matthew C. Kiernan & Susanna B. Park. (2021) Chemotherapy and peripheral neuropathy. Neurological Sciences 42:10, pages 4109-4121.
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Sara Ovejero & Jerome Moreaux. (2021) Multi-omics tumor profiling technologies to develop precision medicine in multiple myeloma. Exploration of Targeted Anti-tumor Therapy.
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Selvakumar Subbian & Gilla Kaplan. 2021. Advances in Host-Directed Therapies Against Tuberculosis. Advances in Host-Directed Therapies Against Tuberculosis 275 282 .
Alli Murugesan, Grégoire Lassalle-Claux, Lauren Hogan, Elise Vaillancourt, Ayyoub Selka, Katie Luiker, Min Ji Kim, Mohamed Touaibia & Tony Reiman. (2020) Antimyeloma Potential of Caffeic Acid Phenethyl Ester and Its Analogues through Sp1 Mediated Downregulation of IKZF1-IRF4-MYC Axis. Journal of Natural Products 83:12, pages 3526-3535.
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Ranjeet Kumar, Afsal Kolloli, Pooja Singh, Christopher Vinnard, Gilla Kaplan & Selvakumar Subbian. (2020) Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model. Frontiers in Cellular and Infection Microbiology 9.
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Jing Ma, Qian Li, Zhen Yu, Zeng Cao, Su Liu, Lin Chen, Han Li, Shuang Gao, Tinghui Yan, Yafei Wang & Qiang Liu. (2017) Immunotherapy Strategies Against Multiple Myeloma. Technology in Cancer Research & Treatment 16:6, pages 717-726.
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A.V. Petrov, D.V. Motorin, O.S. Pokrovskaya, E.S. Urnova, M.V. Nareiko, D.V. Babenetskaya, Yu.A. Alekseeva, L.L. Girshova, L.P. Mendeleeva & A.Yu. Zaritskii. (2017) Pomalidomide in Combination with Low-Dose Dexamethasone as the Treatment of "Double Refractory". Clinical oncohematology 10:3, pages 372-380.
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Howard Safran, Kevin P. Charpentier, Andreas Kaubisch, Kalyan Mantripragada, Gregory Dubel, Kimberly Perez, Katherine Faricy-Anderson, Thomas Miner, Yoko Eng, Joel Victor, Angela Plette, Joseph Espat, Pamela Bakalarski, Patti Wingate, David Berz, Denise Luppe, Diane Martel, Kayla Rosati & Santiago Aparo. (2015) Lenalidomide for Second-line Treatment of Advanced Hepatocellular Cancer. American Journal of Clinical Oncology 38:1, pages 1-4.
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Ahmed Omran, Muhammad Usman Ashhab, Na Gan, Huimin Kong, Jing Peng & Fei Yin. (2013) Effects of MRP8, LPS, and Lenalidomide on the Expressions of TNF- α , Brain-Enriched, and Inflammation-Related MicroRNAs in the Primary Astrocyte Culture . The Scientific World Journal 2013, pages 1-9.
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Selvakumar Subbian, Liana Tsenova, Paul O'Brien, Guibin Yang, Mi-Sun Koo, Blas Peixoto, Dorothy Fallows, Veronique Dartois, George Muller & Gilla Kaplan. (2011) Phosphodiesterase-4 Inhibition Alters Gene Expression and Improves Isoniazid ? Mediated Clearance of Mycobacterium tuberculosis in Rabbit Lungs. PLoS Pathogens 7:9, pages e1002262.
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Ming Jen Tsai, Chinpiao Chen, Sung-Ho Chen, Yen Ta Huang & Ted H. Chiu. (2011) Pomalidomide suppresses cerulein-induced acute pancreatitis in mice. Journal of Gastroenterology 46:6, pages 822-833.
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Irina Idler, Nupur Bhattacharya, Hartmut D?hner, Stephan Stilgenbauer & Daniel Mertens. (2011) Immune modulatory agents in hematopoietic malignancies. Cancer Treatment Reviews 37, pages S2-S7.
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Claudia Pessoa, Paulo Michel P. Ferreira, Letícia Veras C. Lotufo, Manoel O. de Moraes, Suellen M. T. Cavalcanti, Lucas Cunha D. Coêlho, Marcelo Z. Hernandes, Ana Cristina L. Leite, Carlos A. De Simone, Vlaudia M. A. Costa & Valdênia M. O. Souza. (2010) Discovery of Phthalimides as Immunomodulatory and Antitumor Drug Prototypes. ChemMedChem 5:4, pages 523-528.
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Boris Böll, Peter Borchmann, Max S. Topp, Mathias Hänel, Katrin S. Reiners, Andreas Engert & Ralph Naumann. (2010) Lenalidomide in patients with refractory or multiple relapsed Hodgkin lymphoma. British Journal of Haematology 148:3, pages 480-482.
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Scott G. Stewart, Carlos J. Braun, Marta E. Polomska, Mahdad Karimi, Lawrence J. Abraham & Keith A. Stubbs. (2010) Efforts toward elucidating Thalidomide’s molecular target: an expedient synthesis of the first Thalidomide biotin analogue. Organic & Biomolecular Chemistry 8:18, pages 4059.
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Alessandra Ferrajoli, Bang-Ning Lee, Ellen J. Schlette, Susan M. O'Brien, Hui Gao, Sijin Wen, William G. Wierda, Zeev Estrov, Stefan Faderl, Evan N. Cohen, Changping Li, James M. Reuben & Michael J. Keating. (2008) Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia. Blood 111:11, pages 5291-5297.
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Asher A. Chanan-Khan & Bruce D. Cheson. (2008) Lenalidomide for the Treatment of B-Cell Malignancies. Journal of Clinical Oncology 26:9, pages 1544-1552.
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Cindy H. Chau, William Dahut & William D. Figg. 2008. Angiogenesis. Angiogenesis 387 394 .
Naomi Galili, Jan Cerny & Azra Raza. (2007) Current Treatment Options: Impact of Cytogenetics on the Course of Myelodysplasia. Current Treatment Options in Oncology 8:2, pages 117-128.
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Dominique Verhelle, Laura G. Corral, Kevin Wong, Jessica H. Mueller, Laure Moutouh-de Parseval, Kristen Jensen-Pergakes, Peter H. Schafer, Roger Chen, Emilia Glezer, Gregory D. Ferguson, Antonia Lopez-Girona, George W. Muller, Helen A. Brady & Kyle W.H. Chan. (2007) Lenalidomide and CC-4047 Inhibit the Proliferation of Malignant B Cells while Expanding Normal CD34+ Progenitor Cells. Cancer Research 67:2, pages 746-755.
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Frederick A. Luzzio, Damien Y. Duveau & William D. Figg. (2006) A Chiral Pool Approach toward the Synthesis of Thalidomide Metabolites. HETEROCYCLES 70:1, pages 321.
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John Gerecitano & Owen A. O’Connor. 2006. Hodgkin’s and Non-Hodgkin’s Lymphoma. Hodgkin’s and Non-Hodgkin’s Lymphoma 413 460 .
V. Lima, G. A. C. Brito, F. Q. Cunha, C. G. Reboucas, B. A. A. Falcao, R. F. Augusto, M. L. P. Souza, B. T. Leitao & R. A. Ribeiro. (2005) Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters. European Journal of Oral Sciences 113:3, pages 210-217.
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S.A. Schey, P. Fields, J.B. Bartlett, I.A. Clarke, G. Ashan, R.D. Knight, M. Streetly & A.G. Dalgleish. (2004) Phase I Study of an Immunomodulatory Thalidomide Analog, CC-4047, in Relapsed or Refractory Multiple Myeloma. Journal of Clinical Oncology 22:16, pages 3269-3276.
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J. Blake Bartlett, Keith Dredge & Angus G. Dalgleish. (2004) The evolution of thalidomide and its IMiD derivatives as anticancer agents. Nature Reviews Cancer 4:4, pages 314-322.
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J B Bartlett, A Michael, I A Clarke, K Dredge, S Nicholson, H Kristeleit, A Polychronis, H Pandha, G W Muller, D I Stirling, J Zeldis & A G Dalgleish. (2004) Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers. British Journal of Cancer 90:5, pages 955-961.
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James M O'Donnell & Han-Ting Zhang. (2004) Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4). Trends in Pharmacological Sciences 25:3, pages 158-163.
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Maria R Nasca, Giuseppe Micali, Nina H Cheigh, Lee E West & Dennis P West. (2003) Dermatologic and Nondermatologic Uses of Thalidomide. Annals of Pharmacotherapy 37:9, pages 1307-1320.
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Peter H. Schafer, Anita K. Gandhi, Michelle A. Loveland, Roger S. Chen, Hon-Wah Man, Paul P. M. Schnetkamp, Gregor Wolbring, Sowmya Govinda, Laura G. Corral, Faribourz Payvandi, George W. Muller & David I. Stirling. (2003) Enhancement of Cytokine Production and AP-1 Transcriptional Activity in T Cells by Thalidomide-Related Immunomodulatory Drugs. Journal of Pharmacology and Experimental Therapeutics 305:3, pages 1222-1232.
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Seema Singhal & Jayesh Mehta. (2003) Novel Therapies in Multiple Myeloma. International Journal of Hematology 77:3, pages 226-231.
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Noopur Raje & Kenneth C. Anderson. (2002) Thalidomide and immunomodulatory drugs as cancer therapy. Current Opinion in Oncology 14:6, pages 635-640.
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K Dredge, J B Marriott, C D Macdonald, H-W Man, R Chen, G W Muller, D Stirling & A G Dalgleish. (2002) Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects. British Journal of Cancer 87:10, pages 1166-1172.
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Andrea Thiele, Renate Bang, Michael G?tschow, Manuela Rossol, Sebastian Loos, Kurt Eger, Gisa Tiegs & Sunna Hauschildt. (2002) Cytokine modulation and suppression of liver injury by a novel analogue of thalidomide. European Journal of Pharmacology 453:2-3, pages 325-334.
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Tracy E. Kim & John R. Murren. (2012) Angiogenesis in Non-Small Cell Lung Cancer. American Journal of Respiratory Medicine 1:5, pages 325-338.
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J B MARRIOTT, I A CLARKE, K DREDGE, G MULLER, D STIRLING & A G DALGLEISH. (2002) Thalidomide and its analogues have distinct and opposing effects on TNF- α and TNFR2 during co-stimulation of both CD4+ and CD8+ T cells . Clinical and Experimental Immunology 130:1, pages 75-84.
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Keith Dredge, J. Blake Marriott, Stephen M. Todryk, George W. Muller, Roger Chen, David I. Stirling & Angus G. Dalgleish. (2002) Protective Antitumor Immunity Induced by a Costimulatory Thalidomide Analog in Conjunction with Whole Tumor Cell Vaccination Is Mediated by Increased Th1-Type Immunity. The Journal of Immunology 168:10, pages 4914-4919.
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