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Cytochrome P450-based cancer gene therapy: current status

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Pages 857-868 | Published online: 23 Feb 2005

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Bérénice Giraud, Guillaume Hebert, Alain Deroussent, Gareth J Veal, Gilles Vassal & Angelo Paci. (2010) Oxazaphosphorines: new therapeutic strategies for an old class of drugs. Expert Opinion on Drug Metabolism & Toxicology 6:8, pages 919-938.
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Pamela J Russell & Aparajita Khatri. (2006) Novel gene-directed enzyme prodrug therapies against prostate cancer. Expert Opinion on Investigational Drugs 15:8, pages 947-961.
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Jing Zhang, Quan Tian, Sui Yung Chan, Shu Chuen Li, Shufeng Zhou, Wei Duan & Yi-Zhun Zhu. (2005) Metabolism and Transport of Oxazaphosphorines and the Clinical Implications. Drug Metabolism Reviews 37:4, pages 611-703.
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Articles from other publishers (22)

Rishabh Kaushik, Sheeza Khan, Meesha Sharma, Srinivasan Hemalatha, Zeba Mueed & Nitesh K. Poddar. (2020) Role of Cytochrome P450 in Prostate Cancer and its Therapy. Current Enzyme Inhibition 16:1, pages 63-73.
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James C Neil. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences 1 10 .
Zahra Karjoo, Vidya Ganapathy & Arash Hatefi. 2014. Gene Therapy of Cancer. Gene Therapy of Cancer 77 91 .
M.G. Bourke, S. Salwa, K.J. Harrington, M.J. Kucharczyk, P.F. Forde, M. de Kruijf, D. Soden, M. Tangney, J.K. Collins & G.C. O’Sullivan. (2011) The emerging role of viruses in the treatment of solid tumours. Cancer Treatment Reviews 37:8, pages 618-632.
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G. Gonzalez-Aseguinolaza, J. Prieto & R. Hernandez-Alcoceba. (2011) Gene therapy of liver cancer: an updateThérapie génique du cancer du foie : le point. Journal Africain du Cancer / African Journal of Cancer 3:3, pages 180-192.
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Rubi Mahato, Wanyi Tai & Kun Cheng. (2011) Prodrugs for improving tumor targetability and efficiency. Advanced Drug Delivery Reviews 63:8, pages 659-670.
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Peter Hlavica. (2009) Assembly of non-natural electron transfer conduits in the cytochrome P450 system: A critical assessment and update of artificial redox constructs amenable to exploitation in biotechnological areas. Biotechnology Advances 27:2, pages 103-121.
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Monica Stewart, Nancy Mackay, Linda Hanlon, Karen Blyth, Linda Scobie, Ewan Cameron & James C. Neil. (2007) Insertional Mutagenesis Reveals Progression Genes and Checkpoints in MYC/Runx2 Lymphomas . Cancer Research 67:11, pages 5126-5133.
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Daniel Portsmouth, Juraj Hlavaty & Matthias Renner. (2007) Suicide genes for cancer therapy. Molecular Aspects of Medicine 28:1, pages 4-41.
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Rubén Hernández-Alcoceba, Bruno Sangro & Jesús Prieto. (2007) Gene therapy of liver cancer. Annals of Hepatology 6:1, pages 5-14.
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Youssef Jounaidi, Chong-Sheng Chen, Gareth J. Veal & David J. Waxman. (2006) Enhanced antitumor activity of P450 prodrug-based gene therapy using the low K m cyclophosphamide 4-hydroxylase P450 2B11 . Molecular Cancer Therapeutics 5:3, pages 541-555.
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Partha Roy & David J. Waxman. (2006) Activation of oxazaphosphorines by cytochrome P450: Application to gene-directed enzyme prodrug therapy for cancer. Toxicology in Vitro 20:2, pages 176-186.
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Ruben Hernandez-Alcoceba. (2006) Gene therapy of liver cancer. World Journal of Gastroenterology 12:38, pages 6085.
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Lawrence S Young, Peter F Searle, David Onion & Vivien Mautner. (2006) Viral gene therapy strategies: from basic science to clinical application. The Journal of Pathology 208:2, pages 299-318.
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Meera Kumarakulasingham, Patrick H. Rooney, Sinclair R. Dundas, Colin Telfer, William T. Melvin, Stephanie Curran & Graeme I. Murray. (2005) Cytochrome P450 Profile of Colorectal Cancer: Identification of Markers of Prognosis. Clinical Cancer Research 11:10, pages 3758-3765.
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Marina Tychopoulos, Laurent Corcos, Philippe Genne, Philippe Beaune & Isabelle de Waziers. (2005) A virus-directed enzyme prodrug therapy (VDEPT) strategy for lung cancer using a CYP2B6/NADPH-cytochrome P450 reductase fusion protein. Cancer Gene Therapy 12:5, pages 497-508.
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Christopher M. Halloran, Paula Ghaneh, Eithne Costello & John P. Neoptolemos. (2005) Trials of gene therapy for pancreatic carcinoma. Current Gastroenterology Reports 7:3, pages 165-169.
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Jeremy P. Braybrooke, Andrew Slade, Gael Deplanque, Richard Harrop, Srinivasan Madhusudan, Martin D. Forster, Rachel Gibson, Andreas Makris, Denis C. Talbot, Jan Steiner, Linda White, On Kan, Stuart Naylor, Miles W. Carroll, Sue M. Kingsman & Adrian L. Harris. (2005) Phase I Study of MetXia-P450 Gene Therapy and Oral Cyclophosphamide for Patients with Advanced Breast Cancer or Melanoma. Clinical Cancer Research 11:4, pages 1512-1520.
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Bertrand Rochat. (2005) Role of Cytochrome P450 Activity in the Fate of Anticancer Agents and in Drug Resistance. Clinical Pharmacokinetics 44:4, pages 349-366.
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M. B. Nthangeni, P. Urban, D. Pompon, M. S. Smit & J.‐M. Nicaud. (2004) The use of Yarrowia lipolytica for the expression of human cytochrome P450 CYP1A1 . Yeast 21:7, pages 583-592.
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Morag C. E. McFadyen, William T. Melvin & Graeme I. Murray. (2004) Cytochrome P 450 enzymes: Novel options for cancer therapeutics . Molecular Cancer Therapeutics 3:3, pages 363-371.
Crossref
Hans E. J. Hofland, Frank L. Sorgi & Edward G. Spack. 2004. Cellular Drug Delivery. Cellular Drug Delivery 67 80 .

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